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Dht in muscle cells?

Toe_cutter

New member
So I've been researching and from what I've read dht is way stronger than testosterone in everything but muscle cells. And that muscle cells have an enzyme 3a hydroxy that rapidly converts dht to something less than useful. Then I see in another paper that the nsaid indomethacin blocks this enzyme. And has shown to increase reparatory anabolism. Any thoughts?
 
So I've been researching and from what I've read dht is way stronger than testosterone in everything but muscle cells. And that muscle cells have an enzyme 3a hydroxy that rapidly converts dht to something less than useful. Then I see in another paper that the nsaid indomethacin blocks this enzyme. And has shown to increase reparatory anabolism. Any thoughts?

I'm really not sure what you're referring to.

In general, DHT makes you stronger. In theory, and in practice.
 
Sorry. Didn't coordinate my thought process, long day. From my understanding dht is stronger than testosterone. But has a less anabolic effect in muscle cells because muscle cells have enzyme that converts it fairly quickly into a much weaker androgen. It would still provide some benefits but they are reduced by the 3a hydroxy enzyme. Indomethacin inhibits that enzyme, which would make dht more anabolic longer right since more stays active, and has been shown in studies to increase reparatory anabolism by over 50%. With others suggesting decrease in prostate issues and reduced coronary artery inflammation, which both sound kinda good.

I was basically getting at if anyone thought this might have potential applications. Kinda like how they say proviron don't do jack alone but makes a cycle better.
 
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Sorry. Didn't coordinate my thought orocess, long day. From my understanding dht is stronger than testosterone. But has a less anabolic effect in muscle cells because muscle cells have en enzyme that converts it fairly quickly into a much weaker androgen. It would still provide some benefits but they are reduced by the 3a hydroxy enzyme. Indomethacin inhibits that enzyme, which would make dht more anabolic longer right since more atays active, and has been shown in studies to increase reparatory anabolism by over 50%. With others suggesting decrease in prostate issues and reduced coronary artery inflammation, which both sound kinda good.

I was basically getting at if anyone thought this might have potential applications. Kinda like how they say proviron don't do jack alone but makes a cycle better.

Hmmm. Sounds interesting. I'll take a look. Thanks.
 
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