Baclofen and GABA-A

[bigironkiller]

does anyone have any insights to the use of Baclofen and/or GABA-A for TRT. From what ive read, Baclofen inhibits the negative testosterone feedback loop, increase LH/FSH, GH/IGF. here are a few studies,:

1) GABA Control of GnRH Release from the Ewe Hypothal...[Reprod Domest Anim. 2008] - PubMed Result

2) GABA Control of GnRH Release from the Ewe Hypothal...[Reprod Domest Anim. 2008] - PubMed Result

3) GABA Control of GnRH Release from the Ewe Hypothal...[Reprod Domest Anim. 2008] - PubMed Result

 

[bigironkiller]

anyone??

 

[smc252]

Very interesting, I have never heard this...

 

[cpeil2]

does anyone have any insights to the use of Baclofen and/or GABA-A for TRT. From what ive read, Baclofen inhibits the negative testosterone feedback loop, increase LH/FSH, GH/IGF. here are a few studies,:

1) GABA Control of GnRH Release from the Ewe Hypothal...[Reprod Domest Anim. 2008] - PubMed Result

2) GABA Control of GnRH Release from the Ewe Hypothal...[Reprod Domest Anim. 2008] - PubMed Result

3) GABA Control of GnRH Release from the Ewe Hypothal...[Reprod Domest Anim. 2008] - PubMed Result

Baclofen has been discussed a little on Meso. A key word search would probably turn up the threads.

 

[EasyEJL]

hmm where do I find GABA-A? or how do I tell what amount in gaba is a vs b?

 

[bigironkiller]

yeah, i found the meso site after i posted this, but didnt finish reading the whole thread b/c its ten pages long. i emailed the original poster to ask what results he got, but no response yet.

 

[jinxie]

yeah, i found the meso site after i posted this, but didnt finish reading the whole thread b/c its ten pages long. i emailed the original poster to ask what results he got, but no response yet.

I read the thread, and dont recall anything notably positive. A guy named Fred was strident that it did nothing whatsoever for T levels. And another guy taking it for MS had nothing positive to say. It sounds like a pipe dream.

 

[krazy]

I know Baclofen is supposed to be alot like Phenibut and Phenibut builds a super rapid tolerance. Something to keep in mind...

 

[chemiuser]

I'm sure there are safer and better approaches

 

[Cgkone]

does anyone have any insights to the use of Baclofen and/or GABA-A for TRT. From what ive read, Baclofen inhibits the negative testosterone feedback loop, increase LH/FSH, GH/IGF. here are a few studies,:

1) GABA Control of GnRH Release from the Ewe Hypothal...[Reprod Domest Anim. 2008] - PubMed Result

2) GABA Control of GnRH Release from the Ewe Hypothal...[Reprod Domest Anim. 2008] - PubMed Result

3) GABA Control of GnRH Release from the Ewe Hypothal...[Reprod Domest Anim. 2008] - PubMed Result

Wow
Interesting
I take gaba almost daily.
Energy pain, relief, anti depressant.
Combined with bacalafen I get more high feeling.
Talkative.
Gaba makes my cardio a blast.
I find that not everybody responds to it.
But the ones that do and find there dose they love it.
Very interesting stuff you linked.
Thanks

 

[chemiuser]

baclofen doesn't work on GABA-A receptors it's a GABA-B agonist. Benzos are gaba-a.

 

[Cgkone]

I lo f