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The Return of a King ..... Kronos 11-KT, at Apex-Alchemy!!!

Start at 1ml and adjust as needed. The higher you go the more androgenic it gets. Lower dosing is great for cortisol manipulation, and fat loss. [But] as you go higher and higher in dosing, the more likely you're going to see side effects of some sort. Like sore joints etc.

Take your time finding your personal sweet spot. Keeping goals in mind, if you're just trying to hold mass during a diet, you may need less than you think to get awesome results. Or if you're trying to get stronger and maybe add some mass, possibly 2-3 mls is going to work better.

  • 11-KT activates the androgen receptor similarly to testosterone, but without triggering estrogen receptor pathways.
  • In lab studies using MCF-7 cells (a breast cancer cell line), 11-KT inhibited cell proliferation when androgen receptors were present, suggesting potent androgenic effects.
 
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11-ketotestosterone (11-KT) and cortisol share a common enzymatic pathway, and their interaction can influence stress response, metabolism, and even body composition.
Both 11-KT and cortisol are synthesized from 11β-hydroxylase (CYP11C1) activity.

🧬 Cortisol Suppression via HSD11B Inhibition​

One of the most intriguing effects of 11-KT in humans and other vertebrates is its inhibition of HSD11B1, the enzyme that converts inactive cortisone into active cortisol:

  • By blocking this conversion, 11-KT can lower cortisol levels, reducing systemic stress response
  • This mechanism is believed to help mobilize stubborn fat stores, especially in the lower back and abdomen
This makes 11-KT particularly interesting to bodybuilders and biohackers seeking lean muscle gains without water retention or estrogenic effects.
 
Im sure it has been discussed before but at al low dose 50-100, would this cause shutdown. Trying to see if I could avoid shutdown or messing with hpta but gain some benefit?
 
11-ketotestosterone (11-KT) and cortisol share a common enzymatic pathway, and their interaction can influence stress response, metabolism, and even body composition.
Both 11-KT and cortisol are synthesized from 11β-hydroxylase (CYP11C1) activity.

🧬 Cortisol Suppression via HSD11B Inhibition​

One of the most intriguing effects of 11-KT in humans and other vertebrates is its inhibition of HSD11B1, the enzyme that converts inactive cortisone into active cortisol:

  • By blocking this conversion, 11-KT can lower cortisol levels, reducing systemic stress response
  • This mechanism is believed to help mobilize stubborn fat stores, especially in the lower back and abdomen
This makes 11-KT particularly interesting to bodybuilders and biohackers seeking lean muscle gains without water retention or estrogenic effects.
 
Im sure it has been discussed before but at al low dose 50-100, would this cause shutdown. Trying to see if I could avoid shutdown or messing with hpta but gain some benefit?

It is Minimally suppressive. IMO, Very Minimally.
Personally, if it were any less suppressive, I would deem it not suppressive (and over the years, I've been kinda known as a harm reduction guy).

This is a Great product, and I'm delighted that we have been able to bring it back, as are a Lot of other people.
 
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It is Minimally suppressive. IMO, Very Minimally.
Personally, if it were any less suppressive, I would deem it not suppressive (and over the years, I've been kinda known as a harm reduction guy).

This is a Great product, and I'm delighted that we have been able to bring it back, as are a Lot of other people.
Im all for the harm reduction. Just don't want to mess with hpta anymore!
 
Im sure it has been discussed before but at al low dose 50-100, would this cause shutdown. Trying to see if I could avoid shutdown or messing with hpta but gain some benefit?
I wouldn't worry about 50mg. If I was running 200 and not on TRT or anything else then I'd definitely call it a cycle and run pct.

Let me reword that, if I was gonna run a bottle a week and not on TRT...... Wait, let me try again.

I'm probably going to run a bottle a week for 6 weeks, good thing I'm on TRT.

Ya that's better 🤣
 
Is this the same carrier as all of the other products? I only ask because the last TD I used left me super scaley and itchy even with rotating and lotion. Not an Apex product fwiw
 
Is this the same carrier as all of the other products? I only ask because the last TD I used left me super scaley and itchy even with rotating and lotion. Not an Apex product fwiw

It is the same carrier as our other products.
 
Is this the same carrier as all of the other products? I only ask because the last TD I used left me super scaley and itchy even with rotating and lotion. Not an Apex product fwiw

It's a great carrier, in most people's options. I doubt you'd have an issue with it.
 
I personally get just gradual leaning at 100 mg a day and don’t feel any suppression.

At 150-200 mg /day I get noticeable recomp … seems like I won’t add fat in a surplus and hold on to muscle better in a deficit and get a little stronger. I also lean out and get much more vascular much quicker . I get nice pumps in the gym but I am spared the nasty calf pumps in cardio which is nice

75 mg of oral 3ad and 150-200 mg 11kt is easy to recover from by just hopping back on my 12.5 enclomiphene trt.

I keep telling myself I’m going to try 300 mg daily some day now that I just started test cyp trt. Might be hard on the joints at that dose though
 
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I personally get just gradual leaning at 100 mg a day and don’t feel any suppression.

At 150-200 mg /day I get noticeable recomp … seems like I won’t add fat in a surplus and hold on to muscle better in a deficit and get a little stronger. I also lean out and get much more vascular much quicker . I get nice pumps in the gym but I am spared the nasty calf pumps in cardio which is nice

75 mg of oral 3ad and 150-200 mg 11kt is easy to recover from by just hopping back on my 12.5 enclomiphene trt.

I keep telling myself I’m going to try 300 mg daily some day now that I just start test cyp trt. Might be hard on the joints at that dose though

Let us know if you do!
 
Much more likely to be willing to push it high now that it seems less likely that this is going to go away like we thought it would . It’s such a good mild compound that gives really good results without taxing the health too much
 
Much more likely to be willing to push it high now that it seems less likely that this is going to go away like we thought it would . It’s such a good mild compound that gives really good results without taxing the health too much
I’m also VERY glad that it seems 11-keto will be around for longer… I was already dreading my cutting next summer without it in case it was pulled off the market 😂
 
I’m also VERY glad that it seems 11-keto will be around for longer… I was already dreading my cutting next summer without it in case it was pulled off the market 😂
I'm 4 weeks into a cut right now and I'm super tempted to add this product in for the last 6 weeks or so should it arrive in a timely fashion.
 
I'm located in Canuckistan so hopefully the customs agents don't decide to keep my Kronos for themselves in order to "protect" me from such a dangerous product.
Same here brother, I already ordered 60ml and I don’t think I’ll have a problem but if I do I’ll lyk. Your from BC aswell?
 
I personally get just gradual leaning at 100 mg a day and don’t feel any suppression.

At 150-200 mg /day I get noticeable recomp … seems like I won’t add fat in a surplus and hold on to muscle better in a deficit and get a little stronger. I also lean out and get much more vascular much quicker . I get nice pumps in the gym but I am spared the nasty calf pumps in cardio which is nice

75 mg of oral 3ad and 150-200 mg 11kt is easy to recover from by just hopping back on my 12.5 enclomiphene trt.

I keep telling myself I’m going to try 300 mg daily some day now that I just started test cyp trt. Might be hard on the joints at that dose though
I'm not on TRT and would like to maintain my healthy levels. 75 mg of oral 3ad and 150-200 mg 11kt sounds good. I have been thinking about 8 weeks solo epiandro w enclo PCT but was worried about the anxiety some report because I have high Cortisol- according to my latest labs. The 11kt would keep that in check. What has been your experience? What would pre - T you run?
 
Same here brother, I already ordered 60ml and I don’t think I’ll have a problem but if I do I’ll lyk. Your from BC aswell?
I'm located in Alberta. I find that most packages have been making it through fine although I've generally been careful to avoid banned items most of the time. The thing that gets me is the ludicrous rule of only being able to import 3 months supply of a product at a time as that largely removes a lot of the bigger bottle sizes from being an option and can make it hard to take advantage of sales without having to pay more shipping for multiple packages.
 
I'm not on TRT and would like to maintain my healthy levels. 75 mg of oral 3ad and 150-200 mg 11kt sounds good. I have been thinking about 8 weeks solo epiandro w enclo PCT but was worried about the anxiety some report because I have high Cortisol- according to my latest labs. The 11kt would keep that in check. What has been your experience? What would pre - T you run?

Everybody is different of course but I have done 6-8 week runs with 50-75 mg of oral 3 ad and 150-200 mg 11-kt ( and 25 mg dhea for estrogen/joints) and done post pct bloods after 6 weeks of pct and been back at my baseline .

I’m sure I was a little suppressed on cycle , didn’t pull bloods on cycle though because I felt just as good or better than I would have off cycle . The important thing was I had good results which I wouldn’t have had if I had been extremely suppressed without supplementing some test back in AND I easily recovered to baseline
 
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Would this at be a better pick for someone who is cutting, over something like your AET50, Biostane, Arimihex? From my understanding they'd all do comparable things assuming the Kronos was dosed at 50-100mg? Just trying to figure out the best use case.

I think one benefit would obviously be the versatility of Kronos, as stated before it can be used low dose for cutting, higher dose for adding strength/mass.
 
Would this at be a better pick for someone who is cutting, over something like your AET50, Biostane, Arimihex? From my understanding they'd all do comparable things assuming the Kronos was dosed at 50-100mg? Just trying to figure out the best use case.

I think one benefit would obviously be the versatility of Kronos, as stated before it can be used low dose for cutting, higher dose for adding strength/mass.

IMO .... Yes.
 
Anyone have an idea on how much actually gets absorbed? If I were to begin TRT, I wouldn't go much higher than 250mg / week, so I'm trying to gauge the dosage here. Thanks!
 
Anyone have an idea on how much actually gets absorbed? If I were to begin TRT, I wouldn't go much higher than 250mg / week, so I'm trying to gauge the dosage here. Thanks!

Inj or TD for the test?

I keep my doses low these days and I like 1ml ED of Kronos.
 
So I'm planning to start this in a week or so when I begin a cut. I'm leaning towards 5 pumps/1 ml to start the day. I'll be using quite a few other topicals so it could be challenging to find enough space for all of them so I might need to be a little creative.

My question is whether this product requires any kind of cycle support products run alongside it or not.
 
So I'm planning to start this in a week or so when I begin a cut. I'm leaning towards 5 pumps/1 ml to start the day. I'll be using quite a few other topicals so it could be challenging to find enough space for all of them so I might need to be a little creative.

My question is whether this product requires any kind of cycle support products run alongside it or not.
No cycle support would be necessary.
:)
 
Good to hear. Is that still the case if I eventually bump up to 10 pumps/100 mg daily?

Yeah... No cycle support needed.

You'll hear different opinions on recovery supps (if that applies to you), but personally, I wouldn't even worry about it.

However.... If you're concerned at all ...
You could do a "mini PCT".

I usually tell people, if you're concerned about it .... Cover your concern. The cost is usually minimal.
 
Yeah... No cycle support needed.

You'll hear different opinions on recovery supps (if that applies to you), but personally, I wouldn't even worry about it.

However.... If you're concerned at all ...
You could do a "mini PCT".

I usually tell people, if you're concerned about it .... Cover your concern. The cost is usually minimal.
Do you expect that there is a sweet spot for dosing to largely avoid side effects? If this is effective at helping to shed fast a little faster/maintain muscle at 1 ml daily I'll just stick there, but if it's notably more effective at higher doses I'd likely consider working my way upwards.
 
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