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Gaba Study

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quadruples post-training growth hormone production

GABA quadruples post-training growth hormone production

Strength athletes who take 3 g of the supplement GABA [structural formula shown below] quadruple their growth hormone production during and after a training session. Sports scientists at Shenandoah University discovered this when they did an experiment with 11 men (average age 23), all of whom were regular weight lifters.

GABA – gamma-aminobutyric acid in full – is a neurotransmitter found primarily in the brain. The body makes the compound from glutamate. GABA plays a role in relaxation; sedatives and sleeping pills like benzodiazepines and barbiturates work via the same receptor as GABA does. GABA is available on the market as a supplement, but you have to take huge amounts to notice any effect, as the brain cannot absorb it easily from the blood.

GABA stimulates the brain's production of growth hormone. Strength training does the same. The researchers wondered what happens if you do both: would the production of growth hormone increase even more?

The researchers got their subjects to train their main muscle groups, doing chest presses, lat pull downs, flies, seated rows, shoulder presses, biceps curls, triceps extensions, leg-presses, leg-curls, leg-extensions and calf-raises. The subjects trained using 70 percent of the weight at which they could just manage 1 rep, doing 1 set of each exercise and resting for 1 minute between sets. The training session lasted 15 minutes.

On one occasion the subjects took 4 caps of GNC's GABA-750 [each cap contained 750 mg GABA], and on the other they took caps containing no active ingredient. The researchers repeated the procedure while the subjects rested. Even when the men were not training the GABA supplement raised their growth hormone level.

GABA quadruples post-training growth hormone production
The figure below shows levels of immuno-reactive GH. This is the fraction of growth hormone that is biologically active.

The researchers monitored the subjects' blood for 90 minutes. The figure below shows the total amount of active growth hormone the subjects made during the period.

GABA quadruples post-training growth hormone production
GABA increased the total amount of growth hormone the subjects made as a result of training by 480 percent. Whether strength athletes would lose fat or build up more muscle quicker in the long term as a result of this effect, the researchers do not yet know.
 
GH has much more an effect on fat loss than muscle growth. Even then, its take a long time with even injectable GH to have an effect. Not saying there isn't anything to this, as many of these supplements taken for prolonged periods of time might show an effect, but nothing within 4-6 weeks I would suspect.
 
GH has much more an effect on fat loss than muscle growth. Even then, its take a long time with even injectable GH to have an effect. Not saying there isn't anything to this, as many of these supplements taken for prolonged periods of time might show an effect, but nothing within 4-6 weeks I would suspect.

Pretty much this!
 
I used to take 5g before bed. Would get tingling sensations in my limbs followed by shortness of breath for maybe ten minutes. After that subsided I would pass out like a rock for a solid 8-9 hours. That is awesome for a guy like me who has trouble staying asleep for more than 6 hours at a time. I like GABA for sleep quality rather than GH benefits. Wish Nutraplanet still had this in bulk.
 
Would be interested what the cause of the breathness shortage is AS i experienced it also.i think ala is a bit similar in this regard
 
Would be interested what the cause of the breathness shortage is AS i experienced it also.i think ala is a bit similar in this regard

"Overdose" of GABA would cause shortness of breath, increased anxiety and numbness
Not 100% why it happens but one thing is for sure. As overdose of GABA could increase anxiety, anxiety could lead to shortness of breath
 
"Overdose" of GABA would cause shortness of breath, increased anxiety and numbness
Not 100% why it happens but one thing is for sure. As overdose of GABA could increase anxiety, anxiety could lead to shortness of breath
Yes^^^. It happened every time I would go over 2 g. I knew I was dosing high and expected the sides. Honestly it wasn't a deal breaker as I had huge improvements in sleep quality and it would subside quickly. It was worrisome the first time I noticed it. After knowing what to expect the anxiety went away.
 
I feel this shortness of braeth even at 1 g and imho it does not feel as its anxiety related has to be something else
 
Saw that on either Ergo-Log, or Suppversity, forget which. I'm with everyone else. But it's pretty cheap - 30 (3g) pre-workout doses is about $10, if you wanted to experiment. ...But that's also a can of Fearn's :)
 
GH has much more an effect on fat loss than muscle growth. Even then, its take a long time with even injectable GH to have an effect. Not saying there isn't anything to this, as many of these supplements taken for prolonged periods of time might show an effect, but nothing within 4-6 weeks I would suspect.

Even if you took it for 6 months, it would be virtually worthless for you ;)
 
In gaba or just any GH "booster"?

I found a nice abstract study on GABA:

"The effect of GABA on penile enlargement"
Rosenberg IR, et al. Ann Surg. 2012

Authors

Rosenberg IR,*Zambrano VJ,*Janowitz HD,*Rudick J.

Citation

Ann Surg. 2012 Mar;183(3):247-51


:D
 
Any GH booster if you're looking for is fat loss or increased LBM

I would never look for muscle gain from a GH product, but fat loss (not comparing to an actual fat burner) might occur in older individuals that have an increased drop due to aging. But I also believe this could be helped simply by diet alone.
 
I would never look for muscle gain from a GH product, but fat loss (not comparing to an actual fat burner) might occur in older individuals that have an increased drop due to aging. But I also believe this could be helped simply by diet alone.

Most people here are not in the senior/ geriatric population, so I don't consider that group when I discuss research here :)
 
Most people here are not in the senior/ geriatric population, so I don't consider that group when I discuss research here :)

I don't have to take that!!! :lol:

Ok, maybe I do.
 
I have NEVER been into nootropics or this type of thing, until I bought some last week. Been experimenting - started with 1 gram and then my GF got sick and I wound up staying up all night while she was in the ER. I then spent the night at the hospital with her, took a gram, passed into deep sleep until a nurse game barging in and woke us up - and I couldn't get back to sleep for 2 hours. The next night, I spent in the hospital with her again, and I took 2 grams and passed out for a solid 8 hours...nothing woke me up. Didn't realize anything was going on. Last night, we were home so I took 3 grams....passed out for a few hours and woke up again. Even at 3 grams I've not noticed any tingling or anything. I am using NOW Gaba...so I'm sure it's legit.

I will say that, particularly yesterday, I just feel happier, better, etc. Late yesterday, when I normally crash, I suddenly had a lot of energy. This could be because I got the first night of deep deep sleep that I've had in a long time. Ironic that it happened in a hospital.

I'm interested in this stuff - particularly because it doesn't cross the BBB yet seems to have an effect anyway. It's interesting for sure.
 
I have NEVER been into nootropics or this type of thing, until I bought some last week. Been experimenting - started with 1 gram and then my GF got sick and I wound up staying up all night while she was in the ER. I then spent the night at the hospital with her, took a gram, passed into deep sleep until a nurse game barging in and woke us up - and I couldn't get back to sleep for 2 hours. The next night, I spent in the hospital with her again, and I took 2 grams and passed out for a solid 8 hours...nothing woke me up. Didn't realize anything was going on. Last night, we were home so I took 3 grams....passed out for a few hours and woke up again. Even at 3 grams I've not noticed any tingling or anything. I am using NOW Gaba...so I'm sure it's legit.

I will say that, particularly yesterday, I just feel happier, better, etc. Late yesterday, when I normally crash, I suddenly had a lot of energy. This could be because I got the first night of deep deep sleep that I've had in a long time. Ironic that it happened in a hospital.

I'm interested in this stuff - particularly because it doesn't cross the BBB yet seems to have an effect anyway. It's interesting for sure.

I hope your GF is better :)
 
I hope your GF is better :)

Yes thank you. She just had a stomach virus and needed fluids and antibiotics. But let's focus on the important stuff - supplements. haha. J/k. Thanks for asking :)
 
GH has much more an effect on fat loss than muscle growth. Even then, its take a long time with even injectable GH to have an effect. Not saying there isn't anything to this, as many of these supplements taken for prolonged periods of time might show an effect, but nothing within 4-6 weeks I would suspect.

Completely agree with you. a daily ZMA + gaba dose prebed i like though
 
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