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Cardarine....is there any where to get legit cardarine ?

Complicated man. Yesss the rats rapidly developed cancer with high dosages running for an extended amount of time, and when you factor in the metabolic rates, the dosage is not especially high in people. But the role of PPAR agonism in rats is different from that in humans. It may not be cancerous. Either way, I won't touch it
 
Cgkone said:
Wait a minute are you telling me rats and humans are different?
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Yes, but before anyone brings up the cell studies (in vitro), isolated cells and a human organism are also vastly different. We simply don't know with any level of certainty either way (neither rodent studies nor in vitro studies can tell us with certainty, especially when they have conflicting results), but people typically decide to "err on the side of caution" on this sort of thing. We all have to decide risk vs reward for ourselves though.
 
muscleupcrohn said:
Yes, but before anyone brings up the cell studies (in vitro), isolated cells and a human organism are also vastly different. We simply don't know with any level of certainty either way (neither rodent studies nor in vitro studies can tell us with certainty, especially when they have conflicting results), but people typically decide to "err on the side of caution" on this sort of thing. We all have to decide risk vs reward for ourselves though.
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Yes the HED seems like a problem, but until how PPARs act in humans is fully understood we won't know. Maybe cardarine elevates the potential of cancer by 1000%, which manifests itself 20 years from now... As a warning to people
 
SARMS said:
Yes the HED seems like a problem, but until how PPARs act in humans is fully understood we won't know. Maybe cardarine elevates the potential of cancer by 1000%, which manifests itself 20 years from now... As a warning to people
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Once HED is factored in, some of the studies were actually pretty moderately dosed, and definitely nowhere near a factor of safety of 10 that's recommended to start human trials based on FDA guidelines. I'd stay away from it personally.
 
muscleupcrohn said:
Once HED is factored in, some of the studies were actually pretty moderately dosed, and definitely nowhere near a factor of safety of 10 that's recommended to start human trials based on FDA guidelines. I'd stay away from it personally.
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Yes me too. Especially since there alternatives. But the idea is very cool, superhuman endurance... I wonder what Cardarine's future will be
 
SARMS said:
Yes me too. Especially since there alternatives. But the idea is very cool, superhuman endurance... I wonder what Cardarine's future will be
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GSK and Ligand have abandoned development on it, and are currently working on a replacement that they hope will have similar effects (benefits) with a more favorable (less risky/questionable) safety profile. That's what I've read anyway.
 
muscleupcrohn said:
Yes, but before anyone brings up the cell studies (in vitro), isolated cells and a human organism are also vastly different. We simply don't know with any level of certainty either way (neither rodent studies nor in vitro studies can tell us with certainty, especially when they have conflicting results), but people typically decide to "err on the side of caution" on this sort of thing. We all have to decide risk vs reward for ourselves though.
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GW-072? Its out. Not sure what it is yet though.
 
muscleupcrohn said:
Yes, but before anyone brings up the cell studies (in vitro), isolated cells and a human organism are also vastly different. We simply don't know with any level of certainty either way (neither rodent studies nor in vitro studies can tell us with certainty, especially when they have conflicting results), but people typically decide to "err on the side of caution" on this sort of thing. We all have to decide risk vs reward for ourselves though.
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I was trying to be funny.
No but seriously, you made me pause on GW use. Scared me.
 
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