Augmatine

[Ev52]

In NA-rala 300mg has 60mg of salt leaving 240mg of r-lipoic acid

[dinoiii]

what did you think use Agmatine on low carb diet?

I like it?!? (unsure what more you are seeking with this)

What are your thoughts on someone using this who is also taking BP meds, is there a chance of it could drive a person Hypotensive ????

I suppose in a hypothetical case...perhaps, but autoregulation of the vasculature likely won't allow someone to go significantly hypotensive; and I haven't heard of anything in almost 5 years of use with the compound in various individuals. What Rx are you taking - if you don't mind me asking?



D_

[AutoKal47]

Originally Posted by MAxximal
what did you think use Agmatine on low carb diet?

I like it?!? (unsure what more you are seeking with this)

D_

What about dosing/timing when in low carb doc?

[RipdnTxs]

I take Telmisartan, 80 mg and Atenol 12.5 mg daily...

[dinoiii]

I take Telmisartan, 80 mg and Atenol 12.5 mg daily...

Well, I am unaware of interactions with ARBs or Beta-Blockers, although I am not necessarily a fan of atenolol in the first place:
When compared to placebo for the treatment of hypertension (4 trials with about 3,000 patients total), there was no benefit for atenolol in terms of mortality, cardiovascular mortality or MI. There was a benefit for stroke, but this was mainly from one trial in which atenolol was not used as monotherapy in most patients.

In 3 trials with about 7,000 patients that compared atenolol to other anti-hypertensives, atenolol fared worse than the other medications for all parameters except for MI, where it was about the same.

The authors speculate that the non-lipophilic nature of atenolol (unlike metoprolol and others) might play a role, as might a lesser or absent influence on LVH, compared with other medications. They note that there have been no good trials comparing different beta-blockers in hypertension, thus this need not apply to other beta-blockers. And, of course, beta-blockers have an important role to play in the setting of ischemic heart disease, CHF and arrhythmias.

I’m not a big fan of meta-analyses, in general, but this one is intriguing, and does make atenolol seem much less attractive for hypertension (and perhaps for other indications as well).

Alas, discussion of your anti-hypertensives was not necessarily the question; BUT I still cringe at the use of this particular agent.


D_

[dinoiii]

Originally Posted by MAxximal
what did you think use Agmatine on low carb diet?


What about dosing/timing when in low carb doc?

I don't think it changes much from when not on a low carb diet and as suggested in discussions before this (probably single-best time to take it is first thing in AM and every 24 hours thereafter); you are talking about an acting insulinomimetic, however, so it may potentiate symptoms of hypoglycemia in that setting. This would be a challenge in the normal population at large given the auto-regulatory set-up that inherently drives blood sugars in a neat range of 70-100 (+/- 5) mg/dl.

D_

[RipdnTxs]

I was given the Atenolol for my heart rate, sometimes in the past just rolling over in bed would cause my heart rate too increase alot for about a minute or so and then come back down. The BP med is doing a good job of keeping my BP at a normal level, I,m actually going to ask my Cardiologist if I can stop and see if I even need it, some days I forget to take it and have no issues with racing heat rate, when prescribed this med., I was under a great deal of stress in my personal life and I feel this had alot to do with the heart rate issue. I really appreciate you commenting on this, I will give this supplement a try soon and see how it goes.......





[UOTE=dinoiii;3086962]Well, I am unaware of interactions with ARBs or Beta-Blockers, although I am not necessarily a fan of atenolol in the first place:
When compared to placebo for the treatment of hypertension (4 trials with about 3,000 patients total), there was no benefit for atenolol in terms of mortality, cardiovascular mortality or MI. There was a benefit for stroke, but this was mainly from one trial in which atenolol was not used as monotherapy in most patients.

In 3 trials with about 7,000 patients that compared atenolol to other anti-hypertensives, atenolol fared worse than the other medications for all parameters except for MI, where it was about the same.

The authors speculate that the non-lipophilic nature of atenolol (unlike metoprolol and others) might play a role, as might a lesser or absent influence on LVH, compared with other medications. They note that there have been no good trials comparing different beta-blockers in hypertension, thus this need not apply to other beta-blockers. And, of course, beta-blockers have an important role to play in the setting of ischemic heart disease, CHF and arrhythmias.

I’m not a big fan of meta-analyses, in general, but this one is intriguing, and does make atenolol seem much less attractive for hypertension (and perhaps for other indications as well).

Alas, discussion of your anti-hypertensives was not necessarily the question; BUT I still cringe at the use of this particular agent.


D_[/QUOTE]

[BBB]

I've purchased bulk agmatine from Nutra. I'm going to take 750 mg/day for several months and see what transpires. Having said that, I'm really not sure what to expect. Some say better pumps, others recomp and still others better overall health. This I can say, the stuff is bitter as sin.

[AutoKal47]

I don't think it changes much from when not on a low carb diet and as suggested in discussions before this (probably single-best time to take it is first thing in AM and every 24 hours thereafter); you are talking about an acting insulinomimetic, however, so it may potentiate symptoms of hypoglycemia in that setting. This would be a challenge in the normal population at large given the auto-regulatory set-up that inherently drives blood sugars in a neat range of 70-100 (+/- 5) mg/dl.

D_

Thanks doc I got no problem with hypo, lol I go hypo 5 times a week usually

[dinoiii]

I've purchased bulk agmatine from Nutra. I'm going to take 750 mg/day for several months and see what transpires. Having said that, I'm really not sure what to expect. Some say better pumps, others recomp and still others better overall health. This I can say, the stuff is bitter as sin.

Bites nails in anticipation. I hope your experiment goes well. I have dosed it up as high as 4-5 grams for 3 months at a time without a lot of "consequence" so another thing I could likely say is toxicity is probably exceedingly low; so why not.

Thanks doc I got no problem with hypo, lol I go hypo 5 times a week usually

Concurrent insulin use?


D_

[MAxximal]

I don't think it changes much from when not on a low carb diet and as suggested in discussions before this (probably single-best time to take it is first thing in AM and every 24 hours thereafter); you are talking about an acting insulinomimetic, however, so it may potentiate symptoms of hypoglycemia in that setting. This would be a challenge in the normal population at large given the auto-regulatory set-up that inherently drives blood sugars in a neat range of 70-100 (+/- 5) mg/dl.

D_

so if i consume 1g on AM this will NOT kick me out of Ketosis?

[AutoKal47]

Concurrent insulin use?

D_

Oh not at all, I'm 100% natural (altho' I don't know if insulin use would be
considered not natty..), from starvation I guess

[T-Bone]

Bites nails in anticipation. I hope your experiment goes well. I have dosed it up as high as 4-5 grams for 3 months at a time without a lot of "consequence" so another thing I could likely say is toxicity is probably exceedingly low; so why not.






Concurrent insulin use?


D_

Is there really any additional benefit by going over 1 gram per day?. At 1 gram per day the price is reasonable, but definitely not at 4-5.

[Sourdough]

I've purchased bulk agmatine from Nutra. I'm going to take 750 mg/day for several months and see what transpires. Having said that, I'm really not sure what to expect. Some say better pumps, others recomp and still others better overall health. This I can say, the stuff is bitter as sin.

interested in your results... Ive heard nothing but good things about the production versions out but have hardly heard anything about the bulks and I usually try to get my supps in bulk that I know are going to be legit as I can get anyhow...

[AutoKal47]

interested in your results... Ive heard nothing but good things about the production versions out but have hardly heard anything about the bulks and I usually try to get my supps in bulk that I know are going to be legit as I can get anyhow...

I got bulk too, I should get it in a coupla days

[bigdavid]

Oh not at all, I'm 100% natural (altho' I don't know if insulin use would be
considered not natty..), from starvation I guess

Might not be considered natural but there is no way someone could test for it from my understanding

[Sourdough]

I got bulk too, I should get it in a coupla days

nice man id be interested in following along your results.. if your not going to be running any kinda log then at least hit me up after your a lil way into it to lmk if your seeing the desired and mentioned effects

[AutoKal47]

nice man id be interested in following along your results.. if your not going to be running any kinda log then at least hit me up after your a lil way into it to lmk if your seeing the desired and mentioned effects

I just started the Swole Stack log, and I have another sponsored log to fill after that one ugh..

But I will definitely try Agmatine while on the Swole and add in there or just make a review of it in here.
Worse case scenario count on it, I'll hit you up and let you know, I'm also very interested in how it'll work,
got a hefty 50gr tub too, so it'll last enough for a long-ish term use report

[Sourdough]

niiiiiiice.

[MAxximal]

i used with food but this time i thinking taking without.