Ani should always be taken with some healthy fats anyways. I take mine with Krill Oil caps if I can't take it with a meal because of it's quick absorption. Ani also has an anxiolytic component to it as well not evidenced in the likes of Piracetam or Prami. It does stack decent, in my experience with 10mgs Noopept but I rarely take it first thing in the morning. Normally, I'd dose it at 1500-1600mgs with some fish oils or a meal and that's about it for the day. I'll cycle on and off various noots every few months. If you haven't tried 500mgs of a dopamine precursor like L-Phen/ or acetyl l-tyrosine + 450mgs artichoke extract and 10mgs coleus forskolii, it's relatively cheap and I, like others, have had significant results with it in terms of focus, alertness, cognition and overall mood. Google Long Term Potentiation and Artichoke Extract and it should take you to some info on this stack...gaining quite the popularity even by longtime noot users. I picked it up just based on user experiences and because it was cheap. Already had the dopamine precursor anyways. Worth the money and I'm on day 8 or 9, used first thing in the morning with my medium coffee. Nice effect.