I just started a few weeks ago. I've read that it can take up to 6 months before the benefits are noticed. I've been disappointed by Bacopa but I haven't given up. I've just about been able to do without coffee which I think has done some damage to my nerves and memory. I drank strong tall cups of Peets and Starbucks everyday for years and years and followed up with second cups of coffee or diet coke.