TL PGF2a
- Thread starter Nullifidian
- Start date
fedaykin
Board Supporter
Dinoprost-Gel Transdermal Fat Reduction PGF-2a
you rub a little bit in the palm of your hand then spread on the area you want to lose weight, you can use this twice a day, the dmso is the carrier and it takes the pgf-2a into the fat, the pgf-2a turns the mature fat cells into imature fat cells, the imature fat cells cannot store fat so the fat is released into the blood steam and by excercisng you burn off that fat, after applying you may get a bit of an itch, if you do use some aloe vera cream to cure the itch, if you get a slight tigthness in your chest and maybe a small cough that lasts just for a moment it is a good sign you have applied enough,
Please note this product is not safe for women to take.
QFS Dinoprost-Gel, Transdermal Fat Reduction active ingredients Dinoprost Tromethamine 150mg ( Prostraglandin F2 alpha) and Dimethylsulfoxide (DMSO 25%)
Prostaglandin F2alpha is a potent inhibitor of adipocyte precursor differentiation and a physiological negative modulator of adipocyte function (ie triglyceride accumulation) through stimulation of transforming growth factor-alpha mRNA expression. It initiates a cascade of effects in the adipoctes which have physiological importance to reducing the size and it appears number of mature cells,long after PGf-2a is cleared from the system
Mature adipose cells only shrink in size in response to restricted caloric intake or increased metabolic demand. Before now the only method of reducing the number of fat cells was liposuction. It now appears that Pgf-2a applied topically can have the same same effecst as diet and liposuction. Pgf-2a can reduce the size of mature adipocytes and the number of mature adipocytes through negative modulation and reversing the process of differentiation
There are no studies on topical application. DMSO does carry PGF-2a through the dermal layers and the low concentration spread over a large area is ideal for the intended purpose. One cannot spread PGf-2a (or anyother substance) over the surface area that one can with DMSO topical application. The idea being that you need to interact as many molecules of PGF-2a with as many mature fat cells as possible. The biggest asset to DMSO as a carrier is the ability to spread the PGF-2a applicatiion over a large surface area, thereby maximising the interactuion of the number PGF-2a molucules with the maximum number of fat cells. This is where the DMOS method really shines. QFS is not masking the smell of the DMSO. It is not that bad and goes away in about 5 minutes.
It is important to remember that dinoprost tromethamine does not burn the released fatty acids, aerobic exercise and or T3 will take care of that. PGF-2a only changes the way fats are stored and the formation and function of adipose tissue. As well I find that about half of the time I feel a tickle in the back of my throat and sometimes I have a full out coughing fit. This says to me that I have applied a good dosage.
Here are some studies that support PGF-2a and negative modulation of adipose tissue.
Endocrinology 1995 Aug;136(8):3222-9
Prostaglandin F2 alpha stimulates transforming growth factor-alpha expression in adipocyte precursors.
Lepak NM, Serrero G.
W. Alton Jones Cell Science Center, Inc., Lake Placid, New York 12946, USA.
Transforming growth factor-alpha (TGF alpha) and prostaglandin F2 alpha (PGF2 alpha) are potent inhibitors of adipocyte differentiation. We demonstrate here that TGF alpha messenger RNA (mRNA) is expressed in freshly isolated fat pads and in primary culture of adipocyte precursors cultivated in defined medium before and after differentiation. We show that PGF2 alpha stimulated TGF alpha mRNA expression in a dose-dependent manner. PGF2 alpha also stimulated TGF alpha production in the culture medium of adipocyte precursors in primary culture. PGF2 alpha stimulated TGF alpha mRNA expression in both undifferentiated and differentiated cells. 9 alpha,11 beta-PGF2 alpha, which also inhibited adipose differentiation, stimulated TGF alpha mRNA expression similarly to PGF2 alpha, whereas other PGs had no effect on TGF alpha mRNA expression. The time-course experiment indicates that the stimulation of TGF alpha mRNA expression by PGF2 alpha is observed within 6 h of exposure to PGF2 alpha and is inhibited by treatment of the cells with actinomycin D. The effect of PGF2 alpha on TGF alpha expression did not require activation of protein kinase C and was fully reversible. As both TGF alpha and PGF2 alpha are inhibitors of adipose differentiation, it is suggested that stimulation of TGF alpha expression by PGF2 alpha could represent an amplification mechanism to modulate adipocyte precursor differentiation and adipocyte function within the adipose tissue.
Int J Obes Relat Metab Disord 1996 Mar;20 Suppl 3:S58-64 R
Endocrine and paracrine negative regulators of adipose differentiation.
Serrero G, Lepak N.
W Alton Jones Cell Science Center, Inc, Lake Placid, NY 12946, USA.
Obesity which is characterized by an abnormal adipose tissue development is a first degree public health hazard in industrialized countries. One important aspect in the study of adipose tissue development is to investigate the hormonal control of proliferation and differentiation. Any qualitative or quantitative change in these hormones or their receptors can result in abnormalities in the process of proliferation and/or differentiation possibly leading to obesity. Therefore, it is important to identify these factors and investigate their mechanism of action. We have concentrated our efforts in the study of factors triggering differentiation (positive regulators) and also of factors inhibiting differentiation (negative regulators). The present paper provides evidence of the importance of EGF/TGF-alpha and of PGF2 alpha as differentiation inhibitors for adipocyte precursors in primary culture. Data presented here also demonstrate that TGF-alpha is expressed in adipose tissue and that its expression is specifically stimulated by PGF2 alpha, thus suggesting the existence of an amplification mechanism between two differentiation inhibitors within the adipose tissue. The importance of these two types of differentiation inhibitors in the regulation of adipose tissue development is discussed.
__________________
^^^ the above was copied from osbb^^
What ya guys think???:blink:
you rub a little bit in the palm of your hand then spread on the area you want to lose weight, you can use this twice a day, the dmso is the carrier and it takes the pgf-2a into the fat, the pgf-2a turns the mature fat cells into imature fat cells, the imature fat cells cannot store fat so the fat is released into the blood steam and by excercisng you burn off that fat, after applying you may get a bit of an itch, if you do use some aloe vera cream to cure the itch, if you get a slight tigthness in your chest and maybe a small cough that lasts just for a moment it is a good sign you have applied enough,
Please note this product is not safe for women to take.
QFS Dinoprost-Gel, Transdermal Fat Reduction active ingredients Dinoprost Tromethamine 150mg ( Prostraglandin F2 alpha) and Dimethylsulfoxide (DMSO 25%)
Prostaglandin F2alpha is a potent inhibitor of adipocyte precursor differentiation and a physiological negative modulator of adipocyte function (ie triglyceride accumulation) through stimulation of transforming growth factor-alpha mRNA expression. It initiates a cascade of effects in the adipoctes which have physiological importance to reducing the size and it appears number of mature cells,long after PGf-2a is cleared from the system
Mature adipose cells only shrink in size in response to restricted caloric intake or increased metabolic demand. Before now the only method of reducing the number of fat cells was liposuction. It now appears that Pgf-2a applied topically can have the same same effecst as diet and liposuction. Pgf-2a can reduce the size of mature adipocytes and the number of mature adipocytes through negative modulation and reversing the process of differentiation
There are no studies on topical application. DMSO does carry PGF-2a through the dermal layers and the low concentration spread over a large area is ideal for the intended purpose. One cannot spread PGf-2a (or anyother substance) over the surface area that one can with DMSO topical application. The idea being that you need to interact as many molecules of PGF-2a with as many mature fat cells as possible. The biggest asset to DMSO as a carrier is the ability to spread the PGF-2a applicatiion over a large surface area, thereby maximising the interactuion of the number PGF-2a molucules with the maximum number of fat cells. This is where the DMOS method really shines. QFS is not masking the smell of the DMSO. It is not that bad and goes away in about 5 minutes.
It is important to remember that dinoprost tromethamine does not burn the released fatty acids, aerobic exercise and or T3 will take care of that. PGF-2a only changes the way fats are stored and the formation and function of adipose tissue. As well I find that about half of the time I feel a tickle in the back of my throat and sometimes I have a full out coughing fit. This says to me that I have applied a good dosage.
Here are some studies that support PGF-2a and negative modulation of adipose tissue.
Endocrinology 1995 Aug;136(8):3222-9
Prostaglandin F2 alpha stimulates transforming growth factor-alpha expression in adipocyte precursors.
Lepak NM, Serrero G.
W. Alton Jones Cell Science Center, Inc., Lake Placid, New York 12946, USA.
Transforming growth factor-alpha (TGF alpha) and prostaglandin F2 alpha (PGF2 alpha) are potent inhibitors of adipocyte differentiation. We demonstrate here that TGF alpha messenger RNA (mRNA) is expressed in freshly isolated fat pads and in primary culture of adipocyte precursors cultivated in defined medium before and after differentiation. We show that PGF2 alpha stimulated TGF alpha mRNA expression in a dose-dependent manner. PGF2 alpha also stimulated TGF alpha production in the culture medium of adipocyte precursors in primary culture. PGF2 alpha stimulated TGF alpha mRNA expression in both undifferentiated and differentiated cells. 9 alpha,11 beta-PGF2 alpha, which also inhibited adipose differentiation, stimulated TGF alpha mRNA expression similarly to PGF2 alpha, whereas other PGs had no effect on TGF alpha mRNA expression. The time-course experiment indicates that the stimulation of TGF alpha mRNA expression by PGF2 alpha is observed within 6 h of exposure to PGF2 alpha and is inhibited by treatment of the cells with actinomycin D. The effect of PGF2 alpha on TGF alpha expression did not require activation of protein kinase C and was fully reversible. As both TGF alpha and PGF2 alpha are inhibitors of adipose differentiation, it is suggested that stimulation of TGF alpha expression by PGF2 alpha could represent an amplification mechanism to modulate adipocyte precursor differentiation and adipocyte function within the adipose tissue.
Int J Obes Relat Metab Disord 1996 Mar;20 Suppl 3:S58-64 R
Endocrine and paracrine negative regulators of adipose differentiation.
Serrero G, Lepak N.
W Alton Jones Cell Science Center, Inc, Lake Placid, NY 12946, USA.
Obesity which is characterized by an abnormal adipose tissue development is a first degree public health hazard in industrialized countries. One important aspect in the study of adipose tissue development is to investigate the hormonal control of proliferation and differentiation. Any qualitative or quantitative change in these hormones or their receptors can result in abnormalities in the process of proliferation and/or differentiation possibly leading to obesity. Therefore, it is important to identify these factors and investigate their mechanism of action. We have concentrated our efforts in the study of factors triggering differentiation (positive regulators) and also of factors inhibiting differentiation (negative regulators). The present paper provides evidence of the importance of EGF/TGF-alpha and of PGF2 alpha as differentiation inhibitors for adipocyte precursors in primary culture. Data presented here also demonstrate that TGF-alpha is expressed in adipose tissue and that its expression is specifically stimulated by PGF2 alpha, thus suggesting the existence of an amplification mechanism between two differentiation inhibitors within the adipose tissue. The importance of these two types of differentiation inhibitors in the regulation of adipose tissue development is discussed.
__________________
^^^ the above was copied from osbb^^
What ya guys think???:blink:
fedaykin
Board Supporter
one more quote, from big cat on PGF2a transdermal:
For localized fat loss ?
Dissolve the PGF2 by adding benzyl alcohol until completely dissolved, then add a 50/50 mixture of acetone and isopropanol until you get a total volume that gives you the mg/ml ratio you want.
Then apply as many ml as you deem necessary to the target area.
For localized fat loss ?
Dissolve the PGF2 by adding benzyl alcohol until completely dissolved, then add a 50/50 mixture of acetone and isopropanol until you get a total volume that gives you the mg/ml ratio you want.
Then apply as many ml as you deem necessary to the target area.
Poobah
Board Supporter
sorry guys.. I don't around her as much as I used too...
but no further updates.. I haven't used it since I put 2.5mg in each bicep. But like I said previously feeling nautious just doesn't mix well with continual 2 hour feedings. Just not my cup of tea.
I was just reading through to see if I can find out anything else.
Who's all has pinned it so far? Is anyone else finding it painless as far as injections go?
Anyone have any results with transdermal application to the gut, and did it make your spinxter blow?
:run:
but no further updates.. I haven't used it since I put 2.5mg in each bicep. But like I said previously feeling nautious just doesn't mix well with continual 2 hour feedings. Just not my cup of tea.
I was just reading through to see if I can find out anything else.
Who's all has pinned it so far? Is anyone else finding it painless as far as injections go?
Anyone have any results with transdermal application to the gut, and did it make your spinxter blow?
:run:
TooPowerful4u
New member
iv read about this **** over n over and never once have i read about the results someone got on this stuff. is it pure bull****?
Schwaugher
Member
Here are a few copy and pasted for it's anabolic effects from basskiller, the line and word spacing for screwed up in a few places making a little harder to read.
Invalid Link Removed
"PGF2A Report
by Ranger
The Personals!!!
This section contains a lot of personal experiences, and side effects
with this new drug…
Big Brother Val!
According to Val pumps are INSANE! In addition, Val, as the rest of us found; needed the unrestricted use of the bathroom…Does it hurt? In Val's words, " This **** is awesome…Hurts like ****ing hell!" As Val
stayed with the injections, and SLOWLY increased the dosage, we got a report from him at the 2-week point of the cycle. Injections and dosages varied, but I will relate this as Val told it, " Hitting the arms 12 times a
day….3 in each Biceps, 3 in each Triceps, for a total of 6cc's a day. I am being burned out on injecting myself so often, especially in the Biceps. The pain is reducing now, and I do not feel sick. Still get shortness of breath, and tightness in the chest each time. There is a visible difference in growth thus far, and my body fat has dropped significally." As you can see, and as most of us found, the injections become a major burden to deal with, the benefit though, is the visible growth all of us have saw…it is a very hard choice. This was taken off the E! litefitness Board as one of Big Brother Val's Post's! I was injecting my arms 4 times a week. It went like this: Sun:..shoot/arms...... lift/rest Mon:..shoot/shoulders..lift/arms, pump/chest Tues:.shoot/shoulders..lift/back, pump/shouders Wed:..shoot/shoulders..lift/legs Thurs.shoot/arms.......lift/chest, pump/arms Fri:..shoot/arms.......lift/shoulders, pump/calves Sat:..shoot/arms.......lift/rest Then repeat. I've switched
it up a bit, and have found a lot better response... in a matter of a few days, I have new stretch marks starting on my tri's... and my arms have never felt so full. Now my lifting schedule is the same. However, I switched up the dosage on PGF2A. I read in the articles by Dharkam that you should shoot 24 hours before training a muscle... then wait 2 days after that to shoot it again. Maybe even three days if you train hard enough. I personally have found that if I shoot the muscle group the same day I train it... that my lifts go better... my pumps are abso!
lutely incredible... and I keep my pump a lot longer, as well as feel more pumped the next couple of days. Now I follow this schedule:
Sun:..shoot/arms...... lift/rest
Mon:..shoot/ARMS.......lift/arms, pump/chest
Tues:.shoot/shoulders..lift/back, pump/shouders
Wed:..shoot/shoulders..lift/legs Thurs.shoot/arms.......lift/chest, pump/arms
Fri:..shoot/SHOULDERS.......lift/shoulders, pump/calves
Sat:..shoot/arms.......lift/rest Then repeat.
Val wrote "It's only a switch of two days... but for my personal results it's really working great. On arm day, I take six cc's throughout the day. I will up the dosage coming up next week, and see how that goes. My side effects are gone... besides the odd feeling in the chest... and the intense muscle pain. Just thought I would give an update for those interested in this." I have just come off a Sustanon, Eq. cycle... and will be doing a cycle of test, Eq, and Dbol after my PGF2A run. The pain sucks, absolutely. However, I want to focus on my arms and deltas, so they can catch up. A lot harder to do on regular gear. "My poundage's are definitely affected. Not nearly as dramatic as stated in that article, though. I was curling 65 lb. dumbbells for eight reps before I started this. Now I'm curling 45 lb. dumbbells and hoping for eight. The pump is insane." "One of the great things, is that you can REALLY feel the muscle working. Really, helps to focus on that muscle group and feel it work throughout the entire range of motion. The pain factor is intense... and the muscle REALLY burns bad while training it. More so when you shoot on the same day you train it. That feeling isn't as intense if you stop shooting that muscle 24 hours before you train it." "I'm never sore after a workout the following day, but hot damn am I sore after each shot." "Well.... the muscle pain you experience is INTENSE!! Right now for example... I hit arms on my lunch break... (got the most incredible pump I have EVER had, by the way), came back, and shot in the bathroom. My arms hurt so badly right now, I can't explain it. Can't bend 'em very well, or straighten them all the way.... I have a tight feeling in the chest... Nevertheless, GODDAMN!!! This is
the biggest my arms have EVER looked!! IT'S ****IN' INSANE!! I literally cannot put on the shirt I was wearing before break... it won't stretch enough to fit on my arms!!"
Jeff rys!
After 4 to 5 weeks of PGF2A injections, Jeff reported the following to me. " I'm doing 8 shots a day at .5cc. Left Biceps, Right Biceps would equal one full cc. I am fed up with the numerous injections, and if I
can overcome being fed up with the needle, I will inject more. As for the results, ½ on arms when flexed. I did shoulders as well, and they are thicker. I did some injecting in the abs, by pulling the skin up, and
injecting. The site turned red, in a spot of around 3 square inches. I am now injecting into the muscle of the abs, but this is dangerous because you may pass through and hit an organ. I only inject abs once a week, and the site gets thick, as if a vein is iriated. It is not a vein, but it feels like it. I have dropped 11 pounds, and everyone says how good I look…. I tried lower back, and chest as well, not much results, but I think it works best if you inject in the same spot a lot more. I feel it's a good alternative to steroids…But, I don't know how safe it is."
Efigy!
Okay, here's my info: 1/2 cc in both body parts (1cc total)at a time. biceps morning, triceps noon, delt's night. this is my third day. about 5 min. after injection stinging in bodypart. about 10 min. after injection coughing and "weird feeling" in my lungs, numb lips, intense waves of pain in the body part injected. about 20-30 min. after injection slight to moderate urge to ****, not that bad though, no running to bathroom. One and ½ to two hours after injection all bad sides are gone. pleasant pump/pain in bodypart. I am noticing a big difference already! Oh
yea! I almost forgot, major chills and feeling VERY cold about 10 min. after and lasts about 30 min.
BIGDAWG!
What's up guys.. as we speak, I'm on my first dose of PGF2A. It was a little ****ed up how it happened so I will just explain from the beginning. I decided to try the DMSO method first. I guess I am just curious like that. I put 1/4 of a cc on each gauze pad and some DMSO gel. I had my wife tape the **** to my shoulders and I waited. It got warm, and I was light- headed as well. I felt weird once it was absorbing and the DMSO gets warm! I'm not sure if its that or the PGF2A, but whatever. I did 1/4 of a cc because I just wanted to test it out a little. Well, after having it on there for like 30 minutes, I said **** it, loaded another one up with 1/4 cc, and put them on my bicep's. Therefore, as I am typing this I have the pads on both areas and I am heating up rather warm. From what my boy tells me, the gel takes a little while to absorb, so I am giving it some time. I will say, my biceps's feel much-pumped right now. Kinda cool. He also told me, what he noticed was with the DMSO, its like a more "all around" growth, where as with the pin, its like a peak growth. Not all around means the whole body. It means the whole muscle you put it on. He explained to me how the vessel's work, this dudes like a medical student, so I trust him. **** I gotta ****. Hang on! Ok I am back. Goddamn did not even see that one coming! Ok I just took off the deltoid pads; it has been almost an hour now. Well it looks like a big ass rash on my deltoids now. In addition, its WARM. The biceps's are still kicking full force now. I think the dose is the thing that determines the whole **** your pants thing and all just hope I get some results. My biceps are pumped! In addition, my veins are coming out like crazy from my BI's on down. Well, I am gonna go for now. Next time I will try the inject. ****, I can't wait for that ****! Okay, after reading over the Ranger's e-mail to me a couple of times I said **** it and got up the balls to do it. I don't know why, but I was like, REALLY thinking it was going to be BAD. So after some prepping and all I had my wife stick my delts. when she injected, I didn't feel ****..nothing. in fact, I almost thought my **** was bunk..lol then I got light headed..like a paint high. then I felt a little soreness in the sites. I was waiting for the other sides and I got a couple cramps in the stomach and that was about it. now please keep in mind, I get explosive ****s all the time.. I think my body was laughing at the PGF2A, McDonalds is worse. hehe As time went on ,I began to get more sore.. like I had did a BIG set of laterals I guess. Once the soreness starts, the short breath came. not too bad though.. I only felt it when I TRIED to breathe in hard. after that all sets in, nothing else happened.. I coughed a few times but that's it. If this is what's its like ,then I shouldn't have a problem with this. Not for the results, it's supposed to give. Ranger's right on this one.. after everything I read, I was waiting for! it to be PURE HELL, but this is not the case. I will now retract my statement about the taking a **** part. I had a FULL stomach on my last inject, in fact I had just eaten a mcflurry well, at first I got a little rumble down there so I grabbed my favorite car audio magazine and went to town. the rumble was followed by some NASTY unloading, lets just say I made a swamp. **** it though, I felt lean as a mofo once it was over! the burning/pain part isn't ****, on the delts at least, I'm sure the BI's would be worse but I'm not worried about it. I guess I was
thinking it would be like REAL bad,but its not. as for injecting, I've sort of came up with my own little schedule. I figure this week I want to hit triceps and shoulders. so one-day ill do my tri's twice and shoulders once, then the next day ill change that around. this way they are getting hit twice one day and once the next day. I can't think of another way to do it without injecting like way more. The injects aren't bad! at all, I could stand it like 5 times a day, but I don't have the time to take that many 45 min ****s. Ranger, man my ****ing lips get numb now! LOL the good thing is, I'm getting used to the sides now, and they don't bother me. it did bother me last night when my wife hit a nerve in my tricep. here is a list of my experience so far..
1. the inject, no pain unless she hits the nerve.. ouch
2. slight sting on injection spot
3. begin to feel warm.. a little dizzy
4. get small cramps in stomach
5. sites get a little more sore
6. lips numb
7. HUGE ****, liquid
8. everything goes away.. chills sometimes. that's it.. it all lasts about 20-30 minutes for me and I'm done. I do this **** on my lunch break now. once one side hits, another goes away. PGF2A is not painful, it's ****ing annoying. it sucks to have to feel that way three times a day, that's why it sucks.
Ranger
Well, I guess you could say I was a little more experimental in my use with PGF2A. I wanted to see how far I could take it, and what happened, and what I could do to minimize the side effects without hindering the growth process……Well, I don't have all the answers to this one. I do know it takes dedication, as Val has showed us, and you will have to endure some pretty nasty sides from time to time….bottom line!!! The choice is yours, and yours alone!! I started out at 2.5mg's per bicep twice a day from the start. I experienced all of the aforementioned sides….Breathing, numb lips, diarrhea, hypoglycemia, muscle pain….the list goes on. However, in 2 weeks my arms grew ½ inches…doesn't sound like much? It's permanent 85growth…that's good! I did get pretty ****y at the end of the 2nd week and decided to inject calves…I injected 1cc per muscle, per leg, for a total of 4cc's or 20mg's. My GOD was the pain intense!! I couldn't walk for 30 minutes, Breathing was labored, lips complet! ely numb, mucous in my throat, and when the diarrhea came, I had to crawl to the bathroom. I was laughing and wanting to cry at the same time, but I made it(barely)! I will say this now…UP THE DOSAGE SLOWLY!!! How much? I cannot give you the answers to that, everyone will be different. BIGDAWG'S side effects are no where near that of Val', Jeff, and mine. However, take it slowly! I decided to try a very strict diet to see the effects…I only had 100 grams of Carbohydrates per day, all before lunch…low fat. The third day into this diet I was getting added side effects….light headed, headaches, cold chills, shaky. I checked my blood sugar levels the fourth day after my morning injection….49mg/dl. Yup, Hypoglycemia(low blood sugar). I quickly drank some orange juice, protein shake, and ate some Gram Crackers…the sides quickly subsided. I even made a Doctor's Appt. to have this checked further…everything came out fine…nothing! Here's what I found to work best for me…around 1 hour b! before injection, have a bowl of oatmeal, and a small protein shake. After your injection, and the sides(diarrhea) have subsided, eat 3 tablets of Glucose(chewable orange flavored…yummy!), and have a large protein shake. You can buy these over the counter and is a great sugar free Carb Booster!! This worked great for me!! I found out, and all who are using
this will agree…I have become leaner than I ever have!! As my body fat dropped, my arms and calves continued to grow, as did the rest of my body. Only at a slower pace. INJECTIONS SUCK!! You wanna grow?? Get used to the idea!! I use 28 or 29-gauge 1 inch Insulin pins. Works great Bro's! After three weeks, and all will once again agree, you will get needle phobia…heh heh heh…! That's where we come to the next section….PGF2A and DMSO!!
These are some do's and don'ts I think is important:
1. Do up the dosage slowly!
2. Do take your time injecting!
3. Do have access to a restroom!
4. Do make sure the injection site is clean!
1. Don't inject into the ab's, lower back, forearms, and trap's(personal experience on this one)! I know Jeff rys is doing this with no lasting side effects, but I feel it is unsafe at best!
2. Don't get PGF2A near your wife or girlfriend! It can be absorbed through the skin, and will cause cramps, bleeding…etc. In women…Never get it near a woman that is pregnant!
3. Don't use this blindly…do all available research…then decide! I will in the coming weeks try another little experiment of my own. I will mix the PGF2A with DMSO and Yohimbe for spot fat reduction, and hopefully, localized growth! If anyone has tried this, or heard of anyone who has. Please post the information, and results…Thanks!!
PGF2A and DMSO
Prompted by BIGDAWG'S experiment, and my sudden lack of interest in injections !! I decided to conduct a few experiments of my own with DMSO and PGF2A…My conclusion…Injections work better, but DMSO is a welcome break!! I would spread DMSO on a 4 inch by 4-inch gauze pad, squirt ½ cc per pad, and then tape it to my Pectorals. I left it there for approximately 30 minutes. Sides were minimal at best…Somewhat heavy breathing, light headed, site becomes very warm, and once you pull the gauze off, you may see a slight rash(it will leave quickly). The site becomes rather pumped, and in the case of my Biceps, I noticed an increase in Vascularity. Now, once I pulled the gauze off my chest. I went straight to the gym. I worked my chest in a normal fashion. I became much more pumped!! I could even tell in the mirror. I did three sets of cable crossovers…MY GOD…It was Intense…veins everywhere!! For the next two days, my chest was crushed!! It felt good to be that sore again. Tried it again! in the same way the next week, no where near the same pump, or after effects!! For Biceps, I upped the dosage to 1 cc per pad, per Bicep. I achieved a good pump, and increased Vascularity. I feel you have to up the dosage a lot quicker with the DMSO method to achieve max results.
Nevertheless, that is only my opinion…if anyone else has tried this method in more depth, please post the time and results!! Remember this report, is mostly based on personal experience. Remember, not much is known about PGF2A, so take it slow. I had a GTT test done..all results were negative. I have been on for 5 weeks now. I hope this has answered many your questions, but it doesn't answer them all!! You have to decide Brother's…Is PGF2A for me?? Maybe yes, maybe no!! But, it is for Ole Ranger!!! Cause, It's All Good!! Many thanks to all those who have ventured into the unknown with this new drug, and have shared the experience!!"
Invalid Link Removed
"PGF2A Report
by Ranger
The Personals!!!
This section contains a lot of personal experiences, and side effects
with this new drug…
Big Brother Val!
According to Val pumps are INSANE! In addition, Val, as the rest of us found; needed the unrestricted use of the bathroom…Does it hurt? In Val's words, " This **** is awesome…Hurts like ****ing hell!" As Val
stayed with the injections, and SLOWLY increased the dosage, we got a report from him at the 2-week point of the cycle. Injections and dosages varied, but I will relate this as Val told it, " Hitting the arms 12 times a
day….3 in each Biceps, 3 in each Triceps, for a total of 6cc's a day. I am being burned out on injecting myself so often, especially in the Biceps. The pain is reducing now, and I do not feel sick. Still get shortness of breath, and tightness in the chest each time. There is a visible difference in growth thus far, and my body fat has dropped significally." As you can see, and as most of us found, the injections become a major burden to deal with, the benefit though, is the visible growth all of us have saw…it is a very hard choice. This was taken off the E! litefitness Board as one of Big Brother Val's Post's! I was injecting my arms 4 times a week. It went like this: Sun:..shoot/arms...... lift/rest Mon:..shoot/shoulders..lift/arms, pump/chest Tues:.shoot/shoulders..lift/back, pump/shouders Wed:..shoot/shoulders..lift/legs Thurs.shoot/arms.......lift/chest, pump/arms Fri:..shoot/arms.......lift/shoulders, pump/calves Sat:..shoot/arms.......lift/rest Then repeat. I've switched
it up a bit, and have found a lot better response... in a matter of a few days, I have new stretch marks starting on my tri's... and my arms have never felt so full. Now my lifting schedule is the same. However, I switched up the dosage on PGF2A. I read in the articles by Dharkam that you should shoot 24 hours before training a muscle... then wait 2 days after that to shoot it again. Maybe even three days if you train hard enough. I personally have found that if I shoot the muscle group the same day I train it... that my lifts go better... my pumps are abso!
lutely incredible... and I keep my pump a lot longer, as well as feel more pumped the next couple of days. Now I follow this schedule:
Sun:..shoot/arms...... lift/rest
Mon:..shoot/ARMS.......lift/arms, pump/chest
Tues:.shoot/shoulders..lift/back, pump/shouders
Wed:..shoot/shoulders..lift/legs Thurs.shoot/arms.......lift/chest, pump/arms
Fri:..shoot/SHOULDERS.......lift/shoulders, pump/calves
Sat:..shoot/arms.......lift/rest Then repeat.
Val wrote "It's only a switch of two days... but for my personal results it's really working great. On arm day, I take six cc's throughout the day. I will up the dosage coming up next week, and see how that goes. My side effects are gone... besides the odd feeling in the chest... and the intense muscle pain. Just thought I would give an update for those interested in this." I have just come off a Sustanon, Eq. cycle... and will be doing a cycle of test, Eq, and Dbol after my PGF2A run. The pain sucks, absolutely. However, I want to focus on my arms and deltas, so they can catch up. A lot harder to do on regular gear. "My poundage's are definitely affected. Not nearly as dramatic as stated in that article, though. I was curling 65 lb. dumbbells for eight reps before I started this. Now I'm curling 45 lb. dumbbells and hoping for eight. The pump is insane." "One of the great things, is that you can REALLY feel the muscle working. Really, helps to focus on that muscle group and feel it work throughout the entire range of motion. The pain factor is intense... and the muscle REALLY burns bad while training it. More so when you shoot on the same day you train it. That feeling isn't as intense if you stop shooting that muscle 24 hours before you train it." "I'm never sore after a workout the following day, but hot damn am I sore after each shot." "Well.... the muscle pain you experience is INTENSE!! Right now for example... I hit arms on my lunch break... (got the most incredible pump I have EVER had, by the way), came back, and shot in the bathroom. My arms hurt so badly right now, I can't explain it. Can't bend 'em very well, or straighten them all the way.... I have a tight feeling in the chest... Nevertheless, GODDAMN!!! This is
the biggest my arms have EVER looked!! IT'S ****IN' INSANE!! I literally cannot put on the shirt I was wearing before break... it won't stretch enough to fit on my arms!!"
Jeff rys!
After 4 to 5 weeks of PGF2A injections, Jeff reported the following to me. " I'm doing 8 shots a day at .5cc. Left Biceps, Right Biceps would equal one full cc. I am fed up with the numerous injections, and if I
can overcome being fed up with the needle, I will inject more. As for the results, ½ on arms when flexed. I did shoulders as well, and they are thicker. I did some injecting in the abs, by pulling the skin up, and
injecting. The site turned red, in a spot of around 3 square inches. I am now injecting into the muscle of the abs, but this is dangerous because you may pass through and hit an organ. I only inject abs once a week, and the site gets thick, as if a vein is iriated. It is not a vein, but it feels like it. I have dropped 11 pounds, and everyone says how good I look…. I tried lower back, and chest as well, not much results, but I think it works best if you inject in the same spot a lot more. I feel it's a good alternative to steroids…But, I don't know how safe it is."
Efigy!
Okay, here's my info: 1/2 cc in both body parts (1cc total)at a time. biceps morning, triceps noon, delt's night. this is my third day. about 5 min. after injection stinging in bodypart. about 10 min. after injection coughing and "weird feeling" in my lungs, numb lips, intense waves of pain in the body part injected. about 20-30 min. after injection slight to moderate urge to ****, not that bad though, no running to bathroom. One and ½ to two hours after injection all bad sides are gone. pleasant pump/pain in bodypart. I am noticing a big difference already! Oh
yea! I almost forgot, major chills and feeling VERY cold about 10 min. after and lasts about 30 min.
BIGDAWG!
What's up guys.. as we speak, I'm on my first dose of PGF2A. It was a little ****ed up how it happened so I will just explain from the beginning. I decided to try the DMSO method first. I guess I am just curious like that. I put 1/4 of a cc on each gauze pad and some DMSO gel. I had my wife tape the **** to my shoulders and I waited. It got warm, and I was light- headed as well. I felt weird once it was absorbing and the DMSO gets warm! I'm not sure if its that or the PGF2A, but whatever. I did 1/4 of a cc because I just wanted to test it out a little. Well, after having it on there for like 30 minutes, I said **** it, loaded another one up with 1/4 cc, and put them on my bicep's. Therefore, as I am typing this I have the pads on both areas and I am heating up rather warm. From what my boy tells me, the gel takes a little while to absorb, so I am giving it some time. I will say, my biceps's feel much-pumped right now. Kinda cool. He also told me, what he noticed was with the DMSO, its like a more "all around" growth, where as with the pin, its like a peak growth. Not all around means the whole body. It means the whole muscle you put it on. He explained to me how the vessel's work, this dudes like a medical student, so I trust him. **** I gotta ****. Hang on! Ok I am back. Goddamn did not even see that one coming! Ok I just took off the deltoid pads; it has been almost an hour now. Well it looks like a big ass rash on my deltoids now. In addition, its WARM. The biceps's are still kicking full force now. I think the dose is the thing that determines the whole **** your pants thing and all just hope I get some results. My biceps are pumped! In addition, my veins are coming out like crazy from my BI's on down. Well, I am gonna go for now. Next time I will try the inject. ****, I can't wait for that ****! Okay, after reading over the Ranger's e-mail to me a couple of times I said **** it and got up the balls to do it. I don't know why, but I was like, REALLY thinking it was going to be BAD. So after some prepping and all I had my wife stick my delts. when she injected, I didn't feel ****..nothing. in fact, I almost thought my **** was bunk..lol then I got light headed..like a paint high. then I felt a little soreness in the sites. I was waiting for the other sides and I got a couple cramps in the stomach and that was about it. now please keep in mind, I get explosive ****s all the time.. I think my body was laughing at the PGF2A, McDonalds is worse. hehe As time went on ,I began to get more sore.. like I had did a BIG set of laterals I guess. Once the soreness starts, the short breath came. not too bad though.. I only felt it when I TRIED to breathe in hard. after that all sets in, nothing else happened.. I coughed a few times but that's it. If this is what's its like ,then I shouldn't have a problem with this. Not for the results, it's supposed to give. Ranger's right on this one.. after everything I read, I was waiting for! it to be PURE HELL, but this is not the case. I will now retract my statement about the taking a **** part. I had a FULL stomach on my last inject, in fact I had just eaten a mcflurry well, at first I got a little rumble down there so I grabbed my favorite car audio magazine and went to town. the rumble was followed by some NASTY unloading, lets just say I made a swamp. **** it though, I felt lean as a mofo once it was over! the burning/pain part isn't ****, on the delts at least, I'm sure the BI's would be worse but I'm not worried about it. I guess I was
thinking it would be like REAL bad,but its not. as for injecting, I've sort of came up with my own little schedule. I figure this week I want to hit triceps and shoulders. so one-day ill do my tri's twice and shoulders once, then the next day ill change that around. this way they are getting hit twice one day and once the next day. I can't think of another way to do it without injecting like way more. The injects aren't bad! at all, I could stand it like 5 times a day, but I don't have the time to take that many 45 min ****s. Ranger, man my ****ing lips get numb now! LOL the good thing is, I'm getting used to the sides now, and they don't bother me. it did bother me last night when my wife hit a nerve in my tricep. here is a list of my experience so far..
1. the inject, no pain unless she hits the nerve.. ouch
2. slight sting on injection spot
3. begin to feel warm.. a little dizzy
4. get small cramps in stomach
5. sites get a little more sore
6. lips numb
7. HUGE ****, liquid
8. everything goes away.. chills sometimes. that's it.. it all lasts about 20-30 minutes for me and I'm done. I do this **** on my lunch break now. once one side hits, another goes away. PGF2A is not painful, it's ****ing annoying. it sucks to have to feel that way three times a day, that's why it sucks.
Ranger
Well, I guess you could say I was a little more experimental in my use with PGF2A. I wanted to see how far I could take it, and what happened, and what I could do to minimize the side effects without hindering the growth process……Well, I don't have all the answers to this one. I do know it takes dedication, as Val has showed us, and you will have to endure some pretty nasty sides from time to time….bottom line!!! The choice is yours, and yours alone!! I started out at 2.5mg's per bicep twice a day from the start. I experienced all of the aforementioned sides….Breathing, numb lips, diarrhea, hypoglycemia, muscle pain….the list goes on. However, in 2 weeks my arms grew ½ inches…doesn't sound like much? It's permanent 85growth…that's good! I did get pretty ****y at the end of the 2nd week and decided to inject calves…I injected 1cc per muscle, per leg, for a total of 4cc's or 20mg's. My GOD was the pain intense!! I couldn't walk for 30 minutes, Breathing was labored, lips complet! ely numb, mucous in my throat, and when the diarrhea came, I had to crawl to the bathroom. I was laughing and wanting to cry at the same time, but I made it(barely)! I will say this now…UP THE DOSAGE SLOWLY!!! How much? I cannot give you the answers to that, everyone will be different. BIGDAWG'S side effects are no where near that of Val', Jeff, and mine. However, take it slowly! I decided to try a very strict diet to see the effects…I only had 100 grams of Carbohydrates per day, all before lunch…low fat. The third day into this diet I was getting added side effects….light headed, headaches, cold chills, shaky. I checked my blood sugar levels the fourth day after my morning injection….49mg/dl. Yup, Hypoglycemia(low blood sugar). I quickly drank some orange juice, protein shake, and ate some Gram Crackers…the sides quickly subsided. I even made a Doctor's Appt. to have this checked further…everything came out fine…nothing! Here's what I found to work best for me…around 1 hour b! before injection, have a bowl of oatmeal, and a small protein shake. After your injection, and the sides(diarrhea) have subsided, eat 3 tablets of Glucose(chewable orange flavored…yummy!), and have a large protein shake. You can buy these over the counter and is a great sugar free Carb Booster!! This worked great for me!! I found out, and all who are using
this will agree…I have become leaner than I ever have!! As my body fat dropped, my arms and calves continued to grow, as did the rest of my body. Only at a slower pace. INJECTIONS SUCK!! You wanna grow?? Get used to the idea!! I use 28 or 29-gauge 1 inch Insulin pins. Works great Bro's! After three weeks, and all will once again agree, you will get needle phobia…heh heh heh…! That's where we come to the next section….PGF2A and DMSO!!
These are some do's and don'ts I think is important:
1. Do up the dosage slowly!
2. Do take your time injecting!
3. Do have access to a restroom!
4. Do make sure the injection site is clean!
1. Don't inject into the ab's, lower back, forearms, and trap's(personal experience on this one)! I know Jeff rys is doing this with no lasting side effects, but I feel it is unsafe at best!
2. Don't get PGF2A near your wife or girlfriend! It can be absorbed through the skin, and will cause cramps, bleeding…etc. In women…Never get it near a woman that is pregnant!
3. Don't use this blindly…do all available research…then decide! I will in the coming weeks try another little experiment of my own. I will mix the PGF2A with DMSO and Yohimbe for spot fat reduction, and hopefully, localized growth! If anyone has tried this, or heard of anyone who has. Please post the information, and results…Thanks!!
PGF2A and DMSO
Prompted by BIGDAWG'S experiment, and my sudden lack of interest in injections !! I decided to conduct a few experiments of my own with DMSO and PGF2A…My conclusion…Injections work better, but DMSO is a welcome break!! I would spread DMSO on a 4 inch by 4-inch gauze pad, squirt ½ cc per pad, and then tape it to my Pectorals. I left it there for approximately 30 minutes. Sides were minimal at best…Somewhat heavy breathing, light headed, site becomes very warm, and once you pull the gauze off, you may see a slight rash(it will leave quickly). The site becomes rather pumped, and in the case of my Biceps, I noticed an increase in Vascularity. Now, once I pulled the gauze off my chest. I went straight to the gym. I worked my chest in a normal fashion. I became much more pumped!! I could even tell in the mirror. I did three sets of cable crossovers…MY GOD…It was Intense…veins everywhere!! For the next two days, my chest was crushed!! It felt good to be that sore again. Tried it again! in the same way the next week, no where near the same pump, or after effects!! For Biceps, I upped the dosage to 1 cc per pad, per Bicep. I achieved a good pump, and increased Vascularity. I feel you have to up the dosage a lot quicker with the DMSO method to achieve max results.
Nevertheless, that is only my opinion…if anyone else has tried this method in more depth, please post the time and results!! Remember this report, is mostly based on personal experience. Remember, not much is known about PGF2A, so take it slow. I had a GTT test done..all results were negative. I have been on for 5 weeks now. I hope this has answered many your questions, but it doesn't answer them all!! You have to decide Brother's…Is PGF2A for me?? Maybe yes, maybe no!! But, it is for Ole Ranger!!! Cause, It's All Good!! Many thanks to all those who have ventured into the unknown with this new drug, and have shared the experience!!"
mattyh7688
Active member
....
Ziricote
Registered User
Source posting isn't allowed but the name of a company is in the first page of this thread...
rampage jackson
Registered User
interesting...no posts on fat reduction via transdermal...
SprtNvolcoM
On a Mission!
TLR's pgf2a, aside from being to expeinsive, is BUNK ... DONT buy it. I bought a bottle last year and completely wasted my money. I'm not some young punk who didnt know how to use it either ... so TLR, if your reading, i wantmy $ back! That being said, I just picked up two bottles of UPJOHN LABS PGF2a and have been on it for just about 10 days now. I'm not completely convinced it lives up to the hype (using IM injections 13.5mg ED (2.7mg (60iu) 5x ED)); I have a long way to go, however.
A few words of advice ...
Sides are dose dependent. Start low and build your dose up. IM injects are the way to go ... they will help induce both muscle hyprtrophy (or so its said - I have yet to see any proof of this) and destroy adipose tissue through out the entire body (IM injections will ultimitly go systematic faster than sub-q). I'm iffy on the sub-q though due to the pitting some have reported, but going to experiement with them soon. Lastly, TD applications blow - dont waste your time.
If interested, check my log ...
Invalid Link Removed
I give my first update regarding my PGF2a experience tomorrow morning. I've observed some interesting things thus far.
Sprt
spatch
Registered User
Could you explain the science of why shooting it is so painful?
southdowns
New member
hey guys im new here but have been doing alot of research on pgf2a and want to give it a go but it seems every site I go to requires a prescription any help.
awmcdon
Member
PGF-2 SUCKS!!!!
It doesn't work!!!
It gives you the sh***!!!!
You can't do anything for about two hours after taking it because you don't know if your going to have to run to the bathroom.
I'd like to see some research that says this stuff actually causes localized muscle growth......because it didn't do sh** for me...no pun intended.
The most miserable three weeks of my life..
It doesn't work!!!
It gives you the sh***!!!!
You can't do anything for about two hours after taking it because you don't know if your going to have to run to the bathroom.
I'd like to see some research that says this stuff actually causes localized muscle growth......because it didn't do sh** for me...no pun intended.
The most miserable three weeks of my life..