Higenamine is not as potent as Ephedrine, but it is the most potent beta-agonist available as a dietary supplement. When used properly, especially in conjunction with other ingredients that work well with it like we have done in Alphamine and Norcodrene, it makes a big difference. Neuron doesn't like it because it has a short half life in rabbits. We were the first to release and test Higenamine in this industry, and I can tell you the effects of a proper Higenamine dose last a good while.
The short half life of some beta-agonists also allow more frequent and longer use, depending on how they are used. That is one reason why you see some people choosing ephedrine over clen.
Higenamine also differs from Ephedrine in that it does not cause the BP spike like ephedrine, and can actually induce NO. There is also nice human safety data behind Higenamine