LGD vs OSTA (health biomarkers)
- Thread starter Whacked
- Start date
smith_69
Well-known member
UncleSarm
Well-known member
I just finished a 6 week cycle of Osta at 25mg. Waiting for blood results to come back, so I'll find out if the lipids took a hit or not. As far as lethargy, none. Felt really nice on Osta in every way.
No experience *yet* with LGD. That will be coming up next in a few months though.
Whacked
Well-known member
Any cliff notes on the 204 pages??!! Lol
TheConMan
New member
I've ran osta a few times before, here's my experience based on bloods:
1) Lipids were in normal range post cycle
2) Liver values increased a bit, but you can keep it in check dosing 1.5g NAC on cycle if that concerns you
3) No lethargy for me, but that depends on the individual. If you do experience lethargy, it's most likely gonna happen half way throu cycle. You can mitigate that with a low dose of 4-DHEA
1) Lipids were in normal range post cycle
2) Liver values increased a bit, but you can keep it in check dosing 1.5g NAC on cycle if that concerns you
3) No lethargy for me, but that depends on the individual. If you do experience lethargy, it's most likely gonna happen half way throu cycle. You can mitigate that with a low dose of 4-DHEA
Whacked
Well-known member
Thanks for the feedback!
Hey, future help....TUDCA>NAC for biliary cholestasis (which is typically what occurs in AAS-induced hepatotoxicity)
westcoast001
New member
I would suggest to take an on cycle support when running any sarms to be as safe as possible. Both lgd and osta are suppressive, so depending on what your test levels are to start you may get lethargy and shutdown symptoms or you may not.
anab0lix
Member
Hey, future help....TUDCA>NAC for biliary cholestasis (which is typically what occurs in AAS-induced hepatotoxicity)
So NAC in all cycle supports is basically useless like milk thistle?
UncleSarm
Well-known member
^^^ this. My test dropped by more than 400ng/dl, below minimum, but I was feeling quite good. The sides are quite user dependent.
Westy, what would you recommend for on cycle support?
westcoast001
New member
I really like the look of Lgi Damage Control, but I'm finding very hard to find lately and wondering if it's discontinued. I'm curious about Focused Nutritions On cycle Support supp, it looks pretty good. Other than that tudca is obviously a great one to take on cycle.
UncleSarm
Well-known member
TUDCA is for liver support though. It will not do anything for the suppression or test levels. Or am I wrong?
NoAddedHmones
Well-known member
This the product you referring to?
Ingredients In Cycle Care
SERVING SIZE: 60 Capsules
TUDCA 25mg
ZMA 137.50mg
Hawthorn Berry 150mg
Celery Seed 37.50mg
Saw Palmetto 110mg
N Acetyl L Cysteine 50mg
Milk Thistle 100mg
Pantothenic Acid(vit B-5) 25mg
Toren
Well-known member
TUDCA 25mg
ZMA 137.50mg
Hawthorn Berry 150mg
Celery Seed 37.50mg
Saw Palmetto 110mg
N Acetyl L Cysteine 50mg
Milk Thistle 100mg
Pantothenic Acid(vit B-5) 25mg
^ I would not use a cycle support supplement with that formula for any cycle. It's ingredients are either non-standardized, underdosed, or really underdosed.
westcoast001 If you want something with arimistane, look at OL Arimicare Pro. If you want something without arimistane, look at CEL Cycle Assist. Adding a bit of TUDCA to both is a good idea.
ZMA 137.50mg
Hawthorn Berry 150mg
Celery Seed 37.50mg
Saw Palmetto 110mg
N Acetyl L Cysteine 50mg
Milk Thistle 100mg
Pantothenic Acid(vit B-5) 25mg
^ I would not use a cycle support supplement with that formula for any cycle. It's ingredients are either non-standardized, underdosed, or really underdosed.
westcoast001 If you want something with arimistane, look at OL Arimicare Pro. If you want something without arimistane, look at CEL Cycle Assist. Adding a bit of TUDCA to both is a good idea.
warlordwrug
Member
Grape seed extract and r-ala also combats bilirubin(jaundice)
UncleSarm
Well-known member
Thanks for sharing, but quite honestly I didn't fully understand the article. Does it say that TUDCA increases your metabolic rate, therefore you burn more calories?
How does that work with using it as on-cycle support?
NoAddedHmones
Well-known member
Definitely would not be my take home message from that study.
UncleSarm
Well-known member
It's been a long day and I almost smashed my forehead on the keyboard by the second sentence. Have mercy.
smith_69
Well-known member
UncleSarm NoAddedHmones
TUDCA and 4-PBA are capable of activating the D2 pathway (Dopamine receptor D2- main receptor for all antipsychotic drugs)
Exposure of brown adipocytes (cell specialized for the storage of fat, found in connective tissue) to TUDCA or 4-PBA accelerates the production of T3 (triiodothyronine, aka T3) and stimulates energy expenditure via a mechanism that is D2-dependent.
in mice
ps-
i didnt write this crap, it was like reading Klingon
Sarmy made it further than i did last night
TUDCA and 4-PBA are capable of activating the D2 pathway (Dopamine receptor D2- main receptor for all antipsychotic drugs)
Exposure of brown adipocytes (cell specialized for the storage of fat, found in connective tissue) to TUDCA or 4-PBA accelerates the production of T3 (triiodothyronine, aka T3) and stimulates energy expenditure via a mechanism that is D2-dependent.
in mice
ps-
i didnt write this crap, it was like reading Klingon
Sarmy made it further than i did last night
UncleSarm
Well-known member
Reread the whole article today and I still have no idea what it means. From "stimulates energy expenditure" I am guessing it's some sort of stimulant.
smith_69
Well-known member
thats what im taking from it. however, the study was done on "portly mice"
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Whacked
Well-known member
WTH. So TUDCA (in addition to detoxifying liver) can also assist w depression and increase T3 conversion from T4?
smith_69
Well-known member
its a good question, but when you read the report, the mice were overweight and tud was injected- how much will it actually increase in a human and how much would be needed? If you take the norm recom dose, will it make that much of a difference? when people discuss tud, i have never really read anyone saying the test levels increased solely on Tud alone.
Would I take tud in the hopes this will increase my test alone, no. dont think the results would be the ones people would expect.
smith_69
Well-known member
brofessorx little discussion about tudca and increasing of test- provided an article and looking for a def answer- is this within your realm of knowledge or can you shed a little light on this?