Sildenafil & Tadalafil

I am NOT a doctor so the following is for informational purposes only. The dose you should take is the one your doctor prescribes you!

Viagra:
25 mg, 50 mg 100 mg tablets
Onset of action: 30 minutes (effect delayed if taken with food)
Duration of action: 4 to 5 hours

Cialis:
5 mg, 10 mg, 20 mg tablets
Onset of action: 16-45 minutes (effect NOT delayed by food)
Duration of action: 36 hours

Typical recommended dosage for Cialis is 10mg (5mg if daily use), and 50mg for viagra (though your doctor may lower this amount to 25mg, or increase it up to 100mg).


***ALSO, PLEASE DO NOT TAKE ANY NITRATES, N.O., OR ANY PUMP PRODUCTS WHILE ON EITHER***
 
kboxer7 said:
I am NOT a doctor so the following is for informational purposes only. The dose you should take is the one your doctor prescribes you!

Viagra:
25 mg, 50 mg 100 mg tablets
Onset of action: 30 minutes (effect delayed if taken with food)
Duration of action: 4 to 5 hours

Cialis:
5 mg, 10 mg, 20 mg tablets
Onset of action: 16-45 minutes (effect NOT delayed by food)
Duration of action: 36 hours

Typical recommended dosage for Cialis is 10mg (5mg if daily use), and 50mg for viagra (though your doctor may lower this amount to 25mg, or increase it up to 100mg).

***ALSO, PLEASE DO NOT TAKE ANY NITRATES, N.O., OR ANY PUMP PRODUCTS WHILE ON EITHER***
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Is it safe to take citrulline with Viagra?
 
cia is usually 20-30mg for sexual enhancment, for blood pressure around 5mg and i found CIA to last 2.5 days not 1.5 IMO

i found 15mg a dy enough for 2-3 days. but people differ.
 
Blergs said:
cia is usually 20-30mg for sexual enhancment, for blood pressure around 5mg and i found CIA to last 2.5 days not 1.5 IMO

i found 15mg a dy enough for 2-3 days. but people differ.
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I was just stating the clinical/pharmacological half lives and standard prescription levels. You are correct in that everyone/case is different and dosages > results may vary though.
 
sprintsss said:
Is it safe to take citrulline with Viagra?
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L-Citrulline gets turned into L-arginine in the kidneys, which means It increases NITRIC OXIDE, blood flow, and REDUCES BP.

So the answer is NO, I wouldn't recommend it.

I can cite some studies...but I'm being lazy.
 
kboxer7 said:
L-Citrulline gets turned into L-arginine in the kidneys, which means It increases NITRIC OXIDE, blood flow, and REDUCES BP.

So the answer is NO, I wouldn't recommend it.

I can cite some studies...but I'm being lazy.
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Lmaooo dam I been doing that combo last couple times I guess I'll stop that
 
In regard to taking citrates/no supps, do we mean just not taking them together with tada/sild? Or is it ok if nitrates are dosed in the morning pre workout and the tada/sild dosed at night time?
 
kboxer7 said:
L-Citrulline gets turned into L-arginine in the kidneys, which means It increases NITRIC OXIDE, blood flow, and REDUCES BP.

So the answer is NO, I wouldn't recommend it.

I can cite some studies...but I'm being lazy.
Click to expand...

Mixing citrulline with 25mg Viagra I have not gotten the side effects I get off Viagra when I don't take citrulline

Stuffy nose
Bloodshot eyes
Mild headache

I have not any side effects either of low blood pressure

But on the safe side I'll stop
 
srocco112 said:
In regard to taking citrates/no supps, do we mean just not taking them together with tada/sild? Or is it ok if nitrates are dosed in the morning pre workout and the tada/sild dosed at night time?
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I would consider the half lives of each compound:

4 hours Viagra
17.5 Cialis (but can cause effects up to 36-72 hours later)

A lot of people use both together (and pump products) even though they shouldn't. Can it be done, yes. Should it be? No.
I promise, the day someone gets a sudden drop in BP and goes hypotensive it will be a day they won't forget.
 
sprintsss said:
Mixing citrulline with 25mg Viagra I have not gotten the side effects I get off Viagra when I don't take citrulline

Stuffy nose
Bloodshot eyes
Mild headache

I have not any side effects either of low blood pressure

But on the safe side I'll stop
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Interesting that the combo mediated the side effects.

V has a short half life (4 hours), so I wonder if you dosed Citrulline past those 4 hours if it would help mediate the side effects or if that is too late.

Like I said, people do it. People take pump products with V or C and are ok. But the risk to go hypotensive is there and IF it happens it will be a bad day for sure.
 
kboxer7 said:
Interesting that the combo mediated the side effects.

V has a short half life (4 hours), so I wonder if you dosed Citrulline past those 4 hours if it would help mediate the side effects or if that is too late.

Like I said, people do it. People take pump products with V or C and are ok. But the risk to go hypotensive is there and IF it happens it will be a bad day for sure.
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Understood I did it with intentions there wasn't a bad combo. I know about nitrates didn't know citrulline may have an effect as well.

I literally chug 8 grams of l citrulline with the pill with no side effects at all

Now that u scared me I can't do it again lol

But yes before I would have to use Advil and maybe affrin at times I have not with citrulline mixed in
 
sprintsss said:
Understood I did it with intentions there wasn't a bad combo. I know about nitrates didn't know citrulline may have an effect as well.

I literally chug 8 grams of l citrulline with the pill with no side effects at all

Now that u scared me I can't do it again lol

But yes before I would have to use Advil and maybe affrin at times I have not with citrulline mixed in
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lol yeah, its something you likely wouldn't feel till it is a problem. Could never be a problem, but the day it is it won't be fun.
 
I don't have it for Citrulline, but since we know it is converted to Arginine we can use Arginine as a guestimate:

Bioavailability of L-arginine was 68+/-9 (51-87)%. Clearance was 544+/-24 (440-620), 894+/-164 (470-1190), and 1018+/-230 (710-2130) ml min(-1), and elimination half-life was calculated as 41.6+/-2.3 (34-55), 59.6+/-9.1 (24-98), and 79.5+/-9.3 (50-121) min, respectively.

Blood pressure and total peripheral resistance were significantly decreased after intravenous infusion of 30 g L-arginine by 4.4+/-1.4% and 10.4+/-3.6%, respectively

The onset and the duration of the vasodilator effect of L-arginine and its effects on endogenous NO production closely corresponded to the plasma concentration half-life of L-arginine.

Br J Clin Pharmacol. 1998 Nov;46(5):489-97.
L-arginine-induced vasodilation in healthy humans: pharmacokinetic-pharmacodynamic relationship.
 
kboxer7 said:
I don't have it for Citrulline, but since we know it is converted to Arginine we can use Arginine as a guestimate:

Bioavailability of L-arginine was 68+/-9 (51-87)%. Clearance was 544+/-24 (440-620), 894+/-164 (470-1190), and 1018+/-230 (710-2130) ml min(-1), and elimination half-life was calculated as 41.6+/-2.3 (34-55), 59.6+/-9.1 (24-98), and 79.5+/-9.3 (50-121) min, respectively.

Blood pressure and total peripheral resistance were significantly decreased after intravenous infusion of 30 g L-arginine by 4.4+/-1.4% and 10.4+/-3.6%, respectively

The onset and the duration of the vasodilator effect of L-arginine and its effects on endogenous NO production closely corresponded to the plasma concentration half-life of L-arginine.

Br J Clin Pharmacol. 1998 Nov;46(5):489-97.
L-arginine-induced vasodilation in healthy humans: pharmacokinetic-pharmacodynamic relationship.
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Not good with this type of stuff bro so half life is around an hour give or take ?
 
sprintsss said:
Not good with this type of stuff bro so half life is around an hour give or take ?
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That's what I'm extrapolating from that study.

However, I don't know exactly how long it takes the kidneys to process Citrulline into L-Arginine, so that time would need to be added as well.
 
For those interested:

I was able to find data that after ingestion, plasma nitrate begins a steep spike starting at about 30min and rising to a peak lasting from hours 1-3 post ingestion. From that point, a very gradual decline happens up to hour 6 post ingestion, after which a STEEP drop off occurs.

Since Nitrates are also NOT TO BE TAKEN WITH CIALIS OR VIAGRA

Invalid Link Removed
 
kboxer7 said:
For those interested:

I was able to find data that after ingestion, plasma nitrate begins a steep spike starting at about 30min and rising to a peak lasting from hours 1-3 post ingestion. From that point, a very gradual decline happens up to hour 6 post ingestion, after which a STEEP drop off occurs.

Since Nitrates are also NOT TO BE TAKEN WITH CIALIS OR VIAGRA

Invalid Link Removed
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If you consider the scale of that graph it is actually a very gradual drop off from the 6 hour mark before reaching a low at the 24 hour mark.
 
NoAddedHmones said:
If you consider the scale of that graph it is actually a very gradual drop off from the 6 hour mark before reaching a low at the 24 hour mark.
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Good catch.

Not a very steep drop off at all.
 
Sildenafil & Tadalafil

hamdysayed said:
Damnnnnn alot of PPL with ED here hehe jk.
but for real tho why ppl need that ?
Is it from the cycles ?
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A lot of people take it while on cycle due to libido drop. Some stims can also affect performance.

I'll also add that the refractory period between "sets" if you will, gets longer as we age. V & C can help you go from needing 15/20min between rounds to 2-5 for example.
 
Sildenafil & Tadalafil

Volvo140G said:
Remember to call your doctor if you have an erection lasting more than 4 hours.
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So he/she can tell you to go to the hospital and get your penis aspirated. That would not be enjoyable.
 
kboxer7 said:
A lot of people take it while on cycle due to libido drop. Some stims can also affect performance.

I'll also add that the refractory period between "sets" if you will, gets longer as we age. V & C can help you go from needing 15/20min between rounds to 2-5 for example.
Click to expand...

Not everyone uses them because they cant get it up, but rather they just want to get it up even more. Peace of mind. Reduce performance anxiety. Or due to effects from certain supps such as hormones or extensive stim use.

I myself find i can use it every now and then about now because im in my 12th week of ECAY and am a bit burnt out. Hell, during normal times 2.5mg of yohimhine gives me rock hard wood that it actually hurts (her and me lol). But right now due to how long i been on in addition to low caloric diet, find myself just not as powerful certain nights.

Nothing wrong with taking 1 once in a while to help a temporary side effect. You take an anti biotic when sick right?

I only asked for dose suggestions because its been years since iv used tadalafil and wanted to make sure i remembered correctly.

This post is in respond to the previous question about why people need/use it.
 
sprintsss said:
Lol I'm from miami bro
I deal with hispanic women pulling all nighters

I don't take Viagra to accomplish couple positions in 15 minutes
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All nighters wtfff, why the hell u gonna be doing that, where is the fun lol just fukin allll night oO...
Or we r talking couple hpurs? That I'll understand .
 
hamdysayed said:
All nighters wtfff, why the hell u gonna be doing that, where is the fun lol just fukin allll night oO...
Or we r talking couple hpurs? That I'll understand .
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Cardio bro....cardio.
 
Golden root complex is awesome and it's natural. I am on it nd it's very good with no unwanted sides
 
kboxer7 said:
I would consider the half lives of each compound:

4 hours Viagra
17.5 Cialis (but can cause effects up to 36-72 hours later)

A lot of people use both together (and pump products) even though they shouldn't. Can it be done, yes. Should it be? No.
I promise, the day someone gets a sudden drop in BP and goes hypotensive it will be a day they won't forget.
Click to expand...
The BP reducing effect of citrulline is not very strong from my experience.Only thing i would definetely stay away from whilst taking Viagra or cialis are rx nitrates
 
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