Rockslide
Member
Ok the TLDR main questions first . Then the full story
1. Anyone have issues with adding hcg exacerbating gyno on TRT that was previously stable. Had been off the hcg for around 6 weeks and recently added it back. Took 500 IU yesterday morning. Early and then out of absolute nowhere about 16 hours later suddenly noticed severe tenderness of previous gyno lump that had been stable for years . I have had some problems controlling estrogen on TRT but hadn’t had any issues with gyno because of it (full story below)
2. It appears that the area just above my nipple where the gyno and tenderness is is now slightly red. I have been pushing on it a little bit but not enough to make it red in itself . Has some redness of chest tissue outside of the nipple ever happened to anyone else with gyno. The concern with breast color changes is always male breast cancer but this was such sudden onset as well as extremely tender , neither of which should fit with that.
Ok the TLDR
I hopped on TRT several years ago. Was still interested in having one more kid so was put on enclomphene. Actually did pretty well on comid with levels ranging from 700 to 1200 and estrogen of around 50 to 60, After previously being around 300 with estrogen of zero before this. I did interrupt it for around eight weeks twice a year during those two years to run 11 KT, 3 ad, 1 and 4 ad . We finally got pregnant, so I decided to hop on real TRT given that there’s really no long-term safety data on Clomid in men. I’ve been relatively conservative with it only taking around 80 mg a week along with initially 250 of hCG three times a week but towards the end of the first cycle, I got lazy and started injecting 500 twice a week.
Right before I started TRT and after my last set of clomid labs while I was waiting on my appointment, I decided to run eight weeks of low-dose triumph and 4 ad. Around the last three weeks of that I had received my TRT script and started 80 mg of testosterone and the hCG. Finished up the triumph and continued on TRT for another nine weeks or so until my labs were due. I ran out of hCG about the time my labs were due. TRT labs showed testosterone of about 450. This was around two days after injecting 40 milligrams and around 500 units of hCG, although the hCG was about 10 weeks old at this point.
At that point on labs testosterone was around 450 two days after injecting and about a day and a half before my next injection of twice weekly testosterone and hCG. Estrogen was high at 122 and SHBG was low at like 6. This kind of puzzled the TRT provider with the SHBG being so low and definitely surprised me. I’m assuming that it was still low after running the oral although the oral had been out of my system for 9 weeks. They weren’t sure why the SHBG would be low but they concluded that the estrogen was so high because so much testosterone was aromatizing because SHBG was low. I somewhat agree with this, but I also think the hCG was playing a role in the high estrogen. They did not really seem to think the hCG was causing any estrogen problems which I disagree with. I had been taking 0.125 mg of anastrazole twice weekly although was prescribed 0.25 mg as preventative. Based on this, they increased the dose to 0.5 mg of estradiol three times a week. After these labs were done I also started some 11-KT at 200 mg per day TD trying to get a quick blast in for 8 weeks before my next set of labs.
I’ve continued the 80 mg a week for now although had planned on going up to around 120 a week soon when I finish up the 11 KT
HCG refill finally arrived in the mail and I injected 500 units of brand new hCG and then the gyno flared up 16 hours later out of absolute nowhere
Currently taking
200 mg 11-kt . I know that this is not causing it as I’ve run this numerous times.
80 mg a week of testosterone split twice weekly. I do not think this was causing it as it wasn’t causing problems before.
0.25 mg of Adex three times weekly which is an increase compare compared to what I was doing previously (0.125 twice weekly) based on that estrogen of over 100
Then started the hCG and this flared up. I have to assume it’s the hCG, causing massive swings of estrogen and the subsequent gyno as well as the estrogen control problems I was having before the gyno started.
Anyways, for the gyno, I basically last night as soon as it started, took 25 mg of Exemstane and started 60 mg of Ralox. Wondering how long I should wait for a response before I get a breast ultrasound , repeat labs, tell the clinic etc .
So basically if you have made it this far …..
1. Anyone else have major gyno problems strictly from hCG
2. Is the redness just outside the nipple relatively normal/ and assume it couldn’t be a cancer given that it flared up so dang quick after an hCG shot
3. Plan on doing 0.25 mg adex 3 times weekly, ralox 60 mg daily (pharm grade), and maybe 1-2 weeks of Exemstane 25 mg twice weekly as well as reducing the hCG to 250. Am I on the right track and how long before I slowly taper the serm ?
@Hyde @Smont figure both of yall have some experience here. I appreciate it if you stuck it out for the tldr
1. Anyone have issues with adding hcg exacerbating gyno on TRT that was previously stable. Had been off the hcg for around 6 weeks and recently added it back. Took 500 IU yesterday morning. Early and then out of absolute nowhere about 16 hours later suddenly noticed severe tenderness of previous gyno lump that had been stable for years . I have had some problems controlling estrogen on TRT but hadn’t had any issues with gyno because of it (full story below)
2. It appears that the area just above my nipple where the gyno and tenderness is is now slightly red. I have been pushing on it a little bit but not enough to make it red in itself . Has some redness of chest tissue outside of the nipple ever happened to anyone else with gyno. The concern with breast color changes is always male breast cancer but this was such sudden onset as well as extremely tender , neither of which should fit with that.
Ok the TLDR
I hopped on TRT several years ago. Was still interested in having one more kid so was put on enclomphene. Actually did pretty well on comid with levels ranging from 700 to 1200 and estrogen of around 50 to 60, After previously being around 300 with estrogen of zero before this. I did interrupt it for around eight weeks twice a year during those two years to run 11 KT, 3 ad, 1 and 4 ad . We finally got pregnant, so I decided to hop on real TRT given that there’s really no long-term safety data on Clomid in men. I’ve been relatively conservative with it only taking around 80 mg a week along with initially 250 of hCG three times a week but towards the end of the first cycle, I got lazy and started injecting 500 twice a week.
Right before I started TRT and after my last set of clomid labs while I was waiting on my appointment, I decided to run eight weeks of low-dose triumph and 4 ad. Around the last three weeks of that I had received my TRT script and started 80 mg of testosterone and the hCG. Finished up the triumph and continued on TRT for another nine weeks or so until my labs were due. I ran out of hCG about the time my labs were due. TRT labs showed testosterone of about 450. This was around two days after injecting 40 milligrams and around 500 units of hCG, although the hCG was about 10 weeks old at this point.
At that point on labs testosterone was around 450 two days after injecting and about a day and a half before my next injection of twice weekly testosterone and hCG. Estrogen was high at 122 and SHBG was low at like 6. This kind of puzzled the TRT provider with the SHBG being so low and definitely surprised me. I’m assuming that it was still low after running the oral although the oral had been out of my system for 9 weeks. They weren’t sure why the SHBG would be low but they concluded that the estrogen was so high because so much testosterone was aromatizing because SHBG was low. I somewhat agree with this, but I also think the hCG was playing a role in the high estrogen. They did not really seem to think the hCG was causing any estrogen problems which I disagree with. I had been taking 0.125 mg of anastrazole twice weekly although was prescribed 0.25 mg as preventative. Based on this, they increased the dose to 0.5 mg of estradiol three times a week. After these labs were done I also started some 11-KT at 200 mg per day TD trying to get a quick blast in for 8 weeks before my next set of labs.
I’ve continued the 80 mg a week for now although had planned on going up to around 120 a week soon when I finish up the 11 KT
HCG refill finally arrived in the mail and I injected 500 units of brand new hCG and then the gyno flared up 16 hours later out of absolute nowhere
Currently taking
200 mg 11-kt . I know that this is not causing it as I’ve run this numerous times.
80 mg a week of testosterone split twice weekly. I do not think this was causing it as it wasn’t causing problems before.
0.25 mg of Adex three times weekly which is an increase compare compared to what I was doing previously (0.125 twice weekly) based on that estrogen of over 100
Then started the hCG and this flared up. I have to assume it’s the hCG, causing massive swings of estrogen and the subsequent gyno as well as the estrogen control problems I was having before the gyno started.
Anyways, for the gyno, I basically last night as soon as it started, took 25 mg of Exemstane and started 60 mg of Ralox. Wondering how long I should wait for a response before I get a breast ultrasound , repeat labs, tell the clinic etc .
So basically if you have made it this far …..
1. Anyone else have major gyno problems strictly from hCG
2. Is the redness just outside the nipple relatively normal/ and assume it couldn’t be a cancer given that it flared up so dang quick after an hCG shot
3. Plan on doing 0.25 mg adex 3 times weekly, ralox 60 mg daily (pharm grade), and maybe 1-2 weeks of Exemstane 25 mg twice weekly as well as reducing the hCG to 250. Am I on the right track and how long before I slowly taper the serm ?
@Hyde @Smont figure both of yall have some experience here. I appreciate it if you stuck it out for the tldr
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