USPlabs "Patented Anabolic" R&D -- Alpha Testing Q/A --

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    Quote Originally Posted by domore View Post

    If Coop buys, then I buy. If not, well, then I don't.
    3 caps a day.. we would need 6 bottles of versa-1 for an 8 week run...
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    Quote Originally Posted by mr.cooper69 View Post
    My thoughts on aegiline are in my final review of Versa-1, but the doses are key
    Good deal. I'll check it out.
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    Quote Originally Posted by mr.cooper69 View Post
    The existing data supports about an 800mg daily dose of aegeline
    Is this data human data? Because its octopamine metabolites are very weak b-3 agonists on human adipocytes.
    •   
       

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    Quote Originally Posted by kbayne View Post
    3 caps a day.. we would need 6 bottles of versa-1 for an 8 week run...
    Yeah, so much for the one cap-a-day.
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    Quote Originally Posted by domore View Post

    Yeah, so much for the one cap-a-day.
    Ya which sucks cause I was really looking forward to running two bottles for an 8 week run with prime and compound 20. Already gonna cost a pretty penny for 3 bottles of prime and 2 bottles of compound 20.
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    After all the evidence shown in beta-testers.....
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    Quote Originally Posted by Distilled Water View Post
    After all the evidence shown in beta-testers.....
    The response from the testers did seem very impressive.

    I just need to learn about the other ingredient (not CDP-Choline).
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    Quote Originally Posted by Distilled Water View Post
    After all the evidence shown in beta-testers.....
    Oh don't worry I'm still gonna stack versa-1 with prime and compound 20. Might run 2 caps a day though with versa-1.

    Reading all the logs got me very interested and excited about versa-1 and I still am

    And the IC deal is just too good to not get in on.

    Finally got it ordered. Thanks usp for this incredible deal!! I hope everyone gets in on it.
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    Quote Originally Posted by mr.cooper69 View Post
    USP, are you in the process of conducting more trials? The existing data supports about an 800mg daily dose of aegeline for most users (for significant b3-mediated activity), and CDP-Choline is best used at 500mg-1g daily. However, since this isn't a dedicated nootropic product, doses of ~300mg cdp-choline can provide nice health benefits and an increase in focus.

    Assuming 300mg aegeline and 100mg citocholine per cap, we're looking at about 3 caps daily for most users. Hence why I'm asking if there are some more trials being run of aegeline (which the IC release seemed to insinuate).

    Thanks!
    Isnt aegeline in the new version of oxyelite pro , guess I do not understand the big deal of this product .. Yet the alpha testers seemed to really like it..

    I did find this http://www.banlab.com/hearbs_details...hp?hear*****23

    Aegle marmelos (alkaloidal-amide, Aegeline 2) lowered blood glucose levels by 12.9% and 16.9% at 5 and 24h, respectively, in sucrose challenged streptozotocin induced diabetic rats model at the dose of 100mg/kg body weight. Aegeline 2 has also significantly decreased the plasma triglyceride (Tg) level by 55% (P<0.001), total cholesterol (TC) by 24% (P<0.05) and free fatty acids (FFA) by 24%, accompanied with increase in HDL-C by 28% and HDL-C/TC ratio by 66% in dyslipidemic hamster model at the dose of 50 mg/kg body weight. The compound 2 might be a beta(3)-AR agonist13.
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    Quote Originally Posted by lronFist View Post
    High Tower Pharmacology is publishing a blog about the ingredients in this product.
    When?
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    Quote Originally Posted by squatting View Post
    When?
    its up already
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    I have another question, does this affect hormones? IE as in a natty test booster. or is it just anabolic without any hormonal properties?
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    Quote Originally Posted by Jbrooks View Post
    Isnt aegeline in the new version of oxyelite pro , guess I do not understand the big deal of this product .. Yet the alpha testers seemed to really like it..

    I did find this http://www.banlab.com/hearbs_details...hp?hear*****23

    Aegle marmelos (alkaloidal-amide, Aegeline 2) lowered blood glucose levels by 12.9% and 16.9% at 5 and 24h, respectively, in sucrose challenged streptozotocin induced diabetic rats model at the dose of 100mg/kg body weight. Aegeline 2 has also significantly decreased the plasma triglyceride (Tg) level by 55% (P<0.001), total cholesterol (TC) by 24% (P<0.05) and free fatty acids (FFA) by 24%, accompanied with increase in HDL-C by 28% and HDL-C/TC ratio by 66% in dyslipidemic hamster model at the dose of 50 mg/kg body weight. The compound 2 might be a beta(3)-AR agonist13.
    The compound'seffects are dose/concentration dependent in terms of which molecular target itengages. As described in the USPlabs' patent, at a specified lower dose, thecompound possesses a thermogenic and cognitive effect, while at a much higher dose, thecompound possesses an anabolic effect.

    The anabolic amount makes subjects extremely hungry. You obviously don't want that in a Fat burner/appetite suppressant.

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    Quote Originally Posted by USPlabsRep View Post
    The compound'seffects are dose/concentration dependent in terms of which molecular target itengages. As described in the USPlabs' patent, at a specified lower dose, thecompound possesses a thermogenic and cognitive effect, while at a much higher dose, thecompound possesses an anabolic effect.

    The anabolic amount makes subjects extremely hungry. You obviously don't want that in a Fat burner/appetite suppressant.

    I've seen this exact phrase word for word on another board, that you? or is every usp rep been told to say that in regards to the questions regarding the ingredients?
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    Quote Originally Posted by rhizome View Post
    Is this data human data? Because its octopamine metabolites are very weak b-3 agonists on human adipocytes.
    I didn't even see the structure of the compound until recently. Do you have full text access to the rat data?

    If the primary metabolite is octopamine or an analogue, I will be very disappointed. Anecdotally, I got great pumps from the product, which I'm not even sure is a possible endpoint even if aegeline is metabolically active. I will never rule out placebo though, as I was not blinded.
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    Quote Originally Posted by thedarce View Post
    I've seen this exact phrase word for word on another board, that you? or is every usp rep been told to say that in regards to the questions regarding the ingredients?
    Correct, if asked the difference between OEP and VERSA-1 that is the companies answer..

    Darce is one of my favorite chokes.
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    Quote Originally Posted by USPlabsRep View Post
    Darce is one of my favorite chokes.
    mine too i always brabo/lapel choke everyone.
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    According to High Tower Pharmacology , aegeline MAY be inherently anabolic, however will probably not affect humans. Great.
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    Quote Originally Posted by AlexErdellan View Post
    According to High Tower Pharmacology , aegeline MAY be inherently anabolic, however will probably not affect humans. Great.
    Probably is a great word in science.
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    Quote Originally Posted by thedarce View Post
    mine too i always brabo/lapel choke everyone.
    Have to love the sneaky chokes....so quick.
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    Quote Originally Posted by mr.cooper69 View Post
    I didn't even see the structure of the compound until recently. Do you have full text access to the rat data?

    If the primary metabolite is octopamine or an analogue, I will be very disappointed. Anecdotally, I got great pumps from the product, which I'm not even sure is a possible endpoint even if aegeline is metabolically active. I will never rule out placebo though, as I was not blinded.
    200 or so placebo guys raving about it all month just like you did.
    100 percent money back.....although you will get more on eBay with this deal then if returned at the super low purchase price.
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    Quote Originally Posted by USPlabsRep View Post
    Probably is a great word in science.
    We'll see. I hope it works, I couldn't pass on the deal . Figured if I dont like it I can always sell the 2nd bottle on ebay for about 50 anyway.
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    Quote Originally Posted by USPlabsRep View Post
    200 or so placebo guys raving about it all month just like you did.
    100 percent money back.....although you will get more on eBay with this deal then if returned at the super low purchase price.
    I know you're confident in the product (otherwise why patent it?). Any strings attached with the guarantee? I'd like to try 3 caps/day
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    Quote Originally Posted by AlexErdellan View Post
    According to High Tower Pharmacology , aegeline MAY be inherently anabolic, however will probably not affect humans. Great.
    He said anabolic in adipose tissue lol. Cissus round 2!
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    Quote Originally Posted by mr.cooper69 View Post
    I know you're confident in the product (otherwise why patent it?). Any strings attached with the guarantee? I'd like to try 3 caps/day
    I will first say three caps is overkill. You are basing off data on glucose. We are not claiming that.

    With that said, all you have to do is return bottles with proof of purchase and your card will be instantly refunded without question.
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    Quote Originally Posted by AlexErdellan View Post
    We'll see. I hope it works, I couldn't pass on the deal . Figured if I dont like it I can always sell the 2nd bottle on ebay for about 50 anyway.
    You also receive a bottle of a month supply of agmatine500
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    With all the hype, why is everyone suddenly dubious now that Coop chimes in with a few doubts? Don't get me wrong, scepticism is a good thing in the supplement industry but no need to try make it out like USP is facilitating a huge scam, after all, a tonne of money would have been put into research/ development and patenting the product; none of which would be worthwhile if the product is too be doomed.

    I can't wait for it to drop on the planet; considering I cannot get the IC release here in NZ

    Edit: Not a shot at Coop, so don't hate on me
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    Quote Originally Posted by Jiigzz View Post
    With all the hype, why is everyone suddenly dubious now that Coop chimes in with a few doubts? Don't get me wrong, scepticism is a good thing in the supplement industry but no need to try make it out like USP is facilitating a huge scam, after all, a tonne of money would have been put into research/ development and patenting the product; none of which would be worthwhile if the product is too be doomed.

    I can't wait for it to drop on the planet; considering I cannot get the IC release here in NZ

    Edit: Not a shot at Coop, so don't hate on me
    I actually agree with this post 100%. I don't know enough about the product as there simply isn't a whole lot of data on aegeline. I think people should make their own educated decisions here.
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    I will vouch for this.. USPlabs ain't like other companies who depend on ads and other rubbish to push their products out just to get an upper hand.. We were given chances to test these products before release.. It was based on our feedback
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    Quote Originally Posted by Jiigzz View Post
    With all the hype, why is everyone suddenly dubious now that Coop chimes in with a few doubts? Don't get me wrong, scepticism is a good thing in the supplement industry but no need to try make it out like USP is facilitating a huge scam, after all, a tonne of money would have been put into research/ development and patenting the product; none of which would be worthwhile if the product is too be doomed.

    I can't wait for it to drop on the planet; considering I cannot get the IC release here in NZ

    Edit: Not a shot at Coop, so don't hate on me
    We will publish the animal studies (90 day study in Rats and Rabbits is not cheap) and in the middle of recruiting subjects for a study at Memphis. before release, we conducted a pilot study on safety markers (as discussed in the write up).

    Companies search available (as we do) to develop a product, but in this case, we are creating the research. There are pros and cons to it.

    Pro- we are the first and with the patent, we can liscense it out..
    Cons- Innovation doesn't come without attacks from the competition....it's the nature of the industry.
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    I used the product and loved it, so i bought the IC release.

    While the anabolic in adipose tissue confuses me i know i was cutting and never saw signs of impaired fatloss.
    E-Pharm Rep... PM me with any questions or concerns
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    Quote Originally Posted by 3clipseGT View Post
    I used the product and loved it, so i bought the IC release.
    Same here.
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    Quote Originally Posted by 3clipseGT View Post
    I used the product and loved it, so i bought the IC release.

    While the anabolic in adipose tissue confuses me i know i was cutting and never saw signs of impaired fatloss.
    The competition will manipulate data to serve there purposes...
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    Quote Originally Posted by freezito View Post
    Same here, hit the link seconds after recieving and nothing and nothing since. This is quite disapointing since its been hyped in our heads for months. Its like waking up christmas morning to only find out that your house was robbed and all the presents stolen
    Lulz, wowzers... I wasn't that hurt, just thought the logical thing to do is extend the timeframe considering the down time... uspl will make sure everyone gets a chance to take advantage of it, I'm sure.

    I was dying to read that write up more then anything... still need to go in depth now and check the referenced studies. I just like to know how things work, there is one thing I already know though, it DOES work.

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    Quote Originally Posted by Distilled Water View Post
    After all the evidence shown in beta-testers.....
    exactly.

    I doubt that you can guess what the dose per cap really is, look at minimal human data and then come to an absolute conclusion on how much versa-1 needs to be taken. The largest example of what it can actually do ever needed, real world detailed use, is available to us in abundance.

    I would like to see myself what a double dose on workout days would bring(morning w/cardio, evening w/ weight dosing) , but even without doing that I know I'll get good results from taking it as suggested...

    The one thing I REALLY would like to know is what mechanism is behind the ravenous hunger that was created by taking versa-1. It was insane, and considerably more so impressive about it was I was taking copious amounts of stimulants/fat burners each day alongside which normally destroy my appetite.

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    Quote Originally Posted by mr.cooper69 View Post
    I didn't even see the structure of the compound until recently. Do you have full text access to the rat data?

    If the primary metabolite is octopamine or an analogue, I will be very disappointed. Anecdotally, I got great pumps from the product, which I'm not even sure is a possible endpoint even if aegeline is metabolically active. I will never rule out placebo though, as I was not blinded.
    wonder if there was some shake-n-bake agmatine in the beta testers supplements (ironic the IC release includes it given the pump people are saying they get)
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    Quote Originally Posted by lronFist View Post

    Not really. The placebo effect can dupe anyone, especially if it is trumped up with exceptional marketing.
    I think if it was placebo one of the many guys that are incredibly in tune with what their body can do and how it reacts to most supplementation would have called farce. And there was absolutely no marketing to be had or tip offs to testers of what possible effects may be, the effects came with great proof and were individually reported.

    I've personally been lifting and extensively supplementing for over 11 years now and know what's working for me and what's not. I offered an honest 30 day detailed log of my experience and the results achieved and considering all the variables(namely that I was cutting) the results are quite impressive. I didn't even view a single fellow testers log for 2 weeks as a personal way of avoiding any suggested effects turning into placebo... going back and reading my experience was identical to theirs... Just no way placebo effected my weight and body composition like this in 30 days and didn't get a single bad review of over 60 testers... placebo isn't so powerful as to effect that many testers physiologically during simultaneous testing.

    There are plenty of other guys even more so at their peak then myself that still saw noticeable results as well....

    Bottom line is, the stuff works right now, as is, at the dose suggested, and all that is left is to prove HOW it works... you can wait around for that data to present itself if you like before taking this, no skin off my back. Just don't call me and 59 others liars in the meantime, thank you.

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    Quote Originally Posted by lronFist View Post

    You are very confused. The placebo effect is not malingering or "lying," it is completely unintentional. Anyone is susceptible to its effects.
    Someone here is confused, Sir, and it is not I.

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    Quote Originally Posted by lronFist View Post
    Anyone is susceptible to its effects.
    Anyone and everyone are two completely different things.

    I'm telling you what I personally experience and giving detailed quantifiable data based off my experience, progress and feelings across a 30 day period, the first half of which I had zero outside influence on my observations.

    Placebo cannot create these type of effects to this extent, it has its limits. It also will not effect outright so many individuals simultaneously.

    If you are saying the results of my experience are placebo and I'm telling you they aren't, then you sir, are calling me a liar.

    Quit turning this into a debate over the meaning of placebo.

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    Quote Originally Posted by lronFist View Post

    You seem quite hostile.
    Tone and emphasis are completely lost through conversing via text my friend.

    Defensive I may be of my stance, but hostility there is none.

    You seem to be quite good at deflecting yourself though, as you seen unable to provide any sort of defense to your own stance when mine is the opinion of many.

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