You asked for it. Now its here. Oral Sustain Alpha Liqua-Vade!
- 10-26-2009, 09:53 PM
- 10-26-2009, 10:32 PM
I wouldn't consider undertaking a biz opportunity with such a small potential market, and it's outside of my line of work as a CDS/variance-swap dealer. One of my points is that PP is missing an opportunity in pricing it outside the EOD.
10-26-2009, 11:26 PM
Also, if you have uncertainty about a low concentration of HPMC inhibiting precipitation and crystallization of active compounds, I suggest you read this study -
Development of supersaturatable self-emulsifying drug delivery system formulations for improving the oral absorption of poorly soluble drugs.
Gao P, et al.
Expert Opin Drug Deliv. 2006 Jan;3(1):97-110
FYI, 0.25mg/ml was sufficient to maintain a supersaturated state in a SEDDS.
Home office? Nope.. thats actually me in the avatar pulling out a batch of red chinese ginseng from our edenlabs coldfinger extractor in our 5k sq ft production facility.. nothing too special... but not a home office by any means.
10-27-2009, 03:31 AM
Wow Eric, very well thought out responses and presented without the attacks sprinkled in. Speaks volumes about your character AND your company. Open minds disagree, closed minds disregard. All too often on these forums people attack products without knowing enough about them LOL.
I already got my Sustain earlier today. Other than a slight aftertaste of soap lol, I absolutely prefer this than the topical. Three seconds and I'm good to go. Topical takes too long to dry as I'm always in a rush out the door.
Oh, and thanks again for the XXL t-shirt w/ my order. Fits good!
10-27-2009, 12:13 PM
Sirtis doesn't use a SEDDS, and achieved much higher plasma concentrations then the journal-data you provide. You have no empirical data that you haven't pulled from the web.
Buccal absorption with micronized resveratrol. Yeah, it makes a difference.
You market a topical resveratrol supplement when the data is universally in agreement that you cannot achieve a detectable, let alone a therapeutic plasma conc. with topical resveratrol. Yet you continue to market the bullsh*t.
Last edited by riskarb; 10-27-2009 at 02:49 PM.
10-27-2009, 12:20 PM
Sirtis uses micronized resveratrol in its SRT501 compound. Also, I am sure you've seen the Westphal data:
500mg/kg micronized resveratrol, no carrier
400mg/kg micronized resveratrol, DOSS+HPMC
A > 2x plasma conc. on micronized over standard particle size. A 4x increase in HPMC/DOSS.
10-27-2009, 03:09 PM
I'll concede that I probably know as much about SEDDS as you know about what is best-practice replication for a Nikkei 10k-strike exotic lookback call option (my line of work). I have no interest in being schooled on SEDDS. I am commenting on the use of micronized for buccal absorption. Regardless, the Westphal data (aforementioned graph) shows the superiority of micronized resveratrol over standard particle size. The goal is to avoid conjugation, and the AUC is better with micronized. We've witnessed the death of your argument made by your "granulated sugar" analogy.
10-27-2009, 05:48 PM
What was the relevance of this post anyway? Are you mixing dioctyl (2-ethylhexyl) sulfosuccinate and HPMC into a home resveratrol concoction or something? This may be fun for the imminst crowd but not everybody feels safe with home tinkering just to save a buck...
10-27-2009, 06:29 PM
10-28-2009, 06:12 PM
10-29-2009, 01:50 PM
I am not a medical Dr, please keep in mind that this answer is for information purposes only, and is not intended to diagnose, treat or replace sound medical advice from your physician or health care provider.
10-29-2009, 02:15 PM
It is a mild AI though, so if you need serious E2 control your better off going with something stronger. SA isnt going to keep estrogen in range if you're doing 500mg/week test.
10-30-2009, 02:52 PM
Will the oral be available soon in the TRS combo? Also, since the booting of 1-t tren (RIP), does PP have any plans for anything new along those lines?
10-30-2009, 03:00 PM
10-30-2009, 08:48 PM
11-01-2009, 07:46 PM
I was going to make this point. Resveratrol specialists/enthusiasts think that micronized loaded with tween is the way to go. It is extremely expensive however, not the tween bit but grinding it to incredibly small particles.
PP has had the charge against it that TD never got past the skin fat - something like that. This is a step to address that criticism.
The guy that will know is Knowbull: if he did a sponsored log whatever the outcome of that is would be really meaningful.
11-01-2009, 08:07 PM
I've not followed the thread the whole way through. The background is that the current thinking is resveratrol is best micronized and delivered in tween-80, at least that was the last time I followed it (about 4 months). Clearly PP hasn't micronized - it is a very expensive process. Eric here argues there is no need if the organic (chemistry) delivery system if its perfectly dissolved:
PP certainly have an interesting product, but as posted above it needs a heavy duty user into top-grade resveratrol to try it. At a guess it looks like by super-saturating then you avoid it dropping out of solution whilst it is adsorbing against the alimentary tract.
11-02-2009, 12:29 AM
11-02-2009, 10:17 AM
i just finished using the TRS, Prime, low dose clomid(25mg MWF) and ldex(.25mg E4D) for my initial 4 week hardcore pct. I have 8 more weeks of otc pct lined out. Then bloodwork mid January.
My cycle was 16 weeks, started using the transdermal SA(3 on 3 off) after 8weeks in.
I have dropped about 5-6(Gained about 25#'s,185-210 actually) pounds since pct started and some strength.....But what totally amazes me, i have lost no sexual performance or libido.
I cannot honestly pinpoint what is working and what isnt, but i know for certain.>>>>
TRS will continue to be a staple in any pct that i run.
I have 4 TRS units on hand. Not all for me, but when my bros come for pct, i hook them up.
My 2 pennies.
11-02-2009, 03:01 PM
11-02-2009, 05:03 PM
11-03-2009, 05:42 PM
11-04-2009, 02:00 AM
In about 2 weeks, I will be starting a natty test boosting/AI stack (haven't done so in awhile, in need of it).. The stack will consist of Mass FX/TD Formestane and HGHup.. How overkill would it be to throw liquid sustain alpha into the mix?! LOL
11-04-2009, 03:40 AM
Well this new delivery system seems to be working for me, morning glories are up...i also feel that this seems more potent from my general senses. Day 5 of running it in the TRS combination.
Also i highly recommend the worm in water method. Slides down you throat that way. The straight shot method is harsh...
11-04-2009, 12:36 PM
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