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Gyno research/ Can androgens help gyno

SPS said:
I do not get Wtf the arguing is about. So it is generally accecpted dht reduces/may eliminate gyno. They argue their modified dhea converts dht. Therefore their dhea reduces/eliminates gyno. It seems logical, is the issue it doesn't convert to dht? Or it does but not enough to be effective? I don't understand what the beef is.
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The beef is that it can not eliminate gyno. Not even pharma AI's can do that.
 
Rhadam said:
The beef is that it can not eliminate gyno. Not even pharma AI's can do that.
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Once you have gyno only surgery really eliminates it. A dht or pharma Ai will only prevent/slow gyno and eliminate itchy puffy swollen nips
 
Tovok123 said:
ive had slight gyno for like 3 months now and my left nipple has been really puffy and lumpy, been taking bulk up for 11 days now and its no where near as puffy anymore and is quite hard...gyno is still there, but honestly it feels/looks better. I will see how it all pans out over the cycle, but oh lord if it gets worse in pct i will murder AF. haha
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Please don't do that :)
The reducing effects you're seeing are exactly what I was taking about.
If it goes away and then comes back in pct, that is due to an estrogen rebound. That can simply be avoided with a decent AI. Read-avoided, as in start that AI immediately in PCT instead of waiting for the sides to show up and then try chasing estrogen. That's always a losing battle.
 
There are a lot of really good post in these threads. I appreciate you guys taking the time to break it down and have a full detailed conversation for everyone. There are a lot of studies that show the DHT and DHEA can help with gyno and everybody's situation is different.
 
I can't post links so here is the title at the bottom and here is a quote. This also applies to letrozole. I read the full text on the letrozole study and the concentrations one can achieve in the skin, and breast tissue are much higher via transdermal.

I bet it still wont be enough to get rid of old gyno but will be more helpful than oral and will avoid side effects.

"High accumulation of the drug in the skin and muscle tissue beneath the patch application site was observed in mice compared with that after oral administration. These findings show that anastrozole transdermal patches are an appropriate delivery system for application to the breast tumor region for site-specific drug delivery to obtain a high local drug concentration"



[h=1]Transdermal patches for site-specific delivery of anastrozole: In vitro and local tissue disposition evaluation.[/h]
 
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