Ecdysterone Transdermal

[madruk]

How much ecdy powder would i need to put into penetrate and how many squirts would a need daily for it to be effective (ecdy powder from nutra at 94% potency)

 

[Rodja]

It won't work because the MW is too high to be absorbed through the skin.

 

[madruk]

awwwwwwwwww:whiner:...wahhhh

Anyway...someone said that its mw was close enough....so I am guessing they were wrong?

 

[Rodja]

Yes, they are wrong.

 

[Mixelflick]

Yes, they are wrong.

Generally speaking, you are correct. The most common ecdysterone used in sports-nutrition products is 20-hydroxyecdysone which has a molecular weight of 480.

Rubrosterone/3-epi-Rubrosterone however, has a much more manageable MW of 334, plenty small enough to pass with a good carrier. Certainly DMSO would carry it.

 

[madruk]

know where any is by any chance?

 

[Mixelflick]

know where any is by any chance?

I think it's in a new ALRI product, Pro-Anabol.

 

[ZIMM]

It won't work because the MW is too high to be absorbed through the skin.

does that go for methoxyisoflavone also?

this is what i found on methoxy mw
Changshu Fushilai Medicine & Chemical Co.,Ltd.

 

[stxnas]

It's molcecular formula is C17H14O3 ==> MW of ~266...

I'm not sure what this is or is supposed to do though.

 

[DeerDeer]

1: J Int Soc Sports Nutr. 2006 Dec 13;3:19-27. Links

Effects of methoxyisoflavone, ecdysterone, and sulfo-polysaccharide supplementation on training adaptations in resistance-trained males.Wilborn CD, Taylor LW, Campbell BI, Kerksick C, Rasmussen CJ, Greenwood M, Kreider RB.
Human Performance Lab, University of Mary Hardin Baylor, Belton, TX.

ABSTRACT : PURPOSE : Methoxyisoflavone (M), 20-hydroxyecdysone (E), and sulfo-polysaccharide (CSP3) have been marketed to athletes as dietary supplements that can increase strength and muscle mass during resistance-training. However, little is known about their potential ergogenic value. The purpose of this study was to determine whether these supplements affect training adaptations and/or markers of muscle anabolism/catabolism in resistance-trained athletes. METHODS : Forty-five resistance-trained males (20.5 +/- 3 yrs; 179 +/- 7 cm, 84 +/- 16 kg, 17.3 +/- 9% body fat) were matched according to FFM and randomly assigned to ingest in a double blind manner supplements containing either a placebo (P); 800 mg/day of M; 200 mg of E; or, 1,000 mg/day of CSP3 for 8-weeks during training. At 0, 4, and 8-weeks, subjects donated fasting blood samples and completed comprehensive muscular strength, muscular endurance, anaerobic capacity, and body composition analysis. Data were analyzed by repeated measures ANOVA. RESULTS : No significant differences (p > 0.05) were observed in training adaptations among groups in the variables FFM, percent body fat, bench press 1 RM, leg press 1 RM or sprint peak power. Anabolic/catabolic analysis revealed no significant differences among groups in active testosterone (AT), free testosterone (FT), cortisol, the AT to cortisol ratio, urea nitrogen, creatinine, the blood urea nitrogen to creatinine ratio. In addition, no significant differences were seen from pre to post supplementation and/or training in AT, FT, or cortisol. CONCLUSION : Results indicate that M, E, and CSP3 supplementation do not affect body composition or training adaptations nor do they influence the anabolic/catabolic hormone status or general markers of catabolism in resistance-trained males.

 

[ZIMM]

1: J Int Soc Sports Nutr. 2006 Dec 13;3:19-27. Links

Effects of methoxyisoflavone, ecdysterone, and sulfo-polysaccharide supplementation on training adaptations in resistance-trained males.Wilborn CD, Taylor LW, Campbell BI, Kerksick C, Rasmussen CJ, Greenwood M, Kreider RB.
Human Performance Lab, University of Mary Hardin Baylor, Belton, TX.

ABSTRACT : PURPOSE : Methoxyisoflavone (M), 20-hydroxyecdysone (E), and sulfo-polysaccharide (CSP3) have been marketed to athletes as dietary supplements that can increase strength and muscle mass during resistance-training. However, little is known about their potential ergogenic value. The purpose of this study was to determine whether these supplements affect training adaptations and/or markers of muscle anabolism/catabolism in resistance-trained athletes. METHODS : Forty-five resistance-trained males (20.5 +/- 3 yrs; 179 +/- 7 cm, 84 +/- 16 kg, 17.3 +/- 9% body fat) were matched according to FFM and randomly assigned to ingest in a double blind manner supplements containing either a placebo (P); 800 mg/day of M; 200 mg of E; or, 1,000 mg/day of CSP3 for 8-weeks during training. At 0, 4, and 8-weeks, subjects donated fasting blood samples and completed comprehensive muscular strength, muscular endurance, anaerobic capacity, and body composition analysis. Data were analyzed by repeated measures ANOVA. RESULTS : No significant differences (p > 0.05) were observed in training adaptations among groups in the variables FFM, percent body fat, bench press 1 RM, leg press 1 RM or sprint peak power. Anabolic/catabolic analysis revealed no significant differences among groups in active testosterone (AT), free testosterone (FT), cortisol, the AT to cortisol ratio, urea nitrogen, creatinine, the blood urea nitrogen to creatinine ratio. In addition, no significant differences were seen from pre to post supplementation and/or training in AT, FT, or cortisol. CONCLUSION : Results indicate that M, E, and CSP3 supplementation do not affect body composition or training adaptations nor do they influence the anabolic/catabolic hormone status or general markers of catabolism in resistance-trained males.

Not a good study since the methoxy dose is 800 mg and the ecedy is 200 mg . the avg dose that people report any results at all are 2 grams methoxy and 1 gram of ecedy daily.

The doses used in this study are the usual doses you here people saying it did nothing at all for them.

To bad they did not use high doses in a few athletes then maybe we could have put this thing to rest, at least the methoxy part!

 

[Rodja]

Not a good study since the methoxy dose is 800 mg and the ecedy is 200 mg . the avg dose that people report any results at all are 2 grams methoxy and 1 gram of ecedy daily.

The doses used in this study are the usual doses you here people saying it did nothing at all for them.

To bad they did not use high doses in a few athletes then maybe we could have put this thing to rest, at least the methoxy part!

It also does not state the timing of the doses.