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Half Life of Androgel. Why 1.62% Applied only to Upper Arms & Shoulders?

ratdog

New member
I have a couple of questions for guys that have used or are using Androgel for HRT. How long do the effects of the gel last? I am trying to split my dose in 2 parts, one in the morning and one in the afternoon. I really feel the effects about two hours after applying, but wonder how long the testosterone levels stay up or how fast it falls in a 24 hour period. Several years ago, I was prescribed Androgel 1%, and was told to apply to my upper arms/shoulders and abdomen. Now I have been prescibed 1.62% and am only supposed to apply it to upper arms/shoulders and NOT to the abdomen. Is this to minimize exposure/transfer to females? If I am showering before bed every night could there be any harm in applying the higher strength to my abdomen as well?
 
abdomen application is an exposure issue , you are were correct in your assumption, half life I am not sure, I apply the whole dose early in the morning and my highest levels seem to be late afternoon
 
james122 said:
abdomen application is an exposure issue , you are were correct in your assumption, half life I am not sure, I apply the whole dose early in the morning and my highest levels seem to be late afternoon
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Abdominal application will increase conversion to estrodial. It drys in 2 hours so you can workout and shower. Just apply it once during the day time and it will mimic the natural daily out put of testosterone during the day time. Do not try to over analyze some thing so simple..Every one metabolizes testosterone differently.
 
Hi Matrix, Thanks for your input. Since the application instructions that come with the Androgel 1% tell you to apply to abdomin, why would you say "Abdominal application will increase conversion to estrodial" ? Thanks
 
The Matrix said:
Abdominal application will increase conversion to estrodial. It drys in 2 hours so you can workout and shower. Just apply it once during the day time and it will mimic the natural daily out put of testosterone during the day time. Do not try to over analyze some thing so simple..Every one metabolizes testosterone differently.
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Wow thats interesting , my doctor has always told me that it is an exposure issue, and my estrodiol is always in check, but this makes me wonder if it would be lower if I applied it elsewhere, where woould you suggest matrix? arms and shoulders?
 
james122 said:
Wow thats interesting , my doctor has always told me that it is an exposure issue, and my estrodiol is always in check, but this makes me wonder if it would be lower if I applied it elsewhere, where woould you suggest matrix? arms and shoulders?
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Upper shoulders and biceps (just not on same arm as blood draw
Rubbing it on abs their is a higher percent of body fat and more likely more estradiol conversion occuring as I have seen in the past with clients.
 
The Matrix said:
Upper shoulders and biceps (just not on same arm as blood draw
Rubbing it on abs their is a higher percent of body fat and more likely more estradiol conversion occuring as I have seen in the past with clients.
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I have tattoos on both upper arms.. Only the INNER biceps (where touches lats/sides) are un inked... Will applying the gel to the tattoos a) cause them to fade? B) reduce the effectiveness of the gel? I have been applying to sides/obliques so as to avoid stomach hair (I don't shave year round lol) and feel like estro sides are goingup... Bloods aren't until Jan :(



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ALSO--- I hAve been instructed to apply at night before bed (11pm) bc I do not wake up at the sane Time every morning bc I am a student and waiter... So the only way i can get a 24 dosing schedule is to do it at night... Is this ok in your opionikn matrix?
 
here was a study concerning exposure, absorption and different application sites go to rx list website and search androgel 1.62 : http www .rxlist.com/androgel-162-drug/clinical-pharmacology.htm
 
chedapalooza said:
I have tattoos on both upper arms.. Only the INNER biceps (where touches lats/sides) are un inked... Will applying the gel to the tattoos a) cause them to fade? B) reduce the effectiveness of the gel? I have been applying to sides/obliques so as to avoid stomach hair (I don't shave year round lol) and feel like estro sides are goingup... Bloods aren't until Jan :(

<img src="http://anabolicminds.com/forum/attachment.php?attachmentid=70757"/>

<img src="http://anabolicminds.com/forum/attachment.php?attachmentid=70758"/>

<img src="http://anabolicminds.com/forum/attachment.php?attachmentid=70759"/>

ALSO--- I hAve been instructed to apply at night before bed (11pm) bc I do not wake up at the sane Time every morning bc I am a student and waiter... So the only way i can get a 24 dosing schedule is to do it at night... Is this ok in your opionikn matrix?
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Curious about the night application too
 
lexmuscle said:
Curious about the night application too
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I've been considering adding a pump of Thr gel (20mg test ) to my one patch (2mg)

Only 2 mg of gel will get absorbed, so that should in theory equal the 4mg patch I was having amazing results with... Since being dropped back to 2 mg patch, I don't feel nearly as well.
 
i believe i read using gel in the morning mimmicks the natural morning testosterone spike and perhaps the thought is to not supress that natural production spike by "sneaking" in the xtra boost from exogenous gel while its happening. similarly, bodybuilders use this tecnique with low dose dbol when coming off a cycle called bridging. I think i remember reading estrogen spikes at night so it was best to take anti-e's at that time and i would guess the test could aramotize and add to that natural e-spike if taken at night plus gh spikes at nite and i thought exogenous testosterone supresses gh production?? although i would still try and spread out the gel just to keep the blood levels more stable.. say 2 pumps when u wake up and 2 pumps after dinner.. androgel is released over a 24 hr period per the spec sheet from their site.
 
abs322 said:
i believe i read using gel in the morning mimmicks the natural morning testosterone spike and perhaps the thought is to not supress that natural production spike by "sneaking" in the xtra boost from exogenous gel while its happening. similarly, bodybuilders use this tecnique with low dose dbol when coming off a cycle called bridging. I think i remember reading estrogen spikes at night so it was best to take anti-e's at that time and i would guess the test could aramotize and add to that natural e-spike if taken at night plus gh spikes at nite and i thought exogenous testosterone supresses gh production?? although i would still try and spread out the gel just to keep the blood levels more stable.. say 2 pumps when u wake up and 2 pumps after dinner.. androgel is released over a 24 hr period per the spec sheet from their site.
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Yea but if it wears off due to rubbing on clothes or sweating during workout, you lose that dose in a way...
I couldn't use the gel as my sole trt it just didn't work well enough for me. Im THINKING of doing one pump in am and then changing my patch at night like I already do on a nightly basis...
 
chedapalooza said:
Yea but if it wears off due to rubbing on clothes or sweating during workout, you lose that dose in a way...
I couldn't use the gel as my sole trt it just didn't work well enough for me. Im THINKING of doing one pump in am and then changing my patch at night like I already do on a nightly basis...
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I'm so sick of TRT lol
 
lexmuscle said:
I'm so sick of TRT lol
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well the thought of IM pinning once a week for life is not encouraging either, can u imagine doing this crap every week at 50,60,70, 80 90 yeras old? forget that lol!! can you imagine the scar tissue that would develop, even with rotating sites, giving a shot every week for 10-30 years straight???
 
abs322 said:
well the thought of IM pinning once a week for life is not encouraging either, can u imagine doing this crap every week at 50,60,70, 80 90 yeras old? forget that lol!! can you imagine the scar tissue that would develop, even with rotating sites, giving a shot every week for 10-30 years straight???
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Well at 80/90 I'm not so sure your test levels will be very relevant or important lol but yea not a nice thought... Perhaps better advances will have been made by then... Maybe an oral! Lol
 
there is an oral waiting for FDA approval, it's supposed to be similiar to andriol with better absorption
 
add http clarustherapeutics.com/content/product-development/overview.htm

add http hrt-rx.com/2011/04/11/oral-testosterone-med-on-the-way/
 
abs322 said:
well the thought of IM pinning once a week for life is not encouraging either, can u imagine doing this crap every week at 50,60,70, 80 90 yeras old? forget that lol!! can you imagine the scar tissue that would develop, even with rotating sites, giving a shot every week for 10-30 years straight???
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Using higher gauge needles won't cause scar tissue don't spread misinformation. There are plenty of diabetics who properly rotate sites and minimize bolus size who safely inject insulin DAILY for DECADES without significant scar tissue development.
 
first i wouldnt inject test with insulin needles so what diabetics do is irrelevent. I understand this sub-q trt seems to be the craze but i believe in IM injects in either glutes, quads or delts with test/aas. I would use 22g 1.5" for glutes, 25 g 1" for delts and quads.. if you dont think that will give you scar tissue after 10-30 years of weekly injects you're a fool.
 
Depends how often you inject, if you inject IM weekly or EOD you can even use tiny 29 gauge .5 ml pins since volumes are small and 1 inch is plenty for glutes.check out this thread for more info on a full injection protocol //tnation.t-nation.com/free_online_forum/sports_training_performance_bodybuilding_trt/trt_protocol_for_injections
 
I use 25g 5/8" for quads and delts, straight into muscle. Used to do glutes this way too, I just don't like glute shots even though they're painless.
 
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