Ostarine tissue selectivity and Gyno

[jbryand101b]

I dug around a bit an found out that the increase in prolactin from daa is proportional to the increase in test.

Does suppression also cause a decrease in prolactin? If that is the case, should daa not return prolactin closer to baseline along with test, leaving the ratio of the two about the same?

Daa isn't going to help with test production during suppression from steroids.

Something people need to remember.
Sarms bind to the androgen receptor, they have activation, but like a serm blocks estrogen from binding/interacting, sarms will block and compete with androgens from binding.

This is a whole new area, sarms are still being studied, so all if us using them are guinea pigs, figuring out what they do to us.

I like to use a low dose in pct. Osta was effective at 3mg.
I used 6mg coming off a long cycle, and it helped maintain strength and hardness while in pct. Was definitely noticeable coming off the sarm to run letro an Clomid alone.
No sides were experienced in the low dose, and it was a good experience.

Running it solo I would chock that up with using trt dosages for a cycle, and not worth my trouble unless I was on trt.

 

[BertBolic]

That explains why an androgen/estrogen imbalance may cause gyno.

That brings me back to the thread title. Ostarine works selectively (more effective in some tissues like skeletal muscle and leas effective in others like the prostate). It could also be less effective in breast tissue.

If that is the case, aromatization in the beginning of a cycle + no effective exogenous androgen in breast tissue = gyno?

Also, why do you think that daa will not be effective? You think it is just too weak?

 

[mgkoret]

^^ Thanks for the correction. I wasn't paying total attention to that. I meant that a test base helps with the sides. Not kick starting your own test.

 

[Danes]

^^ Thanks for the correction. I wasn't paying total attention to that. I meant that a test base helps with the sides. Not kick starting your own test.

"You're taking exogenous testosterone as a base because without it, you will be incredibly testosterone deficient. Let's say you take epistane, your body thinks that is testosterone and thus it stops producing testosterone. But epistane is NOT testosterone and acts differently from testosterone. So what happens? Certain functions which needs testosterone is not going to have the testosterone there to support it, there will also not be much testosterone for your body to convert into estrogen and DHT so you will be deficient in those as well.

You take ANY exogenous hormone in big enough doses, your body will self regulate. Period. Other than test and 4-dhea/andro, none of the other PH or steroids are going to give you the equivalent of testosterone in the body, so you will be testosterone deficient, that is why you use a test base."

Thats why libido issues,lethargy and other sides comes if not using test base

 

[BertBolic]

Suppressed T can lead to lower E and DHT too.
I have heard some people reported E sides from supps. But when they took bloodwork, E Levels was more than fine.
Personaly i dont think ostarine would give Estrogen sides. I am not sure about prolactin.

Some of my friends complained about E sides from supps. But bloodwork showed low levels of iodine. After supplementing with iodine, gyno symptoms went away.

Well, I guess it is possible. I do not cook with salt and I do avoid salty foods.

 

[BertBolic]

I just found out that an underactive tyroid can cause elevated levels of prolactin. I was definitely suppressed during my last week on the cycle and I have no lump directly behind the nipple.

I wonder if the puffy nipples were caused by suppression induced prolactin.

Feel free to correct my endocrinology if I am wrong and you are certain that you are right.

 

[jbryand101b]

That's probably why it's recommend to take t3 in small dosages while on tren.

Patrick Arnold had a article on steroids and thyroid function.

Long story short, they have a negative impact

 

[highlander31]

Im also curious about thoughts on DAA during cycle to keep test *higher* than without DAA since DAA actions would be useless on the hypothalamus, but DAA also acts directly on Leydig cells to signal for Test production.

Or would this little bit be trivial and just possibly increase prolactin and estrogen, which would just make it all risk and no reward?

 

[BertBolic]

There are some blood test results posted on another forum that show DAA increased estrogen by more than it increased test, so it may not be a good idea..