YOUR favorite GDA? recommend me something :D

[pyrobatt]

maybe because theres lots of evidence of it causing cancer? ive seen companies talk about staying away from it, then proceed to sell it simply because people want it anyways. lol

considering you can easily lose 1-2lbs a week taking nothing, or even simple combos with yohimbine, to me, theres not a lot of value in taking "risks" simply to burn fat.

Cancer is not shown in humans.

 

[pyrobatt]

pyrobatt

In a rat model, AMPk activation has been shown to suppress protein synthesis by down regulating another molecular target called the mammalian target of rapomyacin, or mTOR which is heavily involved in protein synthesis.

Bolster, DR. AMP-activated protein kinase supresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapomyacin (mTOR) signaling. J Biol Chem (2002) 277: 23977-23980.

Not with gw as it has the same effect as exercise induced ampk activation and if you do research that specifically you will find there's no such effect.

 

[EMPIREMIND]

maybe because theres lots of evidence of it causing cancer? ive seen companies talk about staying away from it, then proceed to sell it simply because people want it anyways. lol

considering you can easily lose 1-2lbs a week taking nothing, or even simple combos with yohimbine, to me, theres not a lot of value in taking "risks" simply to burn fat.

From what ive seen its a performance enhancer and most effective when stacked with other things. Not just solely for losing fat. Furthermore alot of these type of things are effective for people on a deadline who need fast fat loss, without sacrificing muscle (contest preps). anyone can lose weight, but losing strictly fat quickly is another story. As far as cancer... anything still in the research phase is so early into the game that long term effects cant be determined. Thats a risk you will be taking for sure, whether or not its known to cause.

 

[EMPIREMIND]

I really like slintensity as a gda. I loved recompadrol. Agmatine before my preworkout meal has been awesome and so has ala. Also i really like swansons berberine complex.

 

[T-Bone]

You guys made me cancel my order on that GW. I've been reading some labs and it seemed fairly good. A lot of lipid balance/blood pressure changes for the better but not a lot as far as "results" go.

Still wondering why all the hate

It didn't do a thing for lipids for me. Yes I had blood work. No reduction in BP. No increase in endurance. Like I said before it was like a really really really strong GDA though. Had to constantly eat carbs, otherwise I'd pass out from blood sugar so low. That was the only benefit though if you want to call it a "benefit".

 

[xo0ox]

Not with gw as it has the same effect as exercise induced ampk activation and if you do research that specifically you will find there's no such effect.

How about burn24 and ampk activation?
Same as workout induced or more?

 

[pyrobatt]

How about burn24 and ampk activation?
Same as workout induced or more?

What ingredient specifically?

The berberine is under dosed I can say.

 

[squirtguns89]

Cancer is not shown in humans.

based on what? a couple studies done after it was cancelled from further research due to all the red flags? based on some conspiracy that it was just TOO awesome for them to release so they over exaggerated possibly cancer risks? not to mention whatever studies or anecdotal experiences provided, have not been long term. no, we dont know what a lot of these do long term, but at least other sarms/supplements generally arnt breeding grounds for cancer right off the bat.

From what ive seen its a performance enhancer and most effective when stacked with other things. Not just solely for losing fat. Furthermore alot of these type of things are effective for people on a deadline who need fast fat loss, without sacrificing muscle (contest preps). anyone can lose weight, but losing strictly fat quickly is another story. As far as cancer... anything still in the research phase is so early into the game that long term effects cant be determined. Thats a risk you will be taking for sure, whether or not its known to cause.

i can think of quite a few things that boost performance better. maybe less so for the endurance aspect ive heard of, but thats a pretty obscure use for it as far as how majority of people are taking it, unless theres an overwhelming amount of endurance athletes sitting on the forums here im not aware of. majority of real competing bodybuilders are already on cycles providing much more benefits that doesnt merit the possible risk vs possible marginal reward for taking gw again IMO...which is all besides the point, because id guess the majority of people taking the stuff dont compete.

not trying to sound dismissive, as i realize youre just making a point(fair enough), im just being realistic here.

 

[EMPIREMIND]

based on what? a couple studies done after it was cancelled from further research due to all the red flags? based on some conspiracy that it was just TOO awesome for them to release so they over exaggerated possibly cancer risks? not to mention whatever studies or anecdotal experiences provided, have not been long term. no, we dont know what a lot of these do long term, but at least other sarms/supplements generally arnt breeding grounds for cancer right off the bat.



i can think of quite a few things that boost performance better. maybe less so for the endurance aspect ive heard of, but thats a pretty obscure use for it as far as how majority of people are taking it, unless theres an overwhelming amount of endurance athletes sitting on the forums here im not aware of. majority of real competing bodybuilders are already on cycles providing much more benefits that doesnt merit the possible risk vs possible marginal reward for taking gw again IMO...which is all besides the point, because id guess the majority of people taking the stuff dont compete.

not trying to sound dismissive, as i realize youre just making a point(fair enough), im just being realistic here.

Yea i hear u man. You make some good points. I have no personal experience, but i read a little and it seems to have its use in certain sscenarios, again ive never taken so who knows. Also from what i heard, the rats in the cancer study were given amounts that are far far far more than a human would comsume.

 

[pyrobatt]

based on what? a couple studies done after it was cancelled from further research due to all the red flags? based on some conspiracy that it was just TOO awesome for them to release so they over exaggerated possibly cancer risks? not to mention whatever studies or anecdotal experiences provided, have not been long term. no, we dont know what a lot of these do long term, but at least other sarms/supplements generally arnt breeding grounds for cancer right off the bat.



i can think of quite a few things that boost performance better. maybe less so for the endurance aspect ive heard of, but thats a pretty obscure use for it as far as how majority of people are taking it, unless theres an overwhelming amount of endurance athletes sitting on the forums here im not aware of. majority of real competing bodybuilders are already on cycles providing much more benefits that doesnt merit the possible risk vs possible marginal reward for taking gw again IMO...which is all besides the point, because id guess the majority of people taking the stuff dont compete.

not trying to sound dismissive, as i realize youre just making a point(fair enough), im just being realistic here.

They mega dosed the rats....and couldn't re produce in proper dosages...
Maybe that's what it is based on...

And I DO NOT endorse taking 900mg of gw daily for several weeks.

 

[goodvibes]

Not with gw as it has the same effect as exercise induced ampk activation and if you do research that specifically you will find there's no such effect.

If you have a reference pls post so I can read up on it.

 

[iThrow]

read studies that also showed severe mega dosing... in reality id be runnint 7/7/14/14/14/14... thats pretty low compared to the studies

 

[xo0ox]

What ingredient specifically?

The berberine is under dosed I can say.

Yea I was thinking about the berberine.
Was concerned about the Atrogin-1 activation effectively canceling out mTOR and could cause muscle degeneration.

Have been taking burn24 3 caps day = 300mg berbarine / Day

 

[Whacked]

Are any of these good taken with food? 30 minutes pre is a bit annoying lol

 

[aaronuconn]

Yea I was thinking about the berberine.
Was concerned about the Atrogin-1 activation effectively canceling out mTOR and could cause muscle degeneration.

Have been taking burn24 3 caps day = 300mg berbarine / Day

I personally feel Berebrine's downstream impact on mTOR is either overstated or misunderstood. AMPk and mTOR are kind on this seesaw - if AMPk is elevated, mTOR is lowered. If you're consuming enough protein throughout the day, IMO, I wouldn't over-think it.

 

[NoAddedHmones]

Yea I was thinking about the berberine.
Was concerned about the Atrogin-1 activation effectively canceling out mTOR and could cause muscle degeneration.

Have been taking burn24 3 caps day = 300mg berbarine / Day

Lol i've taken 1.5g bolus dosages pre meal many many times. I am having no problems with gainzz.

 

[louisaboy]

Slintensity

 

[heavylifter33]

Kind of late to this party, but i just finished up a bottle of Ostarine from Olympus and one of the biggest things i noticed was that it felt like i was using a GDA. A potent GDA at that. I'm not super up to date on the literature of Ostarine but that was really surprising to me. I was running 30mg ED, split between my 2 biggest meals. Otherwise, i've relied on Glycophase, and then Slin Sane v1 before that.

 

[NoAddedHmones]

Kind of late to this party, but i just finished up a bottle of Ostarine from Olympus and one of the biggest things i noticed was that it felt like i was using a GDA. A potent GDA at that. I'm not super up to date on the literature of Ostarine but that was really surprising to me. I was running 30mg ED, split between my 2 biggest meals. Otherwise, i've relied on Glycophase, and then Slin Sane v1 before that.

Other than GDA effect, what else did you get out of your osta cycle? both good and bad.

 

[xo0ox]

I personally feel Berebrine's downstream impact on mTOR is either overstated or misunderstood. AMPk and mTOR are kind on this seesaw - if AMPk is elevated, mTOR is lowered. If you're consuming enough protein throughout the day, IMO, I wouldn't over-think it.

Ok I'm at about 3.2 grams of protein/ body weight / day.
About 40grams of those is amino acids high in leucine.
I also take Phosphatidic Acid that's suppose to raise mTOR activity.

Lol i've taken 1.5g bolus dosages pre meal many many times. I am having no problems with gainzz.

So 300mg day is a piss in the ocean then

 

[Quads_of_Stee]

Are any of these good taken with food? 30 minutes pre is a bit annoying lol

from what I remember 30-45min pre is the ideal situation in which recompman (ebf recompadrol) stated it could also be taken directly with food or very shortly prior to it but you will not get the full effects.

I personally feel Berebrine's downstream impact on mTOR is either overstated or misunderstood. AMPk and mTOR are kind on this seesaw - if AMPk is elevated, mTOR is lowered. If you're consuming enough protein throughout the day, IMO, I wouldn't over-think it.

I feel this is a trend with many things lately. People are focusing too much on boosting every pathway possible and going out of their way to do it when these things result in a very small percentage of change

 

[T-Bone]

Some severe OCD up in this thread. Some of you should seek treatment.

 

[heavylifter33]

Other than GDA effect, what else did you get out of your osta cycle? both good and bad.

i stopped lifting so my thoughts would be pretty irrelevant. My training is running and calisthenics.

 

[T-Bone]

i stopped lifting so my thoughts would be pretty irrelevant. My training is running and calisthenics.

Can't tell if you're joking or not.

 

[thescience]

Natures way makes a standardized gymnema, something like 75% active content which u can get on an auction for 8 bucks. Ive ordered bulk corosolic acid at somethig like 90% actice extract and found it didnt deliver alone. The gymnemia will get u from zero to hypoglycemic in one cap if you wait too long before eating

 

[thescience]

How much r u guys dosing nar-ala for that effect?

 

[kbayne]

Lol i've taken 1.5g bolus dosages pre meal many many times. I am having no problems with gainzz.

1.5 grams in one dose? Damn lol.

Ok I'm at about 3.2 grams of protein/ body weight / day.
About 40grams of those is amino acids high in leucine.
I also take Phosphatidic Acid that's suppose to raise mTOR activity.

3.2 grams per pound of bodyweight?

That is extremely high and not needed.

Cutting = 1.0-1.5 g/lb
Bulking = 0.8-1.2 g/lb

 

[kbayne]

I personally feel Berebrine's downstream impact on mTOR is either overstated or misunderstood. AMPk and mTOR are kind on this seesaw - if AMPk is elevated, mTOR is lowered. If you're consuming enough protein throughout the day, IMO, I wouldn't over-think it.

This and if you perform resistance training and/or high intensity cardio, I wouldn't worry about Berberine negative impact on muscle hypertrophy.

If you are worried, just dose away from the workout.

 

[NoAddedHmones]

1.5 grams in one dose? Damn lol.



3.2 grams per pound of bodyweight?

That is extremely high and not needed.

Cutting = 1.0-1.5 g/lb
Bulking = 0.8-1.2 g/lb

Give it a try next time you are wanted to feel very full from a meal.

 

[xo0ox]

1.5 grams in one dose? Damn lol.



3.2 grams per pound of bodyweight?

That is extremely high and not needed.

Cutting = 1.0-1.5 g/lb
Bulking = 0.8-1.2 g/lb

Haha no, per kg body weight
For me that is about 250g protein / Day

Last messurment (14 Point caliper) i'm down to 6% body fat...
Soon going on a reverse...

 

[kbayne]

Okay that sounds better lol.

 

[heavylifter33]

Can't tell if you're joking or not.

Unfortunately i'm not joking. Actively trying to lose weight/muscle. Training for something specific and i need to be about 185, i was 215. Currently 200.

 

[pyrobatt]

Unfortunately i'm not joking. Actively trying to lose weight/muscle. Training for something specific and i need to be about 185, i was 215. Currently 200.

Train for your goals man.

Trying to make weight can be a bitch especially if you are a seasoned lifter. Take jerry ward for instance, he lost a **** ton of muscle on purpose to compete in physique vs bodybuilding.

What's got you shedding the pounds brother? If you don't mind me asking that is. I don't think porn has a weight class so my first guess is out

 

[T-Bone]

Unfortunately i'm not joking. Actively trying to lose weight/muscle. Training for something specific and i need to be about 185, i was 215. Currently 200.

What's that you are training for?. Boxing/fighting?.

 

[xo0ox]

Unfortunately i'm not joking. Actively trying to lose weight/muscle. Training for something specific and i need to be about 185, i was 215. Currently 200.

Best of luck to you and keep you eye on the goal and you will make it.

 

[Piledahlaren]

I dont see anyone talking about gymnema sylvestre?? what do you think about it?
I take 400mg (24%) 15min pre highcarb meal

 

[pyrobatt]

I dont see anyone talking about gymnema sylvestre?? what do you think about it?
I take 400mg (24%) 15min pre highcarb meal

I think bulk cinnamon extract is a better alternative tbh.

 

[Piledahlaren]

I think bulk cinnamon extract is a better alternative tbh.

Thanks, will try it with banaba

 

[pyrobatt]

Thanks, will try it with banaba

They come in 1g capsules at Sam's Club (in the us) or other places.

They are researched heavily in regards to blood sugar control and type 2 diabetics. If they can be used as an alternative to a drug called Glucophage. ...that means they are Hella effective.

I have induced dizziness by taking too much.

Low blood sugar.

I have found that past 2g is where I start noticing low bs.

Per day by the way.

 

[Whacked]

Sup Pyro

Are you taking the cinnamon with food or 30-45 min PRE

 

[pyrobatt]

Sup Pyro

Are you taking the cinnamon with food or 30-45 min PRE

Never take a gda pre workout. I just take it when I can

 

[Whacked]

So you're taking it with food and going hypo?

 

[booneman77]

Never take a gda pre workout. I just take it when I can

I think he meant pre meal.

 

[pyrobatt]

I think he meant pre meal.

Oh yeah. Pre meal or with meal.

 

[pyrobatt]

So you're taking it with food and going hypo?

I can if I take 4 to 7 grams of the stuff. 1g to 6g is the dosage. Per day.

I can't handle more than 4 usually.

Cheap and effective

 

[pyrobatt]

why not?

Low blood sugar.

Not only can it reduce performance via fatigue and mental fog but can be deadly.

Imagine passing out at the top of your squat with 400+lbs on your back.

If you're training with enough intensity you'll certainly feel hypo rather quickly if you take it pre workout.

 

[highlander31]

I can if I take 4 to 7 grams of the stuff. 1g to 6g is the dosage. Per day.

I can't handle more than 4 usually.

Cheap and effective

do you know the type of cinnamon? Theres some literature out there showing Cassia can have some serious negatives in higher dosages (forget the dose but if I recall around 5g). The Ceylon (cant remember spelling) is the one to look for and its hard to find it capped, so if Sams Club has that capped im sold.

 

[highlander31]

Low blood sugar.

Not only can it reduce performance via fatigue and mental fog but can be deadly.

Imagine passing out at the top of your squat with 400+lbs on your back.

If you're training with enough intensity you'll certainly feel hypo rather quickly if you take it pre workout.

I hear ya, but that would be with no carb intake pre or intra yes? Ive used some GDAs pre-workout and dose about 50g carbs pre with it and 50g carbs intra and must say I have loved it. Dont do it exclusively, but have tried and did like it.

 

[pyrobatt]

I hear ya, but that would be with no carb intake pre or intra yes? Ive used some GDAs pre-workout and dose about 50g carbs pre with it and 50g carbs intra and must say I have loved it. Dont do it exclusively, but have tried and did like it.

I have on average 70g carbs pre workout.

It's individual. GDAs are used to control blood sugar most of the time.

Intra carbs are imo useless unless you're an endurance athlete or a pro athlete. But that's for another topic another day.

 

[pyrobatt]

do you know the type of cinnamon? Theres some literature out there showing Cassia can have some serious negatives in higher dosages (forget the dose but if I recall around 5g). The Ceylon (cant remember spelling) is the one to look for and its hard to find it capped, so if Sams Club has that capped im sold.

Cin-max(Sams club) is cassia but you don't have liver disease so...your safe. If taken in large amounts it can be damaging but we wont. 1 to 6g daily will be just fine.

Oh and don't take any GDAS before surgery.

I personally opt for 1 to 3g .