Clarification on Anacyclus

[Rockzilla]

Maybe someone can help me out in trying to figure out AC dosing.
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That’s the study. It used at minimum 50mg/kg of Anacyclus extract.
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I am not understanding the conversion that examine did.
They say for a 150 lb individual 550-1600mg of root extract. But a 150 person is 68 Kgs, that would mean the amount of extract they should be looking for is 3400 - 10200mgs of root extract. PR XT has 3200 mgs of Anacyclus at a 5:1 extract. A 5:1 of 3200 is 3200:640. That means 640 mgs of actual root extract. Which by examines conversion(which I don’t understand) is the lower end of the spectrum which would be for someone around my size.

Am I reading right or?

 

[muscleupcrohn]

Maybe someone can help me out in trying to figure out AC dosing.
Invalid Link Removed
That’s the study. It used at minimum 50mg/kg of Anacyclus extract.
Invalid Link Removed
I am not understanding the conversion that examine did.
They say for a 150 lb individual 550-1600mg of root extract. But a 150 person is 68 Kgs, that would mean the amount of extract they should be looking for is 3400 - 10200mgs of root extract. PR XT has 3200 mgs of Anacyclus at a 5:1 extract. A 5:1 of 3200 is 3200:640. That means 640 mgs of actual root extract. Which by examines conversion(which I don’t understand) is the lower end of the spectrum which would be for someone around my size.

Am I reading right or?

The link doesn't seem to be working. Was that 50mg/kg in rats? If so, you have to multiply it by 0.16 (HED conversion), which gives you 8mg/kg for humans. Multiply that for an 80kg human gives you 640mg. I see one rat study on anacyclus used 50 and 100 mg/kg, so that'd be 640-1280mg for an 80kg human. As for the ratio/potency of the extract used, the study states that the yield of the extract was 3.1%. So if you take the 640mg, with a 3.1% yield, that should give you a total dose (not an extract) of about 20g. 3200mg of a 5:1 extract would be 16g, so pretty close really, especially if you're less than 80kg.

 

[muscleupcrohn]

This study?
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[Rockzilla]

This study?
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Yeah that’s it. My link had one that had a control, 50mg, 100mg, and 150mg/kg for the rats.

Well not exactly the same study, the link that doesn’t work used aqueous extract. But it’s pretty much the same thing except for the measurements used.

 

[Rockzilla]

The link doesn't seem to be working. Was that 50mg/kg in rats? If so, you have to multiply it by 0.16 (HED conversion), which gives you 8mg/kg for humans. Multiply that for an 80kg human gives you 640mg. I see one rat study on anacyclus used 50 and 100 mg/kg, so that'd be 640-1280mg for an 80kg human. As for the ratio/potency of the extract used, the study states that the yield of the extract was 3.1%. So if you take the 640mg, with a 3.1% yield, that should give you a total dose (not an extract) of about 20g. 3200mg of a 5:1 extract would be 16g, so pretty close really, especially if you're less than 80kg.

So a PR XT serving is giving you 16g of Anacyclus total, while giving you 3200mg of extract?

 

[muscleupcrohn]

So a PR XT serving is giving you 16g of Anacyclus total, while giving you 3200mg of extract?

In simplest terms, 3200mg of that extract is equivalent to around 16g of the raw herb. 5:1 extract means it’s 5x as potent or concentrated as the source material, so you only need 1/5 the dose of what you’d need from the source material. I hope that makes sense.

 

[Rockzilla]

In simplest terms, 3200mg of that extract is equivalent to around 16g of the raw herb. 5:1 extract means it’s 5x as potent or concentrated as the source material, so you only need 1/5 the dose of what you’d need from the source material. I hope that makes sense.

Ok, I understand now