Yohimbine Homebrew

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    Curt, I think there are blood vessels in the fatty areas of the skin and they are about the same density as the leaner layers but because of the fat, DMSO may not be able to penatrate as well and get to the blood vessels.. Dang, I wish I had my Grey's Ant. book here at the house tonight... left it in my classroom...

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    Can you look into that and get back to us. Talk to ya
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    I will attempt to remember Curt.. any area's in particular you want me to look at?
    •   
       

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    If the DMSO will penetrate the fat. Or if it will get too much in to the blood... Talk to ya..
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    Well I go the menthol. I am going to try to disolve 66g of menthol in 100ml of ISO. It is not as soluable in ISO as it is in water but I am going to try... If it does not work I will try water next.... Talk to ya...

    PS I tried disolving a little in some ISO last night and it disolved but it was not very much. 1-2grams or so.. Talk to ya....
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    Try dissolving it in 90% iso and 10% water...or, some ratio like that until it dissolves. As long as the water content doesn't get too high it shouldn't adversely affect the absorption or mix of the other ingredients. If we find that a water / iso mix is best we might be able to go with cheaper OTC alcohol instead of the 99%...

    Chemo
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    Yes but that will change the final % that i am trying for. It is based on menthol in ISO...Going for 75% solution.... SO I would have to redo all the math(well not me).. I will try the ISO only first if that does not work then we will recalculate.. Talk to ya... Maybe I will get her just to recalculate with water... Talk to ya...

    All I want is a 75% solution. that's all....
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    Originally posted by curt2go
    Well I go the menthol. I am going to try to disolve 66g of menthol in 100ml of ISO. It is not as soluable in ISO as it is in water but I am going to try... If it does not work I will try water next.... Talk to ya...

    PS I tried disolving a little in some ISO last night and it disolved but it was not very much. 1-2grams or so.. Talk to ya....
    I am retarded it is the yom that is not so soluable in water. Menthol is soluable in ISO very well...

    So I put 66g of menthol in 100ml ISO for a 75% solution. It worked no problem. BUT MAN IT IS MENTHOLY.. LIKE I MEAN MENTHOLLY.... Well next I must get the YOM. ANyone want to send me any.... Talk to ya...
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    Curt.. still no luck on finding about how much DMSO is absorbed through fat... I am still looking though.. might take a few days.. dang work is piling thing on me right now
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    Curt2go

    Did you get your put together. I ask because you said the solution was really menthally. If you have finished yours, my question is this something you could have on under cloths or is night application the only option. Provided of course you have nothing planned with a sensitive nosed female. LOL Let me know if you would. I am ordering next week.
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    Another transdermal, $ 135.00 per 8 oz

    Penetrating Gel
    Emulsifies Fat
    On Contact

    Dissolves Deep-Stored Body Fat
    Wherever Applied




    Ingredients:
    Lecithin
    Water
    Octyl Palmitate

    Alcohol

    Glycerin

    Amino Phylline
    Ethylenediamine
    Carbomer

    Citric Acid

    Propyl Gallate

    Forskolin

    DMDM Hydantion
    Yohimbe
    BHA


     








     

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    Interseting. Who makes it. Too many chems to copy but it may help. Good find.. Talk to ya..
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    It's made by Klein-Becker. I had to call to get
    the ingredients, they are not listed on the websight.
    http://www.anorexclick.com/products/dermalin/index.asp
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    If the objective is:
    1. Increase cyclic adenosine monophosphate (cAMP)
    2. Inhibit the production of phosphodiesterase (PDE)
    3. Block alpha 2 adrenergic receptors
    4. Lose love handles (hopefully)
    Could you take forskolin and caffine orally, then yohimbine by
    itself in a transdermal?

     

     

     
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    Originally posted by Hammer
    It's made by Klein-Becker. I had to call to get
    the ingredients, they are not listed on the websight.
    http://www.anorexclick.com/products/dermalin/index.asp
    Klein-Becker are scamers! They suck donkey dong. All ther topical formula does is act like a diuretic. Prepreation-H will do the same thing. Klein-Becker= $100.00 A-hole gel.
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    Another products ingredients. This is the first one I've seen with
    Usnic Acid. I thought UA was most effective when taken into the
    bloodstream. What would be the rational for putting it into a transdermal
    if the purpose of the transdermal was to disperse in fat tissue?

    Ingredients: Water, Peg-100 Stearate, Glyceryl Stearate, Stearyl Alcohol, Carylic/Capric Trigylceride, Caffeine (2% w/w), Sodium Benzoate, Cyclomethicone, Dimethicone, Hydrogenated Lecithin, Benzyl Alcohol, Acrylates/C 10-30 Alkyl Acrylate Crosspolymer, Imidazolidinyl Urea, Triethanolamine, Yohimbe HCL, Forskolin, Usnic Acid and Aminophylline, Methylparaben, Propylparaben, Fragrance/Cinnamon Spice.

    Price $25.79 240 ml

     
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    Originally posted by GYM1
    Curt2go

    Did you get your put together. I ask because you said the solution was really menthally. If you have finished yours, my question is this something you could have on under cloths or is night application the only option. Provided of course you have nothing planned with a sensitive nosed female. LOL Let me know if you would. I am ordering next week.
    My wife smokes Newports, so this sounds like the mixture for me. She'd never even know I had it on.
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    curt: how'd the mix work out for you? any results yet?
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    Originally posted by Hammer
    Another products ingredients. This is the first one I've seen with
    Usnic Acid. I thought UA was most effective when taken into the
    bloodstream. What would be the rational for putting it into a transdermal
    if the purpose of the transdermal was to disperse in fat tissue?

    Ingredients: Water, Peg-100 Stearate, Glyceryl Stearate, Stearyl Alcohol, Carylic/Capric Trigylceride, Caffeine (2% w/w), Sodium Benzoate, Cyclomethicone, Dimethicone, Hydrogenated Lecithin, Benzyl Alcohol, Acrylates/C 10-30 Alkyl Acrylate Crosspolymer, Imidazolidinyl Urea, Triethanolamine, Yohimbe HCL, Forskolin, Usnic Acid and Aminophylline, Methylparaben, Propylparaben, Fragrance/Cinnamon Spice.

    Price $25.79 240 ml

     
     

    Can you tell me where this product is located? URL?  I am looking into doing some testing with Y-HCL/UA transdermals and would like to see if this product has any feedback thus far.

     

    Thanks

    WYD
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    Biolabs offers sculpting gel with the following ingredients:

    Ingredients: Purified water, aminophylline, yohimbe extract, coleus forskolin extract, usnic acid, phospholipids, carbomer, triethanolamine, diazolidinyl, urea, methyl paraben, fragrance, propyl paraben.

     

    I would venture to say that the product probably isn't all that effective because they are using Y-extract instead of Y-HCL and the amount of usnic acid is probably rather low... I wish they gave dosages...
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    another product called lipoburn by SAN

    H2O, Coleus Forskohlii, Usnic Acid, Yohimbe HCL, Aminophylline, Aloe Vera, Eucalyptus Globulis, IBM, NMP, Azone.

     
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    The formula that is in this thread will work good. GYM1 was testing it but he has never got back on how it worked. Maybe it killed him?... The brew mixes well. I have made just the gel and it rubs in awsome.. Give it a try and let us know.. Talk to ya...
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    Originally posted by curt2go
    The formula that is in this thread will work good. GYM1 was testing it but he has never got back on how it worked. Maybe it killed him?... The brew mixes well. I have made just the gel and it rubs in awsome.. Give it a try and let us know.. Talk to ya...
    I read over about 50 different formulas throughout this thread.  Can you post the form that you finally settled with?

     

    Thanks

    WYD

     
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    There you go...

    48% aloe gel 
    25% water
    15% menthol(in alcohol) 75%solution
    10% PG
    2% DMSO
    Y-hcl 3.5g for 1month supply


    To make the menthol solution :

    Disolve 66g of menthol crystals into 100ml of ISO and you get a 75% menthol solution....

    Let us know how it works out... Talk to ya...
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    [QUOTE]Originally posted by whosyourdaddy02
    [B]

     

    Can you tell me where this product is located? URL?  I am looking into doing some testing with Y-HCL/UA transdermals and would like to see if this product has any feedback thus far. 

     
     It is made by a company called Vyo-Tech and the product is Ab-Solution Plus. You can view the info on bb.com or vyotech.com.

    Hammer

     
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    Originally posted by curt2go
    There you go...

    48% aloe gel 
    25% water
    15% menthol(in alcohol) 75%solution
    10% PG
    2% DMSO
    Y-hcl 3.5g for 1month supply


    To make the menthol solution :

    Disolve 66g of menthol crystals into 100ml of ISO and you get a 75% menthol solution....

    Let us know how it works out... Talk to ya...
     

    Thanks for the formula.  What is the dosage of y-hcl per application?  Was it intended to go on twice per day?   I am thinking about adding in some UA and maybe some caffeine,forskolin, and aminophylline, but I need to do the math and figure out how much should go in the bottle and how much will be delivered per application. 

    Thanks

    WYD
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    Some more stuff to consider after discussing with NDN-Diablo

    1.  UA probably wouldn't be very effective in a transdermal because of its need to get into the mitochondria of the cells to be effective.   With the proposed transdermal formula, little would be getting into the bloodstream (as I understand it).  It would help a little, but not nearly as much as oral or with a different transdermal formula.

    2. NDN thought that around 500mg would be a bit too much to take in 1 application.  It would be hard to deliver that much through the skin.  I'm not the transdermal expert, so if someone could elaborate on this point, I'd appreciate it. 

    3. We discussed the option of using 7-keto in the formula as well.  Par's new product FL7 is pretty much a transdermal 7-keto inside of PH gel.  The problem is that the transdermal formula proposed above is intended for localized fat loss.  7-keto wouldn't take much effect inside of the sub-q layer.

    4. All of the ingredients proposed above have a high oral bioavailability.  We really wouldn't be achieving much through a transdermal of y-hcl,ua,caffeine, and forskolin besides the potential for localized fat loss. 

    5. In light of the new information, all the ingredients listed, Ua, caffeine,y-hcl,forskolin,and 7-keto would appear to be more effective at fat loss in an orally based product than over a transdermal.  The only ingredients that have perks transdermal are obviously the y-hcl, when used with a carrier that stays in the sub-q layer and the 7-keto when used in the formula that enters the bloodstream as it will reduce the release of cortisol I believe (explanation at http://www.1fast400.com/store/produc...roducts_id=485). 

    Just some stuff to consider...

    Thanks

    WYD
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    As far as that much stuff at once it won't be a big deal for your body to absorb it. BUT to put that much stuff in th bottle I would think that it won't all go into solution.. And Thats a problem.. I like the idea of y-hcl and caffine only. Very cheap and good for localized fat loss. The others can just be taken orally.. Hope that sheds a little light.. Talk to ya..
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    Hey Curt, now I need your help! How much caffeine would you add to a bottle of Lipoderm? I have some extra sitting around and mine as well try it out....
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    I was thinking around 100mg/day(Cause it won't be going into the blood stream).. You will have to figure out the math... Don't know much about dosages of the lipoderm.... Let me know if you can't figure it out.. Talk to ya... 
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    Originally posted by curt2go
    Don't know much about dosages of the lipoderm
    Just for reference purposes:

    Lipoderm-Y has a solubility of 25mg/ml (6g Y-hcl in 240ml bottle). 1.5 squirts = 1ml.

    Par's stated "max" dosage is 10 squirts 2x per day. Total application with 20 squirts per day would be 333.33mg of Y-hcl.
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    So is bdc or you curt going to make this mix available for use with y-hcl?   I am too lazy to make my own mixes.

     
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    If you are willing to test it. I have a bottle i wil send you . You have to get the Y for it but the rest i will give you. But you must keep VERY accuarate track of things. Let me know. I can have it out to you right away.. Talk to ya..
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    Originally posted by curt2go
    If you are willing to test it. I have a bottle i wil send you . You have to get the Y for it but the rest i will give you. But you must keep VERY accuarate track of things. Let me know. I can have it out to you right away.. Talk to ya..
     

    Y-HCL powder is available at 1fasts site if you wanna pick up a couple grams...

    peace

    WYD

     
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    Hey WYD do you want the brew? Talk to ya...
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    Originally posted by curt2go
    Hey WYD do you want the brew? Talk to ya...
     

    Definitely!  and if you could make two bottles, I'll have my girlfriend try it out as well.  I just need to purchase the powder.

     

    Thanks

    WYD

     
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    I will have to warn you its green. Iused colored aloe gel. I will wip up another batch and send then to you... We will work out details later.. Like address... Talk to ya..
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    Originally posted by curt2go
    I will have to warn you its green. Iused colored aloe gel. I will wip up another batch and send then to you... We will work out details later.. Like address... Talk to ya..
     

    LOL - Does it rub on green and stay like that? hahahah, people will think i have fungus growing off me!! Jk

     
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    No it rubs in awsome. It is mentholly for about 5 min as well. Talk to ya..
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    hey curt, i'd be willing to test it out, as well, if you wanted. but i was curious, what sort of bottle did you put the lotion in? i'm trying to think of a container that would be accurate for squirts.
    also...where are you getting your menthol from?
  

  
 

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