Sensitive nipples since increasing mk677 dose??

CroLifter

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So here it is, experiencing sensitivity in my left nipple for the first time ever, started roughly 5 days into increasing mk677 from 12.5 to 20mg per day.

I previously ran 500 test with no ai, had estrogen over 100 pg/ml, never experienced any nipple sensitivity.

Other than mk i am 100mg test per week plus hcg as usual and i dont need ai at that dose.
Occasionally i woul take half aromasin if i started feeling emotional but that is about it.

Other than that, mk677 has sent my libido down the drain, so maybe the two (nipple sensitivity and low libido) are connected...who knows.

And i know it is legit mk677. It is in liquid form and hunger is here, initial bloat that went away after about a week was there, lethargy is here and improved quality of sleep...everything points in the direction that this is 100% legit mk677.


But i was just interested to hear from you guys...has anyone experienced any nipple sensitivity from mk677 / secretagogues? I know they have no effect on estro and steroid hormones...but perhaps prolactin is at play, which i am sensitive to anyway?
I had issues with high prolactin on test only.

Maybe my estro is ever so slightly elevated and mixed with higher prolactin causes these issues?
 
ValiantThor08

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MK677 can raise prolactin. That will reduce libido and increase nipple sensitivity. You can take something as simple as Prolactrone, no need for prami or any of the likes. An OTC prolactin reducer will be sufficient.
 

redtrek

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I'll take it for a few to several days, then take 1 or more days off. Definitely notice on my off days that libido goes up, so that could point to prolactin, but haven't had sensitivity yet... I do stick to 12.5mg bc 25mg was a bit too annoying for me. So it at least makes sense you might be seeing more adverse effects with the increased dose.
 
Alchemist11

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So here it is, experiencing sensitivity in my left nipple for the first time ever, started roughly 5 days into increasing mk677 from 12.5 to 20mg per day.

I previously ran 500 test with no ai, had estrogen over 100 pg/ml, never experienced any nipple sensitivity.

Other than mk i am 100mg test per week plus hcg as usual and i dont need ai at that dose.
Occasionally i woul take half aromasin if i started feeling emotional but that is about it.

Other than that, mk677 has sent my libido down the drain, so maybe the two (nipple sensitivity and low libido) are connected...who knows.

And i know it is legit mk677. It is in liquid form and hunger is here, initial bloat that went away after about a week was there, lethargy is here and improved quality of sleep...everything points in the direction that this is 100% legit mk677.


But i was just interested to hear from you guys...has anyone experienced any nipple sensitivity from mk677 / secretagogues? I know they have no effect on estro and steroid hormones...but perhaps prolactin is at play, which i am sensitive to anyway?
I had issues with high prolactin on test only.

Maybe my estro is ever so slightly elevated and mixed with higher prolactin causes these issues?
Is there any compound man, that you took and didn't have side effects?
 

CroLifter

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Can we please stick to the topic and leave the bullsh1t out of here?

Of course drugs are going to have side effects. If they dont, then they are ineffective.

I have caber but wont introduce it yet, maybe i need just a little bit more aromasin. Will see how things develop before introducing/increasing drugs,

And yes, i will be lowering to 12.5mg oer day once i start training again because the lethargy at 20mg is a little bit too high for me...gets tough when you have to functio the whole day.

And this is the only compound that gave me sensitive nips, for the record.

@redtrek you say it was annoying at 25mg...any other issues other than low libido?

It killed my libido (am single, so not an issue) but it is the lethargy that annoys me. So as i said, once i recover from illness and start training, will lower to 12.5mg. Felt i was gonna collapse today at the store.
 
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Renew1

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Can we please stick to the topic and leave the bullsh1t out of here?

Of course drugs are going to have side effects. If they dont, then they are ineffective.

I have caber but wont introduce it yet, maybe i need just a little bit more aromasin. Will see how things develop before introducing/increasing drugs,

And yes, i will be lowering to 12.5mg oer day once i start training again because the lethargy at 20mg is a little bit too high for me...gets tough when you have to functio the whole day.

And this is the only compound that gave me sensitive nips, for the record.

@redtrek you say it was annoying at 25mg...any other issues other than low libido?

It killed my libido (am single, so not an issue) but it is the lethargy that annoys me. So as i said, once i recover from illness and start training, will lower to 12.5mg. Felt i was gonna collapse today at the store.
This is why I almost never reply to your threads any more. You've made it clear that you don't want people's honest opinion on what you post. You have a certain type of response that you deem acceptable beforehand, and anything else you deem bullsh*t.

The truth is that what @Alchemist11 said is true. And if someone seems to have a common issue running through all of their cycles, that is probably more of an issue than the particulars in each.
He wasn't pointing it out to needle you, he pointed it out so that you could hopefully try to figure out why this seems to be the case ... And how you might be able to correct it. For your own benefit.
 

CroLifter

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This is why I almost never reply to your threads any more. You've made it clear that you don't want people's honest opinion on what you post. You have a certain type of response that you deem acceptable beforehand, and anything else you deem bullsh*t.

The truth is that what @Alchemist11 said is true. And if someone seems to have a common issue running through all of their cycles, that is probably more of an issue than the particulars in each.
He wasn't pointing it out to needle you, he pointed it out so that you could hopefully try to figure out why this seems to be the case ... And how you might be able to correct it. For your own benefit.
Yeah because compounds cannot cause sensitive nips...I simply wanted to hear experiences from others.

And yes please do not reply to my threads if you think it is redundant. I wont lose sleep over it.
 
Renew1

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Yeah because compounds cannot cause sensitive nips...I simply wanted to hear experiences from others.

And yes please do not reply to my threads if you think it is redundant. I wont lose my sleep over it.
That's not what I said at all. But if that's what you want ... You got it.
 

CroLifter

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The reason i am holding off from using anti-prolactin drugs is my reasoning that if gh secretagogues stimulate prolactin release then inverse might be true...ie inhibiting prolactin release might hinder or lessen gh release as they are secreted at almost the same place in the pituitary...hence the reason why secretagogues increase prolactin in the first place...gh release "pulls" some prolactin alongside.

Total broscience though.
 

redtrek

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any other issues other than low libido
not exactly lethargy, but dream-like feelings that would in turn make me slower. definitely more hunger, and seemingly worse digestion. wouldn't be surprised if blood pressure were higher since heart beat was more noticeable in bed but didn't actually measure it, so couldve been mental sides since it clearly has some effects on perception for me.
 
ValiantThor08

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I actually was under impression that gyno couldnt form under influence of prolactin by itself, without elevated estrogen.

maybe i was wrong.
Overall you do not want increased prolactin if you are not a lactating woman. B6 or p5p. Or ldopa. Dont combine b6 and ldopa.
 

CroLifter

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not exactly lethargy, but dream-like feelings that would in turn make me slower. definitely more hunger, and seemingly worse digestion. wouldn't be surprised if blood pressure were higher since heart beat was more noticeable in bed but didn't actually measure it, so couldve been mental sides since it clearly has some effects on perception for me.
It does seem to spike anxiety in some, ghrelin is a stress hormone. I felt it a bit but since i know where it is coming from it is not bothering me.

And yes! Dream like feelings exactly. Feeling like i am half-asleep, basically feeling like my senses are diminished.
 
Jinsun

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Guys, stop busting his balls. Prolactin sides are a genuine issue with mk677. I had them to and got gyno from it.

CroLifter, if you have caber please use it asap. Dont mess around with gyno, it's there for ever.
 

CroLifter

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Guys, stop busting his balls. Prolactin sides are a genuine issue with mk677. I had them to and got gyno from it.

CroLifter, if you have caber please use it asap. Dont mess around with gyno, it's there for ever.
Damn man you scaring me 😀

I dont like caber because of hallucinations but i guess i will have to take it.

But i think, for me personally, 12.5mg is where it is at for mk677. At 20mg lethargy is too harsh.

But other than that i like it. Amazing sleep. Hard to fall asleep but once i do i do not wake up till morning.

Also, after initial bloating went away, i am dry and vascular af. Actually flat as if i am dieting and i am eating like a hog.

it definitely increased my basal metabolic rate.
 
Alchemist11

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We're just trying to say that if you constantly have to reduce side effects from certan compounds, which are already serious medications, with more serious medications, whats the point and joy of taking stuff?
Some big % of its due to his head, yes, but if you are going to take Caber for half of a standard Mk dosage, you loose the point of running it in the first place.
 

CroLifter

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We're just trying to say that if you constantly have to reduce side effects from certan compounds, which are already serious medications, with more serious medications, whats the point and joy of taking stuff?
Some big % of its due to his head, yes, but if you are going to take Caber for half of a standard Mk dosage, you loose the point of running it in the first place.
I agree taking more drugs isnt the answer,

I dont want to take caber if i dont have to i hate it.
And i dont have to if i lower the dose lol go figure.

Btw 20mg seems just about right as far as dose goes, it is not half the dose (20/25 = 80%) but yeah i personally like it at 12.5mg more because i have no sides at that dose.

So i will lower to 12.5 soon rather than introduce caber.

edit: It is also my belief that taking anti prolactin will lower effectiveness of secretagogue. Broscience but refer to my previous post for my reasoning.
 

CroLifter

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So now i know how all this nipple sensitivity starts. At first i only felt soreness, but it wasnt sore to the touch. Then i just woke up one day and it was sore to the touch.

Thought it was some phantom soreness at first.

Unfortunately 2 knots already formed. That can only happen to me, to run 500 test without ai no issues and then get gyno on 100 test and some mk.

i am pissed.
 
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boooosted

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Since you don't seem to really mind the low libido, and the gyno is really the only thing you're worried about with prolactin being high, why not try some ralox instead of caber. I don't think I've seen anyone have a side effect from ralox and certainly not hallucinations.
 

CroLifter

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Since you don't seem to really mind the low libido, and the gyno is really the only thing you're worried about with prolactin being high, why not try some ralox instead of caber. I don't think I've seen anyone have a side effect from ralox and certainly not hallucinations.
Yeah i will see what i can source in the pharmacy. Probably only nolva but it should suffice.

It is not that sensitivity is bothering me, but of course that i am worried that it will flare up, which is always a possibility.

Although i dont like running serms. But maybe it is the price to pay if i wanna run mk677.

But seriously, as @Alchemist11 stated, taking a very harsh drug like caber just to combat sides from mk677 is not a good long term plan.
 

redtrek

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Unfortunately 2 knots already formed. That can only happen to me, to run 500 test without ai no issues and then get gyno on 100 test and some mk.
What's your bf% like? It might not be as bad as you think since the pseudo-gyno stuff will shrink quite a bit on a cut
 
Jinsun

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What are you talking about? Caber being a very harsh drug? It's not a harsh drug. Take it for crying out loud. You've got two lumps already. Jeez, what more do you want? Even if you stop using mk right away, prolactin wont drop over night. Your gyno is still going to continue solidifying if not frowing a bit more. 12.5mg will also still be raising prolactin and it wont affect your gyno in a good way.

And btw, having sensitive nipples IS a gyno flare up.

Use caber and nolva both at once. No matter what you do with mk. And continue using nolva for 2 months or so, so it can reduce the lumps.
 

CroLifter

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Well i was reading about gyno surgery and the result was me taking caber this morning lol as i couldnt source raloxifene and sensitivity was worsening despite increasing aromasin. Wont take mk for few days, might be a good idea anyway to give pituitary some rest, as mk gives continouous pulses unlike ghrp's.

Fun fact. Taking caber with grapefruit juice will roughly double its strength. Took 0.25mg and drank grapefruit juice , feeling rather weird hahahahha nipple sensitivity went down a bit.
But since it is an expensive drug it may make your stash last longer as you can take lower doses and still get desired effects.

but i get this druggy feel from it. Like after some time you nptice you are acting and perceiving things different.
 
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Jinsun

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Well i was reading about gyno surgery and the result was me taking caber this morning lol as i couldnt source raloxifene and sensitivity was worsening despite increasing aromasin. Wont take mk for few days, might be a good idea anyway to give pituitary some rest, as mk gives continouous pulses unlike ghrp's.

Fun fact. Taking caber with grapefruit juice will roughly double its strength. Took 0.25mg and drank grapefruit juice , feeling rather weird hahahahha nipple sensitivity went down a bit.
But since it is an expensive drug it may make your stash last longer as you can take lower doses and still get desired effects.

but i get this druggy feel from it. Like after some time you nptice you are acting and perceiving things different.
Good choice. Glad you listened.

Yeah, I might have experienced something similar with it. But it is mostly the low blood pressure, that I have an issue with. My legs felt heavy, every time I stood up I got ringing and pressure in my head and seeing black... Be careful, this can be dangerous while driving and not to mention, that you can faint, fall and hurt your head.
 

CroLifter

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Good choice. Glad you listened.

Yeah, I might have experienced something similar with it. But it is mostly the low blood pressure, that I have an issue with. My legs felt heavy, every time I stood up I got ringing and pressure in my head and seeing black... Be careful, this can be dangerous while driving and not to mention, that you can faint, fall and hurt your head.
Yes caber drops my bp to 100-105/60.
It is called orthostatic hypotension ( low bp in standing position) when you get up and feel shortness of breath and malaise.

i once took it with cialis, bp dropped to 95/55, couldnt stand on my feet at all.

I am still sceptical of prolactin only induced gyno and i believe my estro might be slightly elevated which in combination with elevated prolactin causes issues.


But i am pissed that i have issues with mk677 when most have no sides and can enjoy it. It must be the Wrath Of God 😈 descending upon me as i have finally discovered a substwnce which can give me slight gains over natty and help me keep mass while sick without wrecking my bloodwork...
 
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Jstrong20

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The reason i am holding off from using anti-prolactin drugs is my reasoning that if gh secretagogues stimulate prolactin release then inverse might be true...ie inhibiting prolactin release might hinder or lessen gh release as they are secreted at almost the same place in the pituitary...hence the reason why secretagogues increase prolactin in the first place...gh release "pulls" some prolactin alongside.

Total broscience though.
Not true because prami reduces prolactin and raises gh.
 

Jstrong20

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The reason i am holding off from using anti-prolactin drugs is my reasoning that if gh secretagogues stimulate prolactin release then inverse might be true...ie inhibiting prolactin release might hinder or lessen gh release as they are secreted at almost the same place in the pituitary...hence the reason why secretagogues increase prolactin in the first place...gh release "pulls" some prolactin alongside.

Total broscience though.
Not true because prami reduces prolactin and raises gh.
 

CroLifter

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Not true because prami reduces prolactin and raises gh.

Also, anti estrogenic drugs like ai's and serms decrease igf 1.

Another reason to avoid ai's, serms and dopamine agonists as much as possible, not only are they toxic but they are detrimental to growth.

and that is why if you are serious about this best to get glands removed...no messing with all these damn drugs anymore.

As @Alchemist11 said, taking a drug that warrants the need to take 2 more drugs is stupid.
 
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CroLifter

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Resuming mk after a 2 day break today. Nipple sensitivity is way down.

however if it flares up again i wont be using mk anymore. I cant be taking caber constantly.

Since secretagogues seemingly universally increase prolactin, maybe hgh will be the only thing i am able to use.
 

redtrek

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Resuming mk after a 2 day break today. Nipple sensitivity is way down.

however if it flares up again i wont be using mk anymore. I cant be taking caber constantly.

Since secretagogues seemingly universally increase prolactin, maybe hgh will be the only thing i am able to use.
Hopefully won't be an issue at lower dose. Also definitely recommend at b-vitamin complex, since b-6 was a good suggestion, and all the b-vitamins help with various things in their own ways. The one I happen to take EOD at the moment has 100mg pyridoxine - 5882 %DV!
 

CroLifter

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I find hgh much easier on the nips than mk. My current protocol:

2 iu hgh: 6 am
200 mcg GHRP-2: preworkout
10 mg mk-677: 6 pm

I have no sides other than mild lethargy and increased appetite with this protocol. Also bloat only occurs if I overdo carbs. 25 mg mk-677 and I always run into nip issues.
This looks good. However i would only go with gh and mk, to keep things less complicated and lessen the number of pins (if i am going to do this protocol).

But the fat loss with mk677 at 20-25mg per day is legit. But i guess 2iu gh + 10mg mk must be even better.

I find the gh pathway to be what was missing to my cycle. I could have been so much leaner had i incorporated some gh or secretagogues.

This might be a good idea to incorporate into the 2nd part of my next cycle where i will run test e with a low dose of tren ace. I had some guys locally here say that gh lessens the sides of tren. I dont understand how it can do that but hey if the guys who have done it say so...there must be some truth to that.
 
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Dcoopair

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Overall you do not want increased prolactin if you are not a lactating woman. B6 or p5p. Or ldopa. Dont combine b6 and ldopa.
Why no combo of the two..couldn't find any thing with simple Google search..some products have all 3
 

Dcoopair

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Interesting..something to think about..I don't want to elevate my prolactin just like everyone else
 

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****. I just bought some Mk-677 and am hesitant as **** about possible prolactin issues.
I have a decent supply of B6 (Pyroxidine) tabs 100mg and 250mg on hand. Would these suffice for preventative prolactin control, or are they a joke compared to cabergoline & pramipexole?
 

CroLifter

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Like i said, if you control your estrogen you wont have any prolactin issues. I am off aas now (been off for over 5 months now) and running 20mg mk677 a day.

0 nipple sensitivity.

Btw another positive side effect of mk677 are pumps. I was doing hammering on some steel today. Talk about forearm pumps!
 

Jstrong20

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The reason i am holding off from using anti-prolactin drugs is my reasoning that if gh secretagogues stimulate prolactin release then inverse might be true...ie inhibiting prolactin release might hinder or lessen gh release as they are secreted at almost the same place in the pituitary...hence the reason why secretagogues increase prolactin in the first place...gh release "pulls" some prolactin alongside.

Total broscience though.
No worries they do not. Prami actually raises gh. If anything it would make the mk677 more effective. Not sure on caber but pretty sure l dopa also raises gh to some degree. Also If your worried about sides you may want to avoid prami. I like it but many hate it.
 

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