Simply put, PowerFULL is known to induce significant increases in growth-hormone production. As the name suggests, growth hormone is an important agent in repair and growth processes. Consequently, additionally stimulating the secretion of growth hormone beyond normal (non-supplement-induced) secretion, may negatively influence growth dynamics in cases where the growth process is not yet completed. While this is not to suggest that the growth trajectory ends at 21, it is a precautionary recommendation consistent with general practice.
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