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Epiandro / 3AD cycle. Do i need a test base or can i just use enclomiphene?

504Adonis

New member
Going to run 6-8 weeks at 750 mg Epi - 150 mg 3AD. Had great gains on 3AD but adding Epiandro this time.

Can I just use enclomiphene through the cycle as a test base then ramp it up for pct? Or should I just stack a 4andro on here?

Not on trt.

Thanks!
 
Everyone reacts different. I've never used 3ad but when I've used Epiandro anywhere from 500-1200mg per day for 6-8 weeks no sides for me and a fairly easy recovery.

I've run Mtest alongside it and after
I've run Clomid alongside it
I've run Clomid plus Mtest as a PCT

I can't say I noticed a huge difference one way or another other than Clomid just giving me a little more test boost.
 
I can't remember if I had used 3AD or not, I had used gear cream which is loaded, I've used a number of variations of epiandro, androsterone, dhea etc and I have never needed anything more than a natty pct. usually I use xpg alpha gel, or M-Test with no issues.

worth noting: I have used everything from small (150mg) to mega (1100mg+) doses of epiandro and I don't think I noticed a whole lot more, if any benefit from the megadosing. 300-500mg was probably more than enough, the benefits weren't accute, they were over time and smaller prolonged doses likely gave me better gains than shorter mega doses.
 
Theres no reason to ever use enclo on cycle, ever. Use it for PCT.

Your cycle could use something that converts to estrogen, it's a preference on what you choose to use or not for that. 4andro, DHEA (preferably oral), 5-10mg dbol.
 
Your cycle could use something that converts to estrogen, it's a preference on what you choose to use or not for that. 4andro, DHEA (preferably oral), 5-10mg dbol.
the xpg dhea (I think 50mg?) was good for me.
I saw more strength gains on dermacrine, but got really itchy nipples to the point that I woke up scratching myself to bleeding, I think its the preg that I'm sensitive too, personally. i still have some dermacrine and will test it from time to time though.
 
Theres no reason to ever use enclo on cycle, ever. Use it for PCT.

Your cycle could use something that converts to estrogen, it's a preference on what you choose to use or not for that. 4andro, DHEA (preferably oral), 5-10mg dbol.
Thank you. What dosage of 4 andro would you use?
 
Theres no reason to ever use enclo on cycle, ever. Use it for PCT.

Your cycle could use something that converts to estrogen, it's a preference on what you choose to use or not for that. 4andro, DHEA (preferably oral), 5-10mg dbol.
I want to emphasize the bold part. I would rather run a cycle without any test or any test base then run a SERM through the whole thing.

For what you're proposing, I don't think you even need anything as a test base anyways. If you did want to throw one in, 4-andro or DHEA would suffice.
 
high dose epiandro never suppressed me and i have the bloodwork to prove it
That only proves it true to you, good to know tho. What was your highest dose? . My nuts DONT shrink on any cycle I've ran and I haven't came off testosterone in 6 years either, not even on tren and anadrol. Or on s23 or trestolone which were both intended for male contraceptives lol . Everyone is different tho Is my only point
 
That only proves it true to you, good to know tho. What was your highest dose? . My nuts DONT shrink on any cycle I've ran and I haven't came off testosterone in 6 years either, not even on tren and anadrol. Or on s23 or trestolone which were both intended for male contraceptives lol . Everyone is different tho Is my only point
i was around 1.5g a day of epiandro
 
i was around 1.5g a day of epiandro
Ok that's awesome, when I hear high dose I was thinking 1200mg+, I know a lot of ppl would think 900 is a lot but I'd say 600-900 is normal doses. I went to 1800mg oral a few times and I would very much compare my results to about the same as using winstrol at 50mg/day but with a tuned up feel good effect. I've always been on testosterone tho so I couldn't possibly tell on my end if there was suppression. I actually used 1200mg a day most of the summer this year 😂
 
, the benefits weren't accute, they were over time and smaller prolonged doses likely gave me better gains than shorter mega doses.
i feel the same regarding epiandro being more effective when on it long term(greater than 8 weeks) i always enjoy your posts, you have good insight . i never got much out of it from a strength or size standpoint, just maybe a little bit more muscle fullness than normal, noticeable to me but very subtle even on high oral doses and in conjunction with concurrent topical epiandro also. i have a few theories regarding epiandro that i have voiced since it came out in 2012 ish and i have presented these across multiple message boards including the old mind and muscle forums & PHF and have got criticism regarding it. i also chatted with PA also on facebook messenger maybe 2 years ago or so when i was trying to get him to make me a custom batch of oral arginine ursolic acetate.

My first theory(and most controversial) is that epiandro does not convert to DHT to a significant degree that would raise serum levels above a normal range.

2nd theory is that epiandro's mechanism of action is mediated via ER beta activation via epiandro's conversion to 3B-Androstanediol(3b diol). 3b diol has high affinity for SHBG similar to that of dht so there may be some increase in free androgens if you are using this with TRT.

3rd theory is that some of the mechanism for its effect is that epiandrosterone does convert to 7-OH derivatives like 7a and/or 7b hydroxy epiandrosterone in the liver and brain via the same mechanism that your body converts dhea to 7a/7b OH dhea and the same with pregnenolone to its 7-oh derivititives. these are well documented neurosteroids that have antiglucocorticoid and and antiestrogenic and neuroprotective effects at the tissue levels in the body and brain. there is a great overview full text read on neurosteroids on pubmed that is very interesting that i will post the link to, they play a huge role in health, and are the metabolites of your adrenal and testicular steroids and are thought to play a huge role in overall health that previously thought
 
That only proves it true to you, good to know tho. What was your highest dose? . My nuts DONT shrink on any cycle I've ran and I haven't came off testosterone in 6 years either, not even on tren and anadrol. Or on s23 or trestolone which were both intended for male contraceptives lol . Everyone is different tho Is my only point
They say acne is one of the most common sides of anabolics and I don't recall ever getting acne from a cycle.
 
They say acne is one of the most common sides of anabolics and I don't recall ever getting acne from a cycle.
Ya, I'd say acne, gyno and balding in that order. Almost everyone gets one of the 3. When you don't get any of the 3 you turn into Jay Cutler lol. Originaly I would get acne and gyno, now I get no acne and only occasional gyno flare ups. I definitely think we can eventually adjust as I have seemed too.
i feel the same regarding epiandro being more effective when on it long term(greater than 8 weeks) i always enjoy your posts, you have good insight . i never got much out of it from a strength or size standpoint, just maybe a little bit more muscle fullness than normal, noticeable to me but very subtle even on high oral doses and in conjunction with concurrent topical epiandro also. i have a few theories regarding epiandro that i have voiced since it came out in 2012 ish and i have presented these across multiple message boards including the old mind and muscle forums & PHF and have got criticism regarding it. i also chatted with PA also on facebook messenger maybe 2 years ago or so when i was trying to get him to make me a custom batch of oral arginine ursolic acetate.

My first theory(and most controversial) is that epiandro does not convert to DHT to a significant degree that would raise serum levels above a normal range.

2nd theory is that epiandro's mechanism of action is mediated via ER beta activation via epiandro's conversion to 3B-Androstanediol(3b diol). 3b diol has high affinity for SHBG similar to that of dht so there may be some increase in free androgens if you are using this with TRT.

3rd theory is that some of the mechanism for its effect is that epiandrosterone does convert to 7-OH derivatives like 7a and/or 7b hydroxy epiandrosterone in the liver and brain via the same mechanism that your body converts dhea to 7a/7b OH dhea and the same with pregnenolone to its 7-oh derivititives. these are well documented neurosteroids that have antiglucocorticoid and and antiestrogenic and neuroprotective effects at the tissue levels in the body and brain. there is a great overview full text read on neurosteroids on pubmed that is very interesting that i will post the link to, they play a huge role in health, and are the metabolites of your adrenal and testicular steroids and are thought to play a huge role in overall health that previously thought
I don't think your completely wrong and I also have always thought that very little epiandro actually converts to DHT. I think that Epiandro doesn't have a ton of conversion to DHT, but instead to DHT metabolites (which I definitely know it does convert to the metabolites) DHT itself is a highly anabolic active hormone but the metabolites are not. Lots of DHT metabolites convert into neuro steroids. While neurosteroids don't build muscle, they do increase CNS activity and force production as well as increase energy and drive. So a small amount of DHT and a lot of DHT metabolites is what it looks like to me.

Now let's look at what epiandrosterone seems to do to most ppl. High dose epiandro gives me some strength gains, positive gym aggression, some increase in sex drive, and muscle hardness if I'm already lean. But I'd say it does very little to build muscle.

That's right on par with lots of CNS activity with only a small amount of anabolic activity.

People who get more DHT conversion then others would probably be the people experiencing some shutdown, dry joints and maybe hair thinning. The people getting all the CNS activity are the ones who aren't getting any negative side effects only really making strength gains but not building any muscle.

I know there's a lot of speculation in there but there's also a lot of Truth to it as well, I'm just trying to connect the dots like you are
 
They say acne is one of the most common sides of anabolics and I don't recall ever getting acne from a cycle.
the only time i would get acne is when i would stop taking substances cold turkey. occasional puffy nipples and hair loss has been progressing since i was 19 but sped up on trt over the past 8 months. i did a month by month propecia log back in 2009-2010 on elitefitness but the sides were to bad for me to continue it. unfortunate because it really worked well for me
 
the only time i would get acne is when i would stop taking substances cold turkey. occasional puffy nipples and hair loss has been progressing since i was 19 but sped up on trt over the past 8 months. i did a month by month propecia log back in 2009-2010 on elitefitness but the sides were to bad for me to continue it. unfortunate because it really worked well for me
If you started losing hair at 19 and you aren't bald yet, then you must have been using something. There is no way you should still have hair. Are you using topical finasteride?
 
If you started losing hair at 19 and you aren't bald yet, then you must have been using something. There is no way you should still have hair. Are you using topical finasteride?
i still have a decent amount of hair, started receding at the temple region 25 years ago, now the front center is thinning and receding(i have a five head now. lol) and have a small bald spot on the top back that is noticeable to family and friends now and slowly getting bigger. everyone goes bald at a different rate. i think i will probably be mostly bald by early 70's when the bald spot at the back catches up with the receding hairline in the front. everyone in my family goes bald on both sides including 2 older brothers who also have receding hairlines
 
i still have a decent amount of hair, started receding at the temple region 25 years ago, now the front center is thinning and receding(i have a five head now. lol) and have a small bald spot on the top back that is noticeable to family and friends now and slowly getting bigger. everyone goes bald at a different rate. i think i will probably be mostly bald by early 70's when the bald spot at the back catches up with the receding hairline in the front. everyone in my family goes bald on both sides including 2 older brothers who also have receding hairlines
Are you using anything? It's just surprising that someone who started balding at 19 isn't bald 25 years later if they aren't using minoxidil and/or some version of finasteride.

When you used finasteride, did you use 5mg or 1mg? I believe years ago people used to use 5mgs where sides used to kick in. Now they use 1mg which seems to work and keep sides away (for most people at least). Some people still use 5mgs but mostly for prostate issues now.
 
Are you using anything? It's just surprising that someone who started balding at 19 isn't bald 25 years later if they aren't using minoxidil and/or some version of finasteride.

When you used finasteride, did you use 5mg or 1mg? I believe years ago people used to use 5mgs where sides used to kick in. Now they use 1mg which seems to work and keep sides away (for most people at least). Some people still use 5mgs but mostly for prostate issues now.
Oddly enough, my hair line receded a little bit in my early 20's and never got worse. I would say now at 40 my hair is a little bit thinner but I absolutely would say I have a thick full head of hair. I'm the only person who probably notices that my hairline receded a little bit because I am hyper focused on stuff like that. But again it hasn't really receded since my early twenties and I know that doesn't make any sense. My father is 72 full head of hair, it's thinned a little bit still full. Both my older male relatives my dad's age have full heads of hair.

Now figure this one out. My generation, excluding me, my brother, and 3 of my 4 male cousins are all bald. Two of my cousins and my brother are younger than me and have never used anabolics. I'm older than them and have been using stuff on and off for years and I still have the full head of hair lol.

I've used a DHT blocking shampoo on 3 cycles when I was younger but other then that, I do nothing for hair.
 
Oddly enough, my hair line receded a little bit in my early 20's and never got worse. I would say now at 40 my hair is a little bit thinner but I absolutely would say I have a thick full head of hair. I'm the only person who probably notices that my hairline receded a little bit because I am hyper focused on stuff like that. But again it hasn't really receded since my early twenties and I know that doesn't make any sense. My father is 72 full head of hair, it's thinned a little bit still full. Both my older male relatives my dad's age have full heads of hair.

Now figure this one out. My generation, excluding me, my brother, and 3 of my 4 male cousins are all bald. Two of my cousins and my brother are younger than me and have never used anabolics. I'm older than them and have been using stuff on and off for years and I still have the full head of hair lol.

I've used a DHT blocking shampoo on 3 cycles when I was younger but other then that, I do nothing for hair.
you are so lucky with minimal loss at 40 given your family history, i feel like i have a young face except for my hairline, and a salt and pepper beard that is becoming more salt than pepper. Another 5 years i think the whole top of my head will be pretty gray.
 
Oddly enough, my hair line receded a little bit in my early 20's and never got worse. I would say now at 40 my hair is a little bit thinner but I absolutely would say I have a thick full head of hair. I'm the only person who probably notices that my hairline receded a little bit because I am hyper focused on stuff like that. But again it hasn't really receded since my early twenties and I know that doesn't make any sense. My father is 72 full head of hair, it's thinned a little bit still full. Both my older male relatives my dad's age have full heads of hair.

Now figure this one out. My generation, excluding me, my brother, and 3 of my 4 male cousins are all bald. Two of my cousins and my brother are younger than me and have never used anabolics. I'm older than them and have been using stuff on and off for years and I still have the full head of hair lol.

I've used a DHT blocking shampoo on 3 cycles when I was younger but other then that, I do nothing for hair.
It's just the luck of the draw. But what you're saying is not completely unheard of. Some people get a matured hairline and then they don't lose anymore hair at all. It does happen. But the fact that your dad has a full head of hair is a good sign!
 
I am getting a grey beard and some grey in my hair tho 😔. I'm not ready for Grey's!
The guys in my family don't seem to get very gray until much later in life. My dad is in his 70s and has a little bit of gray now but not much. I don't have any gray at all.
 
Are you using anything? It's just surprising that someone who started balding at 19 isn't bald 25 years later if they aren't using minoxidil and/or some version of finasteride.

When you used finasteride, did you use 5mg or 1mg? I believe years ago people used to use 5mgs where sides used to kick in. Now they use 1mg which seems to work and keep sides away (for most people at least). Some people still use 5mgs but mostly for prostate issues now.
i am not using anything right now, back in 2001-2003 i used nizoral shampoo because that was the only otc bro science thing available besides topical minox. then in january of 2009 i started finasteride 1mg(non generic) the stuff was very expensive at the time, i think around $80-100 a month from a legit pharmacy from a script from my primary. i definitely noticed my hair was thicker by about 6 months and scalp was not tight and inflamed anymore and the skin seemed like it was thicker and had more subcutaneous fat on my scalp. by 1 year everyone noticed how nice my hair looked. i grew my hair longer down to shoulder length and only had 1 haircut in 16 months during this. the sides were not tolerable for me, i had the worst aching pain in my legs, i felt tired all the time, my armpits smelled like hot garbage 5 minutes out of the shower, my face was puffy, and i lost some vascularity. strength and sex drive was unchanged. i had a weird aversion to arugula which i normally love while taking this .within about a week of stopping finasteride i started to feel better around may of 2010. i did not notice a huge shedding but i would say by a year later i was back at baseline. my pcp offered to put me on avodart when i told him the sides i had but i refused
 
i am not using anything right now, back in 2001-2003 i used nizoral shampoo because that was the only otc bro science thing available besides topical minox. then in january of 2009 i started finasteride 1mg(non generic) the stuff was very expensive at the time, i think around $80-100 a month from a legit pharmacy from a script from my primary. i definitely noticed my hair was thicker by about 6 months and scalp was not tight and inflamed anymore and the skin seemed like it was thicker and had more subcutaneous fat on my scalp. by 1 year everyone noticed how nice my hair looked. i grew my hair longer down to shoulder length and only had 1 haircut in 16 months during this. the sides were not tolerable for me, i had the worst aching pain in my legs, i felt tired all the time, my armpits smelled like hot garbage 5 minutes out of the shower, my face was puffy, and i lost some vascularity. strength and sex drive was unchanged. i had a weird aversion to arugula which i normally love while taking this .within about a week of stopping finasteride i started to feel better around may of 2010. i did not notice a huge shedding but i would say by a year later i was back at baseline. my pcp offered to put me on avodart when i told him the sides i had but i refused
Wow. I'm using the topical finasteride and I don't have any of those side effects or any sides at all. Not sure if topical makes a difference or not though.
 
Wow. I'm using the topical finasteride and I don't have any of those side effects or any sides at all. Not sure if topical makes a difference or not though.
Topical has less risks for side effects but finastride has some potential for nasty side effects. If you have been using it without issues your gtg. I won't use finastride ever, id rather not find out of I'm one of the people who gets the sides or post finastride syndrome, and if my hair does start to go il pay for a transplant 😂. Ya I'm vain
 
Topical has less risks for side effects but finastride has some potential for nasty side effects. If you have been using it without issues your gtg. I won't use finastride ever, id rather not find out of I'm one of the people who gets the sides or post finastride syndrome, and if my hair does start to go il pay for a transplant 😂. Ya I'm vain
I'm with you. I already have the money put aside for a hair transplant. I lost hair around the hairline but nothing in the back.

Regarding finasteride, I thought the same way you did. I was nervous as hell of the side effects, which is why it took me so long to start it. Then I spoke with several people I know who were on it and they all said they had no sides and it worked well for them. So I jumped on the topical and had no side effects at all. I tracked my bloodwork too, just to make sure there weren't any hormonal sides I wasn't picking up on but no differences showed up.

Everyone has to make their own decisions when it comes to this stuff though. I think the majority of people who use finasteride won't have side effects, but if you're one of the few that do, it's going to really suck based on what I've read.
 
damn you guys covered a lot of ground in here

i never got much out of it from a strength or size standpoint, just maybe a little bit more muscle fullness than normal, noticeable to me but very subtle even on high oral doses and in conjunction with concurrent topical epiandro also.

My first theory(and most controversial) is that epiandro does not convert to DHT to a significant degree that would raise serum levels above a normal range.

Ya, I'd say acne, gyno and balding in that order. Almost everyone gets one of the 3. When you don't get any of the 3 you turn into Jay Cutler lol. Originaly I would get acne and gyno, now I get no acne and only occasional gyno flare ups. I definitely think we can eventually adjust as I have seemed too.

I don't think your completely wrong and I also have always thought that very little epiandro actually converts to DHT. I think that Epiandro doesn't have a ton of conversion to DHT, but instead to DHT metabolites (which I definitely know it does convert to the metabolites) DHT itself is a highly anabolic active hormone but the metabolites are not. Lots of DHT metabolites convert into neuro steroids. While neurosteroids don't build muscle, they do increase CNS activity and force production as well as increase energy and drive. So a small amount of DHT and a lot of DHT metabolites is what it looks like to me.

Now let's look at what epiandrosterone seems to do to most ppl. High dose epiandro gives me some strength gains, positive gym aggression, some increase in sex drive, and muscle hardness if I'm already lean. But I'd say it does very little to build muscle.

I am getting a grey beard and some grey in my hair tho 😔. I'm not ready for Grey's!

I do feel like epi helped me hold mass on cuts. I agree with pretty much everything you guys said. my drive in the gym and libido go up. Also when I'm on epiandro, I have massive lethargy which I think is a result of more intense lifting sessions followed by intense recovery. I always said it felt like a growing puppy or a teenage kid who hits the wrestling mat for 3 hours then sleeps for 12 hours. then wakes up stronger and leaner tomorrow.

DHT is a hard one. I definitely have some thinning on that back top spot I think its called the vertex area. I saw some hair in my hands back in 2019 when my stress was insane running a second business (gym) and then it stopped, then I saw it again when doing some epi runs. However, my little brother has thinned more drastically than I have in that area (we have no family pattern of baldness so its just he and I) and he has not used any PED's ever in his life. so I can't tell you for sure whether my own thinning is from supplements or just normal life. Its pretty mild, its there, but its mild. if it were to stop at its current situation I'd be pretty happy with this head of hair in 10-20 years.

the only side effect, aside from possibly shedding, from epiandro that I ever see is my risk for anxiety increases quite a bit. I haven't really found a good cure to curtail that so I've laid off epi for about a year now. every once in a while I'll try to bring back small doses but if I get hit with an anxiety attack I shy away from it cause its just not worth that level of discomfort.

I've only got itchy nipples from pregnenolone I think because it got it pretty bad from dermacrine, which has it, but not xpg dhea, which does not.

at 43 years old ped's started around age 40, have mostly been epiandro with a little androsterone (ultra hard is a favorite of mine), and 2 runs of VAR. I've basically been PED free in all of 2025 and I think its insane how much lean mass I hold right now. I do think that the PED's helped me push through to create new and that I last very little, if any, of my gains when coming off.
 
when I first met my wife her hair cutter guy (with possibly the greast name ever. a gay dude named Hung. can't get better than that) told her I had the type of hair that thins. WTF! LOL. I was like F you buddy, there's no male baldness anywhere in my family tree! but here I am 8-10 years later with a little thinning so again, hard to say if its the supplementation or just life. I have some greys, not a lot. but they aren't limited to my head. a couple in the beard, chest etc.
 
the only side effect, aside from possibly shedding, from epiandro that I ever see is my risk for anxiety increases quite a bit. I haven't really found a good cure to curtail that so I've laid off epi for about a year now. every once in a while I'll try to bring back small doses but if I get hit with an anxiety attack I shy away from it cause its just not worth that level of discomfort.
epiandro does act as a gaba receptor antagonist i believe, non direct mechanism i think


neurosteroids are quite interesting, even more so to me than traditional/designer AAS

best feeling one on the market for me is pregnenolone(P5) transdermal in salvo by alpha gainz and iconic formulations neuro p5. at 75mg transdermal a day i get a increased sense of wellbeing, decreased cold intolerance, and skin plumpness and hydration on my face made me look 5 years younger. was one of the most interesting findings of a supplement i picked up on a whim maybe 6 years ago or so that was reproduced on multiple purchases. oral pregnenolone had little effect, even went up to 400mg oral but it kind of killed my sex drive and erectile dysfunction
 
75mg transdermal a day i get a increased sense of wellbeing
I think I get a little bit of that from everything I've tried (dermacrine, xpg epi, xpg dhea, ultra hard, ultra epi, gear cream, etc) but by far, the #1 good vibes product for me was ultra hard and I think that was the androsterone.
 
Hey Lanky, do you run pregnenolone year round? Just curious because I like the idea of looking 5 years younger brother man
 
Hey Lanky, do you run pregnenolone year round? Just curious because I like the idea of looking 5 years younger brother man
i don't run transdermals year round besides my TRT of androgel. currently i just started running androsterone in salvo yesterday and have 3 bottles, i was going to wait until after christmas and my next bloodwork for my urologist but could not wait .i will probably be running transdermal pregnenolone soon. i have some raw progesterone and pregnenolone powder and some bottles of plain salvo that i am going to be making my own batch of a mixture of the two. i did an experiment a year ago and ran progesterone in salvo and had some good results with the skin on my face similar to pregnenolone. salvo seemed to hold a good amount of progesterone without crashing. i cant remember how many grams i added to the bottle(probably around 3 grams or more) but i remember it dissolved easily in a warm water bath. i will have to look up my old posts here...pregnenolone really shines transdermally. i may have to experiment to see if salvo will hold more than 25mg/ml pregnenolone and if it will remain shelf stable without crashing if sitting untouched for over a month or so. Rob from iconic/alpha gainz might have some insight in his formulation of this product
 
here is my old post for progesterone in salvo:

"thank you so much for thinking of me, it is micronized progesterone that i am using for the experiment, i have 10g to work with only cost 50 bucks from epothex, and the salvo bottle only was 20 ish w shipping from DPS. i have read up on it and the barriers for transdermal use regarding its need for high dose for efficacy. i think LogP for progesterone is 3.9 so its right on the edge, even the progesterone does not have great kinetics for getting into circulation hopefully some of the metabolites at the application site may have the ability for better permeability w repeated dosing at the same application site. some of the research i have read is that even though serum progesterone levels may not be that elevated compared to baseline, local tissue levels not at the site of application may be significantly higher than normal suggesting better kinetics than previously thought not including the the downstream metabolites. My interest in neurosteroids all started with pregnenolone in salvo that i had great experiences with a few years back. i dont know why my DM is not working, someone else said the same thing a week or two ago, i will try and play around with my settings. i will give it a shot with 2 grams and see how it goes. i can always send you the remaining 8 to play around with if you want to experiment also. neurosteroids are one of the most overlooked niche market in the bodybuilding and general health/longevity market. most of the neurosteroids products out there are pretty cookie cutter, no one thinks outside the box for delivery methods. usually it is the same old capsule, or maybe it your lucky it is in a liquid suspension of ethanol, or maybe some form of lecithin."
 
epiandro does act as a gaba receptor antagonist i believe, non direct mechanism i think


neurosteroids are quite interesting, even more so to me than traditional/designer AAS

best feeling one on the market for me is pregnenolone(P5) transdermal in salvo by alpha gainz and iconic formulations neuro p5. at 75mg transdermal a day i get a increased sense of wellbeing, decreased cold intolerance, and skin plumpness and hydration on my face made me look 5 years younger. was one of the most interesting findings of a supplement i picked up on a whim maybe 6 years ago or so that was reproduced on multiple purchases. oral pregnenolone had little effect, even went up to 400mg oral but it kind of killed my sex drive and erectile dysfunction
Anything that effects your CNS can increase anxiety regardless of the gaba thing. Steroids and anabolics in general all have the ability to increase anxiety too as far as I'm aware
 
Anything that effects your CNS can increase anxiety regardless of the gaba thing. Steroids and anabolics in general all have the ability to increase anxiety too as far as I'm aware
any suggestions on how to combat that? I have a ton of epi I just don't really use anymore cause anxiety attacks randomly hitting for no reason just aren't worth it.
 
I love epi but I have to piss hourly on that stuff. Driving down the road and looking to stop and use the bathroom is a problem. 🤣
 
any suggestions on how to combat that? I have a ton of epi I just don't really use anymore cause anxiety attacks randomly hitting for no reason just aren't worth it.
I don't think anything is going to stop that. Anxiety is a big part of the ped world and many ppl don't acknowledge it, it's mostly the physical symptoms of anxiety. I'm hoping nebivolol (beta blocker )is going to be a savior for me. I've yet to use it but it's actions make it lower resting heart rate, lower blood pressure and reduce anxiety. I wake up with 85-90bpm heart rate ready to fight lol, anxiety is my middle name lol
 
epi never caused anxiety for me, maybe intermittently a little bit more amped up than normal. i remember when i started HRT i took 2.5g a day of epi that i had left over for a few weeks, and a few days at work i felt like a was stomping around and easily frustrated for little things. that sensation was not everyday. i remember when one of the computer and monitor cables were tangled and i was trying to untangle them and wanted to smash the computer
 
It’s weird, when I’m on cycle I feel like a god, very confident, head strong etc. but on the flip side every small inconvenience really bothers me, such as the Greek yoghurt lid flipping back onto the pot when I’m trying to scoop some yoghurt out. I’ll be cursing it out in my head. So strange.
When I’m not on cycle something like that I would genuinely find humorous.

Luckily don’t get the anxiety though.
 
Anxiety is a big part of the ped world and many ppl don't acknowledge it, it's mostly the physical symptoms of anxiety. I'm hoping nebivolol (beta blocker )is going to be a savior for me. I've yet to use it but it's actions make it lower resting heart rate, lower blood pressure and reduce anxiety. I wake up with 85-90bpm heart rate ready to fight lol, anxiety is my middle name lol
I don't really have HR or BP issues. the only time my bp is elevated is if I'm drinking (well, if I drank yesterday). My resting HR started to get into the 60s after taking a year off of focused conditioning work but I got that back down to 47-57 so I'm happy there. If I get any anxiety its more like a perceived shortness of breath type issue. the body is functioning fine but the brain things you're dying, lol.

and I say perceived because it is perceived, nothing changes, its just all the sudden hyper awareness of every breath, the size of your tongue, etc lol. it's honestly embarrasing and I hadn't had to deal with it in nearly a decade but every once in a while it randomly hits me and i have to just try to ignore it or distract myself.
 
Luckily don’t get the anxiety though.
I never did until 2016 when I think I just had more stressors in my life than my brain could handle. I walked through my life seemingly perfectly fine. was shredded to the bone, hitting the gym regular, work was going great. getting hardly any sleep though cause big life move etc and it all caught up to me and put me in the hospital briefly thinking I was having a heart attack lol 😂 😂 😂 I read up on meds for it and decided to never try them cause I they can cause some long term wiring changes I didn't want so I just dealt with it and rubbed some dirt on it, eventually got tougher and rarely see it anymore. BUT I'm also aware of it enough to not want to intentionally trigger it cause it's fuckin' miserable.
 
I don't really have HR or BP issues. the only time my bp is elevated is if I'm drinking (well, if I drank yesterday). My resting HR started to get into the 60s after taking a year off of focused conditioning work but I got that back down to 47-57 so I'm happy there. If I get any anxiety its more like a perceived shortness of breath type issue. the body is functioning fine but the brain things you're dying, lol.

and I say perceived because it is perceived, nothing changes, its just all the sudden hyper awareness of every breath, the size of your tongue, etc lol. it's honestly embarrasing and I hadn't had to deal with it in nearly a decade but every once in a while it randomly hits me and i have to just try to ignore it or distract myself.
I don't have BP issues either but my anxiety makes my heart rate go up for sure, my anxiety is always coupled with adrenaline and that fight or flight feeling. When I feel it racing is when it actually starts to mess with my head. Nebivolol blocks adrenaline and noradrenaline so for me it's a possible solution. At least worth me exploring. Oddly enough, when I use to drink, I never had anxiety. Ever. I kinda use to think anxiety was bullshit lol. Drinking was always a bandaid on my anxiety, but gear definitely makes it worse sometimes, not always, but the more I use stuff the more I realize. Early on I didn't really notice it because I was so focused on other things. Now that I'm aware of it, it seems to be worse, and it lingers.
 
I never did until 2016 when I think I just had more stressors in my life than my brain could handle. I walked through my life seemingly perfectly fine. was shredded to the bone, hitting the gym regular, work was going great. getting hardly any sleep though cause big life move etc and it all caught up to me and put me in the hospital briefly thinking I was having a heart attack lol 😂 😂 😂 I read up on meds for it and decided to never try them cause I they can cause some long term wiring changes I didn't want so I just dealt with it and rubbed some dirt on it, eventually got tougher and rarely see it anymore. BUT I'm also aware of it enough to not want to intentionally trigger it cause it's fuckin' miserable.
I do know that rediculous feeling like your going to die, I usually have to give myself a quick pep talk. I've been in my car driving and had to look myself in the mirror and say.... knock it off! 😂
 
It’s weird, when I’m on cycle I feel like a god, very confident, head strong etc. but on the flip side every small inconvenience really bothers me, such as the Greek yoghurt lid flipping back onto the pot when I’m trying to scoop some yoghurt out. I’ll be cursing it out in my head. So strange.
When I’m not on cycle something like that I would genuinely find humorous.

Luckily don’t get the anxiety though.
Its weird, I've always been very, very confident. On cycle most of the time I just feel good. I generally feel good on cycle, if anything gear can make me sad a lot easier than it can make me angry, I never feel angry because of it. Especially if it's high testosterone and my estrogen is good. It's usually when I throw in a oral or tren ace. Fast acting gear seems to give me acute anxiety. It's not all the time. Tren makes me sad and anxious in short bursts.

But I also suffer from anxiety as a whole I wish I didn't get anxiety lol. It's just crazy to me because my life used to be the polar opposite of this I was out partying 24/7 living like an absolute crazy person, skydiving, bungee jumping, fighting and just living balls to the wall. Fast forward quitting drinking and being 40, I like to sit on the couch and pet my cats lol. Being out in public places makes me want to curl up in a ball or go home.

But for fun I still go box and grapple and lift ect, it doesn't make sense lol
 
adrenaline and that fight or flight feeling.
yeah when I was having the issues back in 2016 I decided since it felt like a massive surge of adrenaline racing through my body I started turning on the angriest metal music I could find to try to wire my body to fight instead of flight and tbh with you I think it worked. it became my go to solution any time I had an attack.

At least worth me exploring. Oddly enough, when I use to drink, I never had anxiety. Ever. I kinda use to think anxiety was bullshit lol. Drinking was always a bandaid on my anxiety,

I agree with all of that, same- I don't think a drink has ever given me anxiety but I have noticed if I had been drinking say last night, and took bp today, it would be higher than if I had nothing to drink today, and took bp tomorrow.
 
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