I absolutely respect the non-stim direction. Nobody wants to feel jittery or on edge, so that is a very personal choice. Assass1nate has a decent profile and looks to serve well to suppress one's appetite. I think taking it with fish oil / or krill oil would make it even better.
Also, I wanted to add, resetting one's leptin sensitivity with food is important because unlike those rats being tested, humans can have large quantities of leptin even in the obese. It's the sensitivity that is lacking, and it works in conjunction with insulin. A nice refeed occasionally would go a long way towards this.