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    Definitely interested in this being that i am in the military and we run atleast 3x a week. So ill be picking some up once its out!
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    Quote Originally Posted by 3clipseGT View Post
    Definitely interested in this being that i am in the military and we run atleast 3x a week. So ill be picking some up once its out!
    It's right around the corner. We would love to hear your feedback, especially in a military context!
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    What a tease
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    Quote Originally Posted by xhrr View Post
    What a tease
    You been talking to my wife?
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    These two studies go together...do we want to play the "How"? game?

    J Appl Physiol (1985). 2010 Dec;109(6):1653-61. doi: 10.1152/japplphysiol.00598.2010. Epub 2010 Sep 16.
    Endurance training-induced accumulation of muscle triglycerides is coupled to upregulation of stearoyl-CoA desaturase 1.
    Dobrzyn P, Pyrkowska A, Jazurek M, Szymanski K, Langfort J, Dobrzyn A.
    Source

    Laboratory of Cell Signaling and Metabolic Disorders, Nencki Institute of Experimental Biology, 3 Pasteur St., 02-093 Warsaw, Poland. adobrzyn@nencki.gov.pl
    Abstract

    Stearoyl-CoA desaturase (SCD), a rate-limiting enzyme in the biosynthesis of monounsaturated fatty acids, has recently been shown to be a critical control point in regulation of liver and skeletal muscle metabolism. Herein, we demonstrate that endurance training significantly increases both SCD1 mRNA and protein levels in the soleus muscle, whereas it does not affect SCD1 expression in the EDL muscle and liver. Desaturation index (18:1Δ9/18:0 ratio), an indirect indicator of SCD1 activity, was also significantly higher (3.6-fold) in soleus of trained rats compared with untrained animals. Consistent with greater SCD1 expression/activity, the contents of free fatty acids, diacylglycerol, and triglyceride were elevated in soleus of trained rats. However, training did not affect lipid concentration in EDL and liver. Additionally, endurance training activated the AMP-activated protein kinase pathway as well as increased peroxisome proliferator-activated receptor (PPAR)-δ and PPARα gene expression and activity in soleus and liver. Increased lipid accumulation in soleus was coupled with elevated protein levels of fatty acid synthase, mRNA levels of diacylglycerol acyltransferase and glycerol-3-phosphate transferase, as well as increased levels of proteins involved in fatty acid transport (fatty acid translocase/CD36, fatty acid transport protein 1). Interestingly, sterol regulatory element-binding protein (SREBP)-1c expression and SREBP-1 protein levels were not affected by exercise training. Together, the obtained data suggest that SCD1 upregulation plays an important role in adaptation of oxidative muscle to endurance training.

    PMID:
    20847127
    [PubMed - indexed for MEDLINE]

    PLoS One. 2012;7(3):e33815. doi: 10.1371/journal.pone.0033815. Epub 2012 Mar 27.
    An ethanol extract of Artemisia iwayomogi activates PPARδ leading to activation of fatty acid oxidation in skeletal muscle.
    Cho SY, Jeong HW, Sohn JH, Seo DB, Kim WG, Lee SJ.
    Source

    Health Science Research Institute, Research and Development Center, AmorePacific Corporation, Bora-dong, Giheung-gu, Yongin-si, Korea.
    Abstract

    Although Artemisia iwayomogi (AI) has been shown to improve the lipid metabolism, its mode of action is poorly understood. In this study, a 95% ethanol extract of AI (95EEAI) was identified as a potent ligand of peroxisome proliferator-activated receptorδ (PPARδ) using ligand binding analysis and cell-based reporter assay. In cultured primary human skeletal muscle cells, treatment of 95EEAI increased expression of two important PPARδ-regulated genes, carnitine palmitoyl-transferase-1 (CPT1) and pyruvate dehydrogenase kinase isozyme 4 (PDK4), and several genes acting in lipid efflux and energy expenditure. Furthermore, 95EEAI stimulated fatty acid oxidation in a PPARδ-dependent manner. High-fat diet-induced obese mice model further indicated that administration of 95EEAI attenuated diet-induced obesity through the activation of fatty acid oxidation in skeletal muscle. These results suggest that a 95% ethanol extract of AI may have a role as a new functional food material for the prevention and/or treatment of hyperlipidermia and obesity.

    PMID:
    22479450
    [PubMed - indexed for MEDLINE]
    PMCID:
    PMC3313949
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    No one out sciences our label!
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    Quote Originally Posted by dsade View Post
    You been talking to my wife?
    She said I had to tighten up first with some CardioTryx and HIIT :/ feels bruh
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    Will this be coming out next week (mid-October) hopefully please pretty please?

    Slightly related, I do fasted state cardio for an hour every morning, and I'm on a keto diet. It's pretty hard for me to stay down at 50-60% VO2 max for "optimal fat burn," as my heart rate wants to go higher. Is it a bad idea to go above that range if i'm not carbing up, and want to burn as much fat as possible during that hour? Would I just burn more ketones, or would I start eating up muscle?

    Anything in CardioTryx that would help ?
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    Quote Originally Posted by vasu View Post
    Will this be coming out next week (mid-October) hopefully please pretty please?

    Slightly related, I do fasted state cardio for an hour every morning, and I'm on a keto diet. It's pretty hard for me to stay down at 50-60% VO2 max for "optimal fat burn," as my heart rate wants to go higher. Is it a bad idea to go above that range if i'm not carbing up, and want to burn as much fat as possible during that hour? Would I just burn more ketones, or would I start eating up muscle?

    Anything in CardioTryx that would help ?
    you should stop worrying about staying in fat burning/V02 ranges and do sprints or HIIT
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    Quote Originally Posted by vasu View Post
    Will this be coming out next week (mid-October) hopefully please pretty please?

    Slightly related, I do fasted state cardio for an hour every morning, and I'm on a keto diet. It's pretty hard for me to stay down at 50-60% VO2 max for "optimal fat burn," as my heart rate wants to go higher. Is it a bad idea to go above that range if i'm not carbing up, and want to burn as much fat as possible during that hour? Would I just burn more ketones, or would I start eating up muscle?

    Anything in CardioTryx that would help ?
    This'll probably hit around the 24th, but yeah don't stress about the mythical fat burning zone. Go balls out with intervals.
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    Quote Originally Posted by dsade View Post
    This'll probably hit around the 24th, but yeah don't stress about the mythical fat burning zone. Go balls out with intervals.
    I can 't wait to see what fills that white on the label. This will go great with my Sleephoria.
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    Quote Originally Posted by dsade View Post
    This'll probably hit around the 24th, but yeah don't stress about the mythical fat burning zone. Go balls out with intervals.
    I wish I could do HIIT, but some old knee and foot injuries prevent this
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    Quote Originally Posted by vasu View Post
    I wish I could do HIIT, but some old knee and foot injuries prevent this
    Have access to a rower?
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    Quote Originally Posted by xhrr View Post
    Have access to a rower?
    Nope, but I was thinking about getting one in the future. All I have at home is an elliptical
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    Right on schedule!
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    Quote Originally Posted by dsade View Post
    <img src="http://anabolicminds.com/forum/attachment.php?attachmentid=89 951"/> Right on schedule!
    Since it's coming out on my birthday can u tell me where to purchase it before the public
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    Is the 24th when it hits nutraplanet/predator nutrition?
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    Should hit Nutra by the 24th, and Predator a week later
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    How would this work with abliderate ammo on a low to no carb diet? I just picked up ammo from NP and was thinking about logging it but had my eye on this for a while.
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    Quote Originally Posted by zb126 View Post
    How would this work with abliderate ammo on a low to no carb diet? I just picked up ammo from NP and was thinking about logging it but had my eye on this for a while.
    How much and what type of Cardio are you planning? What are your goals?
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    Quote Originally Posted by dsade View Post
    How much and what type of Cardio are you planning? What are your goals?
    I've been doing interval training, probably would continue with that and do a longer run on the weekends. Been doing full body circuit training, and intervals / cardio after. Goal is to recomp, and cut bodyfat particularly around the midsection.
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    Quote Originally Posted by zb126 View Post
    I've been doing interval training, probably would continue with that and do a longer run on the weekends. Been doing full body circuit training, and intervals / cardio after. Goal is to recomp, and cut bodyfat particularly around the midsection.
    Sounds like this would be perfect for you.
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    Quote Originally Posted by dsade View Post
    Sounds like this would be perfect for you.
    forgot to specify how much -- usually around 25-30 minutes of 1:30 on 1:00 walking. Is that enough? I figured ammo would be a good addition for cortisol but wasn't sure if thats enough cardio for cardiotryx
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    Quote Originally Posted by zb126 View Post
    forgot to specify how much -- usually around 25-30 minutes of 1:30 on 1:00 walking. Is that enough? I figured ammo would be a good addition for cortisol but wasn't sure if thats enough cardio for cardiotryx
    If you are going balls out for your 1:30 (that was assumed since any other interval would be a waste) then that will be plenty.
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    Quote Originally Posted by dsade View Post
    If you are going balls out for your 1:30 (that was assumed since any other interval would be a waste) then that will be plenty.
    Well I do skip for the first thirty seconds... hahaha
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    Quote Originally Posted by zb126 View Post
    Well I do skip for the first thirty seconds... hahaha
    As long as you keep repeating "Cinderella dressed in Yellow" then you are still hardcore.
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    Update ?
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    Scheduled for release around the 28th or 29th.
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    Will prob b doing an ammo cardiotryx stack. Will this still have that rhodiola extract u mentioned?
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    When will the write up be released
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    Quote Originally Posted by fcbarca12 View Post
    When will the write up be released
    Soon...
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    Rhodiola crenulata?
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    Quote Originally Posted by phantom View Post
    Rhodiola crenulata?
    Crenulata/Rosea blend.
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    Sounds very intersting. Crenulata extract has some good reads on it
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    Quote Originally Posted by dsade View Post
    Scheduled for release around the 28th or 29th.
    4-5 days left!
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    Bump
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    Quote Originally Posted by phantom View Post
    Bump
    Full label, with ingredients, is posted on Facebook.

    We had a slight hiccup with production, so we hit a delay. I will know more on Monday.
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    Just saw. Very cool. Gna need to do some reading on extracts lol Hopefully the delay wnt be long
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    Do you see this being useful for 2 a day workouts (lifting) as opposed to just cardio?
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