Supplements to Increase GLUT-4 Receptors?

As mentioned above, Berberine HCL, Banaba (Corosolic Acid), and Na-Rala. Also Agmatine, Salacia Reticulata/Oblonga, Fenugreek Seed Extract (4-Hydroxyisoleucine), Cinnamon (Cinnamaldehyde), Gymnema Sylvestre (Gymnemic Acid), and Bitter Melon are good too. Pretty much most of the common GDA ingredients should do the trick.
 
Z28Luver7777 said:
Where would you find 15mg of corsolic acid
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Banaba Leaf extracts standardized for 1%, 1.5%, and 2% are common and easy to find. Depending on the standardization just adjust to dosage accordingly. For example:

Banaba 1% - 1500mg x .01 = 15mg CA
Banaba 1.5% - 1000mg x 0.015 = 15mg CA
Banaba 2% - 750mg x .02 = 15mg CA

and if you are fortunate enough to find the following:

Banaba 10% - 150mg x .10 = 15mg CA
Banaba 20% - 75mg x .20 = 15mg CA
 
Do you mean to increase the function /sensitivity of , or the actual physical numbers? Those supps mentioned will likely not change the physical numbers of GLUT 4 receptors
 
hsk said:
Banaba Leaf extracts standardized for 1%, 1.5%, and 2% are common and easy to find. Depending on the standardization just adjust to dosage accordingly. For example:

Banaba 1% - 1500mg x .01 = 15mg CA
Banaba 1.5% - 1000mg x 0.015 = 15mg CA
Banaba 2% - 750mg x .02 = 15mg CA

and if you are fortunate enough to find the following:

Banaba 10% - 150mg x .10 = 15mg CA
Banaba 20% - 75mg x .20 = 15mg CA
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Would dosing 1g of bulk agmatine sulfate powder two or three times per day be just as effective?
 
InItForGainz said:
Would dosing 1g of bulk agmatine sulfate powder two or three times per day be just as effective?
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As effective, probably not as effective as some of the other options listed in here. But it is great to use for GDA purposes as it improves glucose uptake and insulin sensitivity of skeletal muscles.and glucose uptake in skeletal muscle tissue
 
AntM1564 said:
As effective, probably not as effective as some of the other options listed in here. But it is great to use for GDA purposes as it improves glucose uptake and insulin sensitivity of skeletal muscles.and glucose uptake in skeletal muscle tissue
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I can find bulk Agmatine Sulfate but not any banaba extracts.
Do you know if Agmatine Sulfate has a build up effect or is it just dose dependant?
 
InItForGainz said:
Would dosing 1g of bulk agmatine sulfate powder two or three times per day be just as effective?
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It will help but as AntM1564 said, some of the other supplements listed above will be more effective/potent at lower dose.

InItForGainz said:
I can find bulk Agmatine Sulfate but not any banaba extracts.
Do you know if Agmatine Sulfate has a build up effect or is it just dose dependant?
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Swanson's High Potency Banaba Extract 2% Corosolic Acid (60mg x 90 caps)
Paradise Herbs Banaba Leaf 1.5% Corosolic Acid Vegetarian Capsules (250mg x 60 or 180 caps)
If you want bulk powder you can try Amazon, Ebay, or search engine.

It is possible to build a tolerance for any supplement. Most people use 1g-3g daily. I use 2g-2.5g daily for pain management, and any pump or GDA benefit is secondary for me as there are better options.

InItForGainz said:
Thoughts on stacking agmatine sulfate with Swanson's Premium Berberine Complex for nutrient partitioning?
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You can probably combine 500mg-1000mg of Agmatine Sulfate with the product you mentioned for each meal. You can also make your own DIY GDA with some common ingredients that can all be found at the retailer you mentioned.

Swanson's Berberine (400 mg x 60 Caps)
Swanson's High Potency Banaba Extract 2% Corosolic Acid (60mg x 90 caps)
Swanson's Gymnema Sylvestre 75% Gymnemic Acid (300mg x 90 caps)

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The thread above should give you an idea how to combine 3 of the most common GDAs and then just add however much Agamtine you would like accordingly. You other option is to look at some of the GDA formulas with open labels and see how they dose the product you want to use and then you can use that as a guide. You should also try each of the ingredients individually to see how you respond and then decide if you want to add it into a formula.
 
ma70 said:
Just use the ingredients in bulk. That complex is underdosed for certain compounds
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Can't find any bulk Berberine or banaba extract over here in the UK. I spent a decent amount of time looking last night and haven't been able to find anything decent
 
Thoughts on 18% corsolic acid?

I'm seeing a few supplements with that extract in it, but other sites stating 2% is one of the highest?
 
Z28Luver7777 said:
Thoughts on 18% corsolic acid?

I'm seeing a few supplements with that extract in it, but other sites stating 2% is one of the highest?
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The ones with 18% (glucofit/glucohelp) are overpriced and under dosed. You would need to take an obscene amount of those gel caps to get a reasonable amount of total Corosolic Acid which would make it uneconomical. As far as single ingredient bulk capsules are concerned, 1.0%, 1.5% and 2.0% Corosolic Acid are the highest that can be found easily.

Discontinued Products that were known to have high % Corosolic Acid extracts:

USP Labs Pslin - Prop Blend formula with min 10% Corosolic Acid
EBF/LBF Recompadrol - Prop blend formula with min 20% Corosolic Acid
USP Powders - Pslin bulk powder (min 10% Corosolic Acid)
Nutraplanet - 20% Corosolic Acid bulk powder

I am sure many members here will agree with me when I say that these discontinued products have been missed greatly, especially Recompadrol.
 
InItForGainz said:
Can't find any bulk Berberine or banaba extract over here in the UK. I spent a decent amount of time looking last night and haven't been able to find anything decent
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Check nutraplanet, I remember them selling it. Never buy a berberine powder, lol. It stains yellow like crazy
 
InItForGainz said:
Can't find any bulk Berberine or banaba extract over here in the UK. I spent a decent amount of time looking last night and haven't been able to find anything decent
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You can also add Vanadyl Sulfate (Vanadium) and GTF Chromium (Chromium Polynicotinate). These should be easy to find and are both and affordable.
 
Z28Luver7777 said:
What do these do?
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They are both minerals and have been studied for their effects in diabetics and insulin resistance. Vanadium can lower blood glucose and block gluconeogenesis. Chromium can help the body use insulin more efficiently. They have been around a long time and can be found individually and in formulas.
 
Let me know if I'm wrong but I this is how I see it,
We eat food-
Food gets broken down into nutrients-
Nutrients are taken into the blood stream-
Glut 4 takes the nutrients from the blood stream and puts them into muscle tissue-
Muscle tissue size increases.

This leads me to two questions,

1)Does this mean that Glut 4 sensitivity has a direct effect on increasing muscle size?
2)How much can we realistically increase muscle size with these insulin sensitizers/mimetics?
 
any thoughts on acute caffeine usage potentially reducing Glut4 expression?

study for reference: Acute vs chronic caffeine: Are the effects on insulin sensitivity mediated by altered insulin/AMPK signaling pathway?
 
pbandy1 said:
any thoughts on acute caffeine usage potentially reducing Glut4 expression?

study for reference: Acute vs chronic caffeine: Are the effects on insulin sensitivity mediated by altered insulin/AMPK signaling pathway?
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Haven't read the study but I've read a few things regarding caffeine lowering insulin resistance, which would be beneficial
 
Since we all agree Berberine HCL, Banaba, Na-R-ALA, Agmatine, etc are some of the top GDA ingredients, wouldn't SlinMax seem like a logical choice for people looking to put together a stack of those components? Yes, I am a Performax rep, however I am looking at it from more of a convenience aspect.

TF Supplements has SlinMax buy one get one 50% off. That makes it $24.74 a bottle. To me it seems like buying 4 or 5 products and stacking them would be a pita.

At 4 caps per day you would get:
500mg Na-R-ALA
1500mg Agmatine
400mg Berberine
200mg Banaba at 2% Corosolic
Plus the 4-hydroxyisoluecine


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Z28Luver7777 said:
Yea that's essentially the same thing, lowering resistance and increasing sensitivity
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sorry... mistake on my part. I meant that examine shows that acute caffeine intake can increase insulin RESISTANCE in humans.

In the grand scheme of things, not a big deal most likely. Plenty of lean individuals here with high caffeine intake.
 
cubsfan815 said:
Since we all agree Berberine HCL, Banaba, Na-R-ALA, Agmatine, etc are some of the top GDA ingredients, wouldn't SlinMax seem like a logical choice for people looking to put together a stack of those components? Yes, I am a Performax rep, however I am looking at it from more of a convenience aspect.

TF Supplements has SlinMax buy one get one 50% off. That makes it $24.74 a bottle. To me it seems like buying 4 or 5 products and stacking them would be a pita.

At 4 caps per day you would get:
500mg Na-R-ALA
1500mg Agmatine
400mg Berberine
200mg Banaba at 2% Corosolic
Plus the 4-hydroxyisoluecine


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Your killing me, gutta pull out the ol cc now
 
cubsfan815 said:
Haha my bad. I honestly was just saying it's pretty hard to beat that price.

I'm pretty sure you will enjoy it though!
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I have to be carefull with agamatine though, as in the past after several days of use it builds up in my system it causes causes my migraines and epilesy to act up.

Im going to give slinmax a try though as i hadnt used agamtine in over a year due to that issue but this past weekend at the NPC ECC, where i placed 2nd in the novice heavy weight out of 7 guys, i threw 500mg in with my gda stack 15mins before meals and not only did I liked it alot I havnt noticed any side effects yet. Im wondering if it has anything to do with taking it with food as in the past i just took it on an empty stomach pre workout.
 
Z28Luver7777 said:
I'm wondering what's the optimal amount of time prior to a meal to take these supplements?
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15 min to 30 min is the average recommendation on most GDA formulas and bulk powders. I've waited as long as 60-90 min sometimes due to unplanned interruptions that cause me to have to wait a little longer before eating.
 
My current stack:

berberine 500mg
R-ALA 200mg
Cinnamon 4:1 300mg
Chromium polynicotinate 200mcg
Corsolic acid 1.5% 250mg

Thoughts?
 
Z28Luver7777 said:
My current stack:

berberine 500mg
R-ALA 200mg
Cinnamon 4:1 300mg
Chromium polynicotinate 200mcg
Corsolic acid 1.5% 250mg

Thoughts?
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Looks good. Although not necessary, possible additions would be gymnema 75%, vanadyl sulfate and maybe some HCA 50/60%.
 
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