Let’s Examine the Ingredients:
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Cordy-Plex – 1,500 mg.
Cordy-Plex™ is an exciting new ingredient designed to support cardiovascular and muscular endurance.
Cordy-Plex™ Highlights/Supports:
- Cardiovascular Endurance
- Muscular Endurance
- Delayed Fatigue
- Improved V02 Max
- Increased Oxygen Utilization
- Enhanced ATP Production
- Lactate Threshold Improvement
What is Cordy-Plex™?
Cordy-Plex™ is a revolutionary new ingredient designed to help support cardiovascular and muscular endurance in order to help you take your performance to the next level.
Cordy-Plex™ is a specialized combination of Cordyceps sinensis and Cordyceps militaris, two of the most powerful adaptogens known to man. These mushrooms have been used for centuries to help promote performance and vitality, and now, Cordy-Plex™ is bringing together specialized forms of them to help elite athletes and fitness enthusiasts push their limits like never before.
How does Cordy-Plex™ support improved endurance?
Cordyceps has several mechanisms through which it may help promote enhanced endurance:
- Increased Oxygen Utilization: Cordyceps has been shown in studies to have the ability to increase oxygen uptake and improve aerobic capacity. By supporting the body’s ability to utilize oxygen more efficiently during exercise, Cordyceps can support both cardiovascular endurance and overall aerobic performance.
- Enhanced ATP Production: Cordyceps has been shown in human studies to increase ATP production, which is crucial for energy during both muscular and cardiovascular exertion. ATP is the main energy currency of the body, and having more ATP available can help sustain prolonged physical activity, improving muscular endurance.
- Reduction in Fatigue: Cordyceps has been shown to reduce exercise-induced fatigue by improving mitochondrial function (the ‘powerhouses’ of cells). Increasing mitochondrial function can lead to more sustained energy during exercise and a reduced feeling of tiredness, which is essential to both muscular and cardiovascular function.
- Lactate Threshold Improvement: Cordyceps has been shown to help increase the lactate threshold, the point at which lactate builds up in the blood, causing fatigue. By delaying the onset of lactate accumulation, Cordyceps may help enable athletes and fitness enthusiasts to sustain intense efforts for longer periods without succumbing to fatigue as quickly.
- Adaptogenic Properties: Cordyceps has strong adaptogenic properties, meaning that it helps the body better handle both physical and mental stress. This is especially important for athletes who train hard and need to recover efficiently between workouts or events. The adaptogenic properties of Cordy-Plex™ help combat stress and improve overall resilience, allowing athletes to perform at their best without being overwhelmed by fatigue.
Cordy-Plex™ role in cardiovascular and muscular endurance:
Cordyceps has been shown to have a positive impact on both muscular endurance and cardiovascular endurance, although it is most particularly known for its cardiovascular endurance benefits, as it can enhance both aerobic capacity and improved V02 Max. However, it can also contribute to muscular endurance through improved cellular energy production and reduced fatigue, especially if the right types are used.
- Cardiovascular Endurance (Aerobic Performance): Cordyceps is particularly known for being beneficial for cardiovascular endurance, as it helps the body utilize oxygen more effectively during exercise. Improved V02 max translates into better performance in long-duration aerobic and cardiovascular intensive activities.
- Muscular Endurance: Cordyceps supports improved muscular endurance by boosting ATP production and improving overall energy metabolism, allowing muscles to perform for longer periods of time before fatigue sets in. This can be especially useful toward the end of long grueling workouts and in high-intensity, intermittent training such as HIIT or activities involving repeated short bursts of exertion.
- V02 Max: V02 max (maximal oxygen uptake) is a key determinant of cardiovascular fitness, and Cordyceps has been shown to increase V02 max in several studies, which would have a direct impact on aerobic endurance. A higher V02 max would allow you to perform higher intensities for longer periods, benefiting individuals who train for maximum endurance.
Cordy-Plex™ – A Deeper Understanding:
Above, we have explained how Cordy-Plex™ supports improved endurance and performance; this section will explain what Cordyceps is, the different types, the advantages of each – and through that, the significance of Cordy-Plex™ containing both Cordyceps militaris and Cordyceps sinensis.
What is Cordyceps?
Cordyceps is a mushroom that has been extensively studied for a variety of general health and performance benefits, and especially for its potential benefits on increasing endurance performance.
There is significant evidence supporting Cordyceps’ role in improving both muscular endurance and cardiovascular endurance, and studies also suggest that it can have a positive impact on V02 Max, which is a key indicator of cardiovascular fitness and performance.
Cordyceps Sinensis vs. Cordyceps Militaris
Cordyceps sinensis and Cordyceps militaris are two different species of the Cordyceps genus, and both are popular in traditional Chinese medicine (TCM) and modern supplementation for enhancing endurance and performance.
While both species share some similar general benefits, they do have key differences in their compositions, potencies, and specific benefits.
- Active Compounds:
- Cordyceps sinensis contains a variety of bioactive compounds, including cordycepin (a modified nucleoside) and polysaccharides, which are believed to have significant immune-modulating and endurance-boosting effects. The unique combination of these compounds is associated with energy enhancement, fatigue reduction, and improved stamina.
- Cordyceps militaris contains cordycepin (like C. sinensis), but it typically has higher concentrations of this compound, which is often credited for its ATP-boosting and anti-fatigue effects. Additionally, C. militaris tends to have a higher concentration of polysaccharides, which contribute to its immune-supporting benefits.
- Endurance Benefits:
- Both Cordyceps sinensis and Cordyceps militaris have shown positive effects on muscular endurance, cardiovascular endurance, and VO2 max due to their ability to increase ATP production, improve oxygen utilization, and reduce fatigue. However, their differences in active compounds may make each one better for specific goals, which is significant in that Cordy-Plex™ harnesses the power of both of them together.
- Cordyceps sinensis is generally regarded as more adaptogenic, meaning it can help the body better handle stress and improve overall vitality, which may be more beneficial for longer, steady-state endurance events where prolonged exertion is needed.
- Cordyceps militaris, with its higher concentration of cordycepin, may have a stronger effect on energy production and performance in high-intensity efforts, making it potentially more effective for shorter, intense bouts of exercise or events where maximal ATP output is needed.
Cordy-Plex™ provides you with the power of both Cordyceps sinensis and militaris in order to help you reach your health, fitness, athletic, and performance goals.
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Senactiv – 100 mg.
Senactiv® is the first senolytic sportsceutical that elevates exercise endurance, recovery, and energy while supporting senescent cell clearance and new muscle cell generation during high-intensity exercise.
Senescent cells, also known as “zombie cells”, are cells that have stopped dividing but remain alive. They accumulate in the body and can release harmful substances that can contribute to aging, age-related health problems, and have detrimental effects on muscle, strength, endurance, and performance.
Senactiv® Highlights/Supports:
- Exercise Endurance: Senactiv® helps your body clear out senescent cells, allowing for the generation of younger, more efficient muscle cells with higher energy production capacity. In a human clinical trial published in the esteemed PLOS One, Senactiv® was shown to increase endurance time (time to exhaustion) by 20% in a high-intensity (89% V02 max) cycling exercise.
- ATP Production: Senactiv® has been shown to increase ATP production by enhancing citrate synthase by up to 47%.
- Muscle Energy: Senactiv® promotes the generation of muscle cells with a higher number of mitochondria, the “powerhouses” of cells, resulting in increased energy production during exercise.
- Faster Recovery: Senactiv® supports improved recovery by activating the body’s cellular processes to clear out senescent cells (old, damaged cells) in muscles, allowing for the generation of new, healthy muscle cells which can perform better and recover faster.
- Muscle Cell Renewal/Regeneration: Senactiv® supports muscle cell renewal and regeneration by helping to eliminate senescent cells and promoting new muscle growth.
- Muscle Preservation: Senactiv® has been shown in human clinical studies to support muscle preservation by clearing senescent cells and reducing inflammation.
Muscle Tissue & Senescent Cell Clearance:
Muscle tissue is made up of a network of cells. These cells are constantly dividing and regenerating in order to maintain the health and function of the muscle tissue. However, at a certain point, these cells may stop regenerating and become senescent – which means that the cell is no longer a functioning part of the muscle tissue, but instead of ‘dying’ and being replaced by a healthy cell, it stays there taking up space where a healthy and contributing cell could be.
The higher the number of senescent cells in a tissue, the lower rate the tissue can perform.
Younger/newer muscle cells typically work harder and recover faster than older muscle cells because they have higher mitochondria counts, which may produce more energy and have greater ATP energy production capacity, leading to higher levels of cellular energy and endurance.
Senactiv® has been shown to help replace senescent cells with new muscle cells.
ATP & Citrate Synthase:
Senactiv® has been shown in human clinical studies to support ATP production by enhancing the activity of citrate synthase by up to 47%!
Boosting citrate synthase increases muscle energy by enhancing the rate of the Krebs cycle within the mitochondria, which is the primary pathway for generating ATP (cellular energy) from nutrients.
Essentially, increasing citrate synthase means more efficient energy production within the muscle cell.
Senactiv® is the first senolytic for enhanced exercise performance and endurance on the market.
Senactiv® helps to activate the body’s pathway to clear senescent cells, allowing for new muscle cell regeneration. Senactiv® supports the replacement of senescent cells with new muscle cells for improved endurance, enhanced exercise performance, and accelerated recovery.
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Salidroside (as SalidroPure™) – 25 mg.
Optimize Physical & Mental Performance with Salidroside!
Improved Endurance & Oxygen Utilization:
Salidroside is an adaptogen that helps the body cope with both physical and mental stress while supporting an increase in overall endurance and performance. This powerful compound helps increase the body’s resistance to fatigue, helping you to maintain higher levels of physical exertion for longer periods of time.
By helping to optimize oxygen utilization and reduce perceived exertion, Salidroside supports both mental and physical performance, making it an important ingredient for anyone looking to push through fatigue and perform at their best.
Mental Clarity, Cognitive Function, & Mood Support:
Salidroside supports enhanced mental clarity, mood, and cognitive function, helping you to stay sharp and focused throughout the day, whether you’re in the gym, training for sport, or managing a demanding schedule.
The SalidroPure™ Advantage:
Salidroside was originally only available in lower dosages because it had to be standardized from Rhodiola, and most normal Rhodiola only contained 1% Salidroside, meaning that a typical 300 mg. serving of Rhodiola would only give you 3 mg. Salidroside.
SalidroPure™ represents the evolution of Salidroside supplementation, especially for performance enhancement, by providing a much higher concentration that allows for much higher dosing and the ultimate in consistent potency so that you can feel and perform your best.
With SalidroPure™, you can now harness the power of highly dosed pure Salidroside to help take your endurance, focus, and overall performance to the next level.
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MitoBurn® (L-BAIBA) – 500 mg.
MitoBurn, frequently referred to as a natural exercise mimetic, is a revolutionary fat burning ingredient and is the first tested and verified form of L-BAIBA commercially available.
L-BAIBA, a metabolite of the amino acid L-Valine, is a powerful myokine (also known as ‘exercise factors’) and has the ability to stimulate certain ‘exercise factors’ that are released from skeletal muscle in response to muscular stress, especially muscle contraction.
L-BAIBA levels are associated with many of exercise’s numerous benefits, including amplifying the fat burning effects of exercise so you see results faster.
Up until now, the best way to increase L-BAIBA levels was through intense exercise, but now, MitoBurn allows you to support your body’s metabolic furnace!
MitoBurn Highlights/Supports:
- Stimulant free fat burning
- Natural metabolic enhancer
- Improved body-composition
- Helps mimic the effects of exercise
- Helps increase the benefits of exercise
- Amplifies the fat burning effects of exercise
- Supports the efficient use of fat for energy
- Healthy aging, mitochondrial, & cellular health
- Improved insulin sensitivity & carbohydrate tolerance
- Shown to initiate the “browning” of white adipose tissue
Research has shown that MitoBurn can help promote not only fat metabolism, but also energy metabolism and enhance exercise performance.
One study found that people who consumed MitoBurn showed better results during weight loss, losing weight faster while maintaining higher energy levels compared to a control group. This supports that MitoBurn not only helps with weight loss but also provides additional energy support and may help reduce fatigue and discomfort caused by dieting.
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CaloriBurn GP® – 150 mg.
Optimize Fat Loss with CaloriBurn GP®!
Aframomum Melegueta, also known as Grains of Paradise seed, is a spice native to West Africa that belongs to the same family as ginger. It has been shown in studies to support fat loss and improved body-composition in humans.
CaloriBurn GP® is a 100% Aframomum Melegueta (grains of paradise) extract, which is ethanol and water extracted through a natural proprietary technology with HPLC & HPTLC standards. This process preserves ALL of the metabolism-enhancing bioactive compounds from human studies: 6-Paradol, 6-Shogaol, and 6-Gingerol. It is an exciting ingredient that is ideal for those looking for improved body-composition and enhanced fat loss.
To understand how CaloriBurn GP® works, one needs to understand the difference between White Adipose Tissue (WAT) and Brown Adipose Tissue (BAT) in the body:
- White Adipose Tissue (WAT)/White Fat Cells – are your body’s energy storage cells; basically, they are the fat that your body stores as stored energy (leftover unburned calories from the food that you eat). Large amounts of white fat around the abdominal area are associated with a higher risk of metabolic disease.
- Brown Adipose Tissue (BAT)/Brown Fat Cells – are a very unique type of fat cell that is both thermogenic and metabolically active, burning calories rather than storing them like white adipose tissue. BAT is increasingly recognized as a powerful metabolic target, playing a significant role in body-composition and energy expenditure (calorie burning).
CaloriBurn GP® has the unique ability to help convert white fat to brown fat, thereby converting the energy storing fat tissue into the type of fat tissue that helps increase thermogenesis and total calorie expenditure.
Unlike many fat loss ingredients, Grains of Paradise/Aframomum is backed by human studies. One study showed that subjects had a significantly greater increase in energy expenditure, seemingly due to the increase in brown fat activity versus the placebo group.
Another study showed that subjects (non-obese women) that consumed Grains of Paradise/Aframomum had greater decreases in body-fat around the lower abdominals as well as lower levels of visceral fat in the same area as compared to those who consumed a placebo; and very significantly this was with both groups NOT making any changes in diet and exercise.
CaloriBurn GP® supports fat loss via the following mechanisms:
- Thermogenesis Activation: CaloriBurn GP® stimulates thermogenesis, a process where your body produces heat by burning fat. By increasing thermogenic activity, CaloriBurn GP® helps your body burn more calories, even at rest.
- Increased Fat Oxidation: Studies have shown that Grains of Paradise Extract helps increase the rate at which your body burns fat for energy, particularly from the abdominal area. This can result in a leaner physique and reduced visceral fat.
- Enhanced Metabolic Rate: By increasing metabolism, CaloriBurn GP® supports your body in efficiently utilizing and burning stored body fat.
CaloriBurn GP® is included in Cordarine for its potent fat burning and body-composition support benefits.
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Cocoabuterol® – 100 mg.
Fat Loss, Muscle Sparing, & Stimulant Free Energy Support!
Cocoabuterol® is a specialized natural cocoa (Theobroma cacao L.) extract that is custom engineered to contain the most bioactive compounds using the latest technologies. The major active ingredients in Cocoabuterol® are natural polyphenols and alkaloids, including N-Coumaroyldoamine, N-Caffeoyldopamine, and many more. All of these naturally occurring phytochemicals have a variety of incredible benefits throughout the body.
Cocoabuterol® Highlights/Supports:
- Thermogenic Effects: Cocoabuterol® supports fat loss through multiple pathways, a key one of which is its potent ability to help redirect the body from using muscle protein to instead start using stored fat and thereby making each workout more effective when trying to lose body-fat.
- Stimulant Free Energy & Mood Booster: Cocoabuterol® is unique in that it is stimulant free but is still associated with an increase in ‘feel good’ mental energy to help get you feeling more awake and mentally sharp. Also, being derived from chocolate, Cocoabuterol® supports an increase in positive mood to help you feel less stressed.
- Improved Insulin Sensitivity: Cocoabuterol supports improved insulin sensitivity and promotes a slight diuretic effect. This supports helping you better utilize your carbohydrates and to draw out excess water, leaving you with a leaner, harder, dryer, and more toned appearance.
- Lean Muscle Building & Sparing: Cocoabuterol® is so commonly associated with fat loss that many overlook its potential muscle building and muscle-sparing benefits. Cocoabuterol® supports muscle growth and muscle retention through supporting improved muscle protein synthesis, reduced muscle protein use, and improving adipose utilization.
This variety of fat burning, muscle sparing, and stimulant free energy and mood support benefits makes Cocoabuterol an excellent ingredient inclusion in Cordarine.
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GBB (as gbbBURN™) – 50 mg.
Thermogenic & Athletic Performance Support!
Gamma-butyrobetaine (GBB) is a precursor to L-Carnitine that has the ability to increase the body’s production of L-Carnitine and help improve energy levels, fat loss, athletic performance, and more.
GBB is referred to by some as ‘Super Carnitine’ and functions similarly to other L-Carnitine supplements but at a dramatically lower dosage and takes things a step further due to its ability to raise plasma levels of L-Carnitine.
GBB can also help support thermogenesis as evidenced by the increased sweating that some feel when using GBB which has led some people to say that they ‘feel the fat melting off’.
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AstraGin® – 25 mg.
AstraGin® is a natural patented ingredient complex comprised of highly fractionated Astragalus membranaceus and Panax notoginseng and created using pharmaceutical grade extraction and processing technology and designed to help enhance nutrient absorption
AstraGin® has been shown to help increase the bioavailability and absorption of a variety of key nutrients and may also support improved muscle recovery and growth following training as studies on ginsenosides (one of the key active constituents in AstraGin®) note that it activates the mTOR signal pathway by regulating upstream kinases in muscle cells.
AstraGin® is a perfect ingredient in the super comprehensive Cordarine formula to help make sure that you properly absorb the other great nutrients in Cordarine for maximum results and also for its potential mTOR signaling benefits.
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Bioperine® – 10 mg.
Bioperine® is a standardized extract from the fruit of Piper nigrum L (Black Pepper) containing 95% piperine. Piperine has been shown to enhance the oral bioavailability of many ingredients.
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