I really wish lsd was not illegal. I truly believe that this could be a serious game changer in mental health diseases
Yeah there’s a lot of buzz now about so called micro dosing lsd as a treatment for various illnesses. Though it being schedule 1 in the US it will likely never get tested for such purposes, at least not any time soon. And we will have to go off anecdotal reports, or shotty trials run by other countries, though even that is unlikely. The more likely scenario is to find other compounds that have the same receptor binding affinities as lsd in these small doses and then test those analogs as a non scheduled drug.I really wish lsd was not illegal. I truly believe that this could be a serious game changer in mental health diseases
There is actually study I heard of where people use psychedelics and empathogens responsibly ,key word ,-responsible people, have slightly better mental health than people who never used them. I didnt see the study, just heard about itI really wish lsd was not illegal. I truly believe that this could be a serious game changer in mental health diseases
Yep, I completely agree with this. California is moving to try and legalize psilocybin now, so the thought process is gaining on a larger scale. Not LSD, but still has shown to have positive effects on people- especially those with chronic migraines.I really wish lsd was not illegal. I truly believe that this could be a serious game changer in mental health diseases
I was speaking specifically about physiological, stress induced, low CO2 blood levels, not brain chemistry related stuff. Remember the old "breathing in a paper bag"? Well... Research it. I'm surprised you dismissed it so quickly.I can tell you that using a breathe right and taping your mouth shut isn't going to help anyone other than maybe you. LOL
I had the same results (or lack of notable results) from emoxypine. However, I only used it for a week or two.I've tried emoxypine from a few distributors and to completely honest, I cannot say if it works. It may, but the effects are very subtle. I would be curious if this is something that works better for long term use as it does have some health benefits.
Tried one sample but didn't notice anything.Has anyone tried bromantane?
Maybe it has something to do with the low dosage...or me just being weird...or both? I don't know. I just know I focus much better at work (get a lot done) and actually leave my office to talk to people occasionally.Wow, that is very strange indeed. That is the exact opposite of what you would think would happen. For me, I don't want to be around people, I just want to get things done and not be bothered. When I am interrupted I get very agitated and when in social situations, just want to get away.
Use to be a daily smoker. But get bad anxiety alsoNo. I used to love pot tho. It gives me anxiety now like nothing else.
I've heard in legal states there are good strands for anxiety but at this point I almost find it hard to believe.
You are prob a “responder” to modafinil. Unfortunately it doesn’t do much for me. They think the enhancing effects of the drug are related to whether or not you have a specific variant in a dopamine gene. I have the one version of the gene shown in studies to not respond to modafinil. Or at least for me it doesn’t do anything caffeine doesn’t do. It’s a very interesting drug though, and influences practically every neurotransmitter, so it can deff elevate mood, especially if you are stim sensitive.Tried one sample but didn't notice anything.
Strangely enough (considering how stim sensitive I am), 50 mg of modafinil really reduces my social anxiety (and depression).
The influence stimulants have on personality or behavior likely stems from whatever personality type you are to begin with. If you are an introvert like me, and an analyst (NT), likely stims will make you want to get away from people and get back to being “productive”, whereas I know extroverted individuals that might have anxiety or lack of confidence but want to socialize find stims let them get out of their shell some and be more like themselves.Wow, that is very strange indeed. That is the exact opposite of what you would think would happen. For me, I don't want to be around people, I just want to get things done and not be bothered. When I am interrupted I get very agitated and when in social situations, just want to get away.
The key is finding a non-addictive combination of compounds that tackles anxiety from all angles.Sup brahs,
So I battle mild-ish anxiety. It's on and off throughout the day of me typically freaking out about my heart. I also feel like my heart beat is rapid or I'm having a heart attack lol (I know this isn't true from checking my pulse, having others, seeing a doc about heart health, etc.)
I'm sure some of you with anxiety know what I'm talking about. It's pretty stupid, but it ****s me up.
I've seen a lot of bros recommend different things for anxiety. So those of you who've tried what do you recommend?
Note: I have not tried taking anything at this point to try to combat my anxiety. I do not wish to go on any prescription drugs either. But I've seen people say about pregnolone, kratom, dopamine, etc
That's how it effects me as wellYou are prob a “responder” to modafinil. Unfortunately it doesn’t do much for me. They think the enhancing effects of the drug are related to whether or not you have a specific variant in a dopamine gene. I have the one version of the gene shown in studies to not respond to modafinil. Or at least for me it doesn’t do anything caffeine doesn’t do. It’s a very interesting drug though, and influences practically every neurotransmitter, so it can deff elevate mood, especially if you are stim sensitive.
No, it actually has to do with the chemical structure of modafinil. Having R and the S isomers, if you are an extrovert, like I am, it typically will make you very alert and talkative, but only about whatever task you are focused on at that time. Modafinil "feels" much stronger and is very task oriented. Interruptions to these tasks can be irritating. It's not really a social stimulant, but more of a "let's get things done".The influence stimulants have on personality or behavior likely stems from whatever personality type you are to begin with. If you are an introvert like me, and an analyst (NT), likely stims will make you want to get away from people and get back to being “productive”, whereas I know extroverted individuals that might have anxiety or lack of confidence but want to socialize find stims let them get out of their shell some and be more like themselves.
Well said brother. Agreed.Are you on long term prescription drugs like ssri's, ssni's to boost happy chemicals?
going low is part of the process, thats when the weak crumble. I know its cliche, when you least expect it, when things are at their lowest, things get better.
I will say that when I take GABA in its regular form I deff get an anxiolytic effect. I’ve tried it multiple times and ruled out placebo just from the consistency with each dose. However, all the research out there says GABA taken orally doesn’t really get through the BBB...so this is one of those issues that I will say I’d go off personal experimentation rather than the research. Maybe it works indirectly through other neurotransmitters or decreases cns gaba efflux. Idk but I deff think it’s a good alternative to Rx anxiolytics, assuming panic attacks or ptsd isn’t the issue being treatedFor me it’s Kratom and 5-HTP. I’m very responsive to 5-HTP and haven’t gotten the dosing right yet but it seems like 50-75mg daily and it works better than the Paroxetine that I recently quit taking after being on for 4 years. Next step is to drop the Kratom and add either GABA or Picamillon. Phenibut is great but like many have stated it is addictive and has the same downsides as benzodiazepines. I tried picamillon once but maybe I was looking for it to be as strong as phenibut.
Emoxypine is an antioxidant that is similar in chemical structure to Pyridoxine (Vitamin B6). Its mechanism of action involves its ability to function as an antioxidant and its membrane protective effects.
Users of this supplement can expect to experience anti-stress, neuroprotective effects, anti-inflammation and nootropic properties when using this ingredient. This is due to its ability to inhibit free radical oxidation, increase the activity of antioxidant enzymes, play a key role in the modulation of the receptor complexes of the brain membranes and the activity of membrane-bound enzymes, stabilise bio-membranes and increase the dopamine content in the brain.
Choline and Vitamin B-12 could be a significantly cheaper substitute for Emoxypine. CDP and Alpha-GPC have been shown to increase BDNF, improve neurotransmittion and is a component of membrane sheaths.I would be curious if this is something that works better for long term use as it does have some health benefits.
Look into lavender oil capsules 80 mg per. The burps taste disgusting (in my opinion, which is why I stopped it. Some like it tho or don’t experience it) but it’s very effective for the type of anxiety you have.i have anxiety issues. I do not want to go the route of prescriptions and have tried to manage it on my own through, exercise and running. Im on holy basil and kava kava during the day, and I take valerian at night as i have sleep problems. So far im managing. Anxiety sucks, sometimes im literally paralyze with fear. I have turned to my Catholic roots and researched the bibles take on it, this is helpful for those that want to take that route. Phenibut was helpful, but i only took it sporadically as I know its addicting, and really the only thing I want to be addicted to is training.
That's a really ignorant and asinine view that you share with someone clearly uneducated on mental disorders. As someone who did grad work in the neurological disorder field as well as in the industry for years it is simply idiotic to have the "just be tough and get over it" mindset. We're not talking about something acute like a breakup or that your dog died. In that sense yes, it's likely unnecessary to pursue medication to treat it. It's certainly depressing but it will fade and you can likely get through it by yourself or with counseling. However, with a Chronic disorder, that is simply not the case. In many cases it's a matter of biochemical imbalances with various substrates/receptors/chemicals/etc. and you can't "will" your body to start producing chemicals that it simply isn't capable of producing. And in many cases counseling is simply a waste of time, because nothing is "wrong". You can't talk your system into changing. The options usually end up being either medication that corrects the imbalances or you just sit there in your depressive or anxious state. And to call the medications "happy pills" is just as asinine. When you have a chemical deficiency and you take medication is doesn't make you super happy and giddy. All it does is put your system at a "normal" state and correct the imbalance or deficiency. You don't prance around you just feel as a normal person would. Which in many cases is the point. It reduces the, in many cases, extremely negative symptoms of the disorder. You don't feel giddy you just don't feel extremely depressed/anxious/etc. which is the normal state of your body. I would hope that you, and everyone for that matter, perform the proper and adequate research to have an educated perspective on the subject before offending those who live it every day.Well said brother. Agreed.
Well said! Also there is no such thing as a happy pill. Dexedrine is the closest thing to happy pill IME, and that I don't even talk anymore. I think it made my problem worse.That's a really ignorant and asinine view that you share with someone clearly uneducated on mental disorders. As someone who did grad work in the neurological disorder field as well as in the industry for years it is simply idiotic to have the "just be tough and get over it" mindset. We're not talking about something acute like a breakup or that your dog died. In that sense yes, it's likely unnecessary to pursue medication to treat it. It's certainly depressing but it will fade and you can likely get through it by yourself or with counseling. However, with a Chronic disorder, that is simply not the case. In many cases it's a matter of biochemical imbalances with various substrates/receptors/chemicals/etc. and you can't "will" your body to start producing chemicals that it simply isn't capable of producing. And in many cases counseling is simply a waste of time, because nothing is "wrong". You can't talk your system into changing. The options usually end up being either medication that corrects the imbalances or you just sit there in your depressive or anxious state. And to call the medications "happy pills" is just as asinine. When you have a chemical deficiency and you take medication is doesn't make you super happy and giddy. All it does is put your system at a "normal" state and correct the imbalance or deficiency. You don't prance around you just feel as a normal person would. Which in many cases is the point. It reduces the, in many cases, extremely negative symptoms of the disorder. You don't feel giddy you just don't feel extremely depressed/anxious/etc. which is the normal state of your body. I would hope that you, and everyone for that matter, perform the proper and adequate research to have an educated perspective on the subject before offending those who live it every day.
Coming off an SSRI was one of the scariest things I've ever had to do. It was like a month long panic attack with the ****ing brain zaps, but it was worth it for what I was able to get through when on it.Anyone who has ever taken and SSRIs know how much they suck. At least at first, and for some the side effects never go away. These medication present just as much challenges as if you weren't taking them, but they allow you to overcome things that you previous couldn't, as a chemical imbalance wouldn't allow you to.
Brain zaps those were miserable. Did you ever get the sensation that feels like your brain was sunburnt?Coming off an SSRI was one of the scariest things I've ever had to do. It was like a month long panic attack with the ****ing brain zaps, but it was worth it for what I was able to get through when on it.
No, I was spared that, but the whole experience just sucked. I wanted to start taking them again to make it stop, but knew I needed to power through.Brain zaps those were miserable. Did you ever get the sensation that feels like your brain was sunburnt?
Can you explain a brain zap? I’ve heard this a lot but have no idea what it is or how it would be described. I’m genuinely interested.No, I was spared that, but the whole experience just sucked. I wanted to start taking them again to make it stop, but knew I needed to power through.
Honestly it's indescribable, unless you've experienced. Its like trying to describe an lsd trip, of which you've "entered" a dimension, which you don't even understand, to a person who's never used any drugs.Can you explain a brain zap? I’ve heard this a lot but have no idea what it is or how it would be described. I’m genuinely interested.
^^^^^^^^^^^^^^^That's a really ignorant and asinine view that you share with someone clearly uneducated on mental disorders. As someone who did grad work in the neurological disorder field as well as in the industry for years it is simply idiotic to have the "just be tough and get over it" mindset. We're not talking about something acute like a breakup or that your dog died. In that sense yes, it's likely unnecessary to pursue medication to treat it. It's certainly depressing but it will fade and you can likely get through it by yourself or with counseling. However, with a Chronic disorder, that is simply not the case. In many cases it's a matter of biochemical imbalances with various substrates/receptors/chemicals/etc. and you can't "will" your body to start producing chemicals that it simply isn't capable of producing. And in many cases counseling is simply a waste of time, because nothing is "wrong". You can't talk your system into changing. The options usually end up being either medication that corrects the imbalances or you just sit there in your depressive or anxious state. And to call the medications "happy pills" is just as asinine. When you have a chemical deficiency and you take medication is doesn't make you super happy and giddy. All it does is put your system at a "normal" state and correct the imbalance or deficiency. You don't prance around you just feel as a normal person would. Which in many cases is the point. It reduces the, in many cases, extremely negative symptoms of the disorder. You don't feel giddy you just don't feel extremely depressed/anxious/etc. which is the normal state of your body. I would hope that you, and everyone for that matter, perform the proper and adequate research to have an educated perspective on the subject before offending those who live it every day.
Have you ever had a minor electric shock? I guess the best way I can explain it is that it felt like that in my head. I can't recall a specific region that it happened in and would occur at random. There would be sometimes though that it would happen repeatedly in a day. I was finishing up a post-doc at the time and could barely do my work for that month. The mechanism of action isn't really understood, so I'm guessing it's just from the body acclimating back to "normal."Can you explain a brain zap? I’ve heard this a lot but have no idea what it is or how it would be described. I’m genuinely interested.
It seems it's out of stock. Any estimated date?Hydrapharm Emoxypine can be used for the long-term to provide neuro-protective effects, anti-stress and anti-anxiety effects, anti-oxidant benefits and anti-inflammatory effects.
It works differently to all other nootropics as it helps to protect neurons and increase blood flow to the brain, whereas other nootropics exert their influence or alter the behaviour of neurotransmitters in the brain.
talk to a doctor,and if they dont help you talk to another one and another one, xanax should only be used sparingly and in extreme situations.I suffer from Anxiety and Agoraphobia and it really sucks.
I always have been a very "nervous" person but i never stopped doing anything because of that. However, since my first panic attack occured, things got really worse and i started to avoid every single situation where i got one. Agoraphobia developed and life quality reduced massively. I stopped doing things i like for fearing a new panic attack.
The only prescribed drug i take is Alprazolam only when needed which is very very rare since i avoid most of the problematic situations. I took an SSRI for a month many years ago when i didn't know anything about them but now i refuse to take them... Those possible side effects really scare me. Maybe i'm not doing the right choose but who knows...
About supplements i already tried a lot of things and unfortunately i never found one which really helped me. Some of them seems to calm me a little more if i'm already "calmed" but none of them seems to help in accute situations. Neither Alprazolam (0.5 - 1mg dosages) does miracles.
I suspect there must be a chemical imbalance in my body because my father suffers from the same thing , so i guess it's something inherited. I wish to know what and how could i fix it.
After trying many supplements it seems the few that somehow works on me are the ones which reduces Cortisol. I'm currently taking Ashwagandha and Relora and it seems they are helping a little. They don't prevent Anxiety but it seems i can manage it better. On the other hand, last time i took 5HTP i felt really really worse. When searching, i found out 5HTP could increase Cortisol. So maybe i'm getting somewhere. I don't know if Cortisol is the main cause or a symptom of the main problem but it seems to be related with my Anxiety.
Any thoughts about that? Theres anything stronger (and preferably side effects free) i could try to reduce Cortisol to see how things will go?
I actually have a diagnosed anxiety disorder and I’ve recently tapered off an SSRI. I’m continuing to learn better coping methods as well as trying more natural approaches. I mean no disrespect in agreeing with his statement. What I have noticed in myself though is that sometimes I find myself looking at myself a little too much. I think there’s a balance required of acknowledging the disorder without bathing in self pity and I think that I do that from time to time. Anxiety attacks tend to start a negative thought pattern and it’s easy for me to become ungrateful for the things that are right in my life. I should have been more specific by stating that maybe that’s what I needed to hear at the moment.That's a really ignorant and asinine view that you share with someone clearly uneducated on mental disorders. As someone who did grad work in the neurological disorder field as well as in the industry for years it is simply idiotic to have the "just be tough and get over it" mindset. We're not talking about something acute like a breakup or that your dog died. In that sense yes, it's likely unnecessary to pursue medication to treat it. It's certainly depressing but it will fade and you can likely get through it by yourself or with counseling. However, with a Chronic disorder, that is simply not the case. In many cases it's a matter of biochemical imbalances with various substrates/receptors/chemicals/etc. and you can't "will" your body to start producing chemicals that it simply isn't capable of producing. And in many cases counseling is simply a waste of time, because nothing is "wrong". You can't talk your system into changing. The options usually end up being either medication that corrects the imbalances or you just sit there in your depressive or anxious state. And to call the medications "happy pills" is just as asinine. When you have a chemical deficiency and you take medication is doesn't make you super happy and giddy. All it does is put your system at a "normal" state and correct the imbalance or deficiency. You don't prance around you just feel as a normal person would. Which in many cases is the point. It reduces the, in many cases, extremely negative symptoms of the disorder. You don't feel giddy you just don't feel extremely depressed/anxious/etc. which is the normal state of your body. I would hope that you, and everyone for that matter, perform the proper and adequate research to have an educated perspective on the subject before offending those who live it every day.
Im glad you got off an SSRI. I was once on three or so drugs at once, I didn't even know what they had me all on. Wellbutrin was one. anyways it was a very,very low point, I wasnt myself, withdrew, cried, depressed, felt sorry for myself. Self pity causes an opiate certain feeling thats addictive, and as everyone knows tolerance builds and to get the same effect you must do more and more to get that "high". Its cliche; however so very, very true, Thoughts are powerful. I still cry.I actually have a diagnosed anxiety disorder and I’ve recently tapered off an SSRI. I’m continuing to learn better coping methods as well as trying more natural approaches. I mean no disrespect in agreeing with his statement. What I have noticed in myself though is that sometimes I find myself looking at myself a little too much. I think there’s a balance required of acknowledging the disorder without bathing in self pity and I think that I do that from time to time. Anxiety attacks tend to start a negative thought pattern and it’s easy for me to become ungrateful for the things that are right in my life. I should have been more specific by stating that maybe that’s what I needed to hear at the moment.
Some like it, I found it did nothing really. Part of the issue is that it is not acute in action and therefore it's difficult to know when it is actually working or if it is at all.How effective is Bacopa for anxiety and sleep/insomnia issues? I currently take KSM-66, which helps with anxiety and calmness, but does not help with my insomnia or obsessive thoughts. I have heard that Bacopa is sedative for some people, might be worth to try, right?
Silexan I think is a better approach. It's an herbal drug for sleep, anxiety, etc but safe and effective.How effective is Bacopa for anxiety and sleep/insomnia issues? I currently take KSM-66, which helps with anxiety and calmness, but does not help with my insomnia or obsessive thoughts. I have heard that Bacopa is sedative for some people, might be worth to try, right?
I’m thinking of going this route just to have a safety net. I would probably have peace of mind knowing that I have that option.I was curious if it was Propranolol. I know a few executives that swear by it before large meetings.
I didn’t get brain zaps this time. It was actually about 5-6 weeks before it really got rough. I missed work on a Thursday and Friday with flu-like symptoms. My faith is most definitely stronger now though.No, I was spared that, but the whole experience just sucked. I wanted to start taking them again to make it stop, but knew I needed to power through.
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