All of those other chemicals are in hand creams makeup,and all other topical creams no matter what they are.Each of those on their own are able to get through the skin. There is no need to worry. Talk to ya..
It depends on what concetrations are present in your "alternative" to determine how effective it will be as a carrier. It has a few good enhancers but most will have them in the 1-3% range...a good homebrew will have no less than 50% of the volume as enhancers.Originally posted by CHEORKEE
Ok....I havn't had an opportunity to go by the friendly farm supply store to pick up the DMSO. However, I do have a question. I have some stuff here that is for muscle pain. Basically it's:
Camphor
Methol
Methl Salicylate
Glycerl Sterate
Isopropyl Myristate
Alcohol
and some other **** that I've never heard of.
The question is, can this be used a transdermal catalist in lew of the DMSO?
Also, I've come across.....some other stuff that contains Emew (wrong spelling) oil as the catalist.
Any comments is appreciated.
P.S. I'm new to the board so how else to get thing rolling along except ask a few questions.
Thanks
Cherokee
First of all, welcome YE. Yes, the BCD gel is similar to the HB recipie and yes added carbomer and d-lim are what make that difference. You may want to ask BDC how much % of each he uses and how he mixes it, If you want the gel. Good luckHello, this is my first post and Im glad to have found such a unique board.
Is BDC's T-gel the same as the homebrew formula?>
40% ISOPROPYL ALCOHOL( ISO )
15% ISOPROPYL MYRISTRATE( IPM )
15% ISOPROPYL PALMITATE( IPP )
10% OLEIC ACID( OA )
10% PROPYLENE GLYCOL( PG )
10% DMSO
I understand that the only difference Between the T-gel and "homebrew" is an added carbomer and d-lime, Is this right?
Thanks -Your Endo
Hey Chemo, Curt, KitchenChemist et al..........
First, welcome to the board!
When we say to keep it low the intention is too keep it around 50 mg/mL concentration. This has been shown to optimize the absorption. This is 12 grams of *WHATEVER* in solution and can be a combination of 1-test/4-AD/fina/test base or anything else desired. Now, above and below 50 the absorption will have diminished returns but is marginal when viewed in terms of a DMSO recipe.
I would definitely recommend the DMSO no matter what. If you opt to leave the PG or Glycerol out would be OK but will make for more irritation and drying...you're choice.
The 40% estimate is for the DMSO recipe. If you go with the IPM and OA it may be 10-15%...
Chemo
The thickening agents do not add significant volume (use .5 grams of each, carbomer and methyl cellulose) so the formula is not diluted. The addition of methyl cellulose was added to help with those that were adding powders other than PH's. In the case of a pellet, the methyl cellulose binders were leaching the water soluble ingredients and causing the gel to stratify (separate into layers). If you add the methyl cellulose to begin with and process for a gel you effectively eliminate the stratification.Originally posted by Your Endo
Also,
Wouldn’t the carbomer gel component “dilute” the BDC transdermal formula? Is the carbomer part added in, or is it just replacing something? If added, it seems to me that the carbomer (gel) component simply dilutes the T-gel over the otherwise “pure” liquid HB form. Sorry about all the Q’s, just a lot I need to know. Please clarify this one for me. Thanks -Your Endo
One change to this gelling recipe: add the thickening agents to the PG/Glycerol (water soluble ingredients) FIRST before adding the alcohol. This is generally easier for homebrewers that do not use a high speed mixer.Originally posted by Kitchen Chemist
Here's intstructions on how chemo makes his forumula, carboomer is not replacing anything as t-gel isn't a liquid it's a gel.
Originally posted by chemo :
Here's my recipe for gelling with carbomer 934 (ingredients are for each 8 oz of gel):
Mix 1 gram carbomer to 120 mL i-prop alcohol, mix well with hand blender or similiar (I use a high speed process mixer)
Add 60 mL IPM, mix well
Add 24 mL OA, mix well
Add 12 mL d-limonene, mix well
Add 24 mL PG or Glycerol, mix well
Add triethanolamine drop-wise until gel is attained.
NOTES:
Carbomer 934 tends to clump when it comes in contact with POLAR SOLVENTS such as i-prop alcohol. If using a hand blender or similiar it can be dispersed easily and this won't be too much of a concern.
If an oil layer develops on the surface add 5% more d-limonene (emulsifier) and mix well again. If the oil layer persists add water dropwise until the gel is attained.
Modify the pH AFTER adding all the ingredients. If you adjust after mixing the i-prop and carbomer the solution will become extremely separated and will not gel.
FOR THE FUTURE:
I am ordering some Carbomer 940 which is designed especially for hydroalcoholic gels and will give crystal clear appearance. When I get some I will offer it to the members at cost. The benefits are the clear consistency and the ease of gelling (it is effective at a wider pH range).
Chemo
The pH is adjusted only if you are interested in gelling the recipe. Also, you will have to add the thickening agents before it will gel.Originally posted by Your Endo
Ok, I’m a little confused as to what “pH” means. I’m assuming that you are referring to the acidic level? If so then how is the pH adjusted? Why? When?
Is it necessary to adjust the pH level for a liquid solution the same as for the gel? This brings me back to the question of why is a liquid even converted to a gel in the first place… ?
Also, I see the “PH” used a lot on this site and I originaly thought it was referring to “Pro-Hormones”. Obviously I am no chemist, so can someone clear this whole (pH, PH) thing up for me?
I’m really interested in this whole homebrew idea and I would love to bring some new found knowledge over to my homeland Meso! (www.Mesomorphosis.com) I’ve got a lot of ideas and I appreciate your help on this guys. –Your Endo
P.S. can someone give me the link to ‘clerk2togo’s’ original thread on how the “Perfect Homebrew” formula got started? I heard it was on bb, but I cant seem find it.
PC1,Originally posted by PC1
Hey Chemo, Curt, KitchenChemist et al..........
Great info on this site. You guys have inspired me to try my first homebrew, which I began just 2 days ago. 6g 4AD + 6g 1 test in the 240 ml bottle. I can tell this will be a very effective PH cycle for me because I already feel some new life coming back into my physique, so thanks very much guys.
Question for you on the application please:
If the absorption rate is somewhere around 40% with the dmso recipe, then it stands to reason the other 60% or so remains on the surface of our skin once dry...... and so it largely is wasted.
That being so, wouldn't it make sense to mix up a second bottle of the homebrew recipe WITHOUT any PH, and say within 20 minutes or so, apply that to the same area and utilize some additional portion of what was left unabsorbed by the first application?
I'm not sure if this is true or not, but if we could utilize 40% again of the 60% that went unabsorbed on the first application, that would effectively be another 24% increase in dosage........ without buying any additional PH? Heck, even if we only got another 10% or 15% out of it, the homebrew ingredients are cheap enough, so it seems worthwhile to do.......... no?
Thanks.
PC1
I'm using this formula without the gel, although I also add an additional 5ml of the limonene as suggested. I know it separates when left to stand. But I have a neat leftover bottle/syringe combo from one of my kid's bad colds (oral antibiotic) this past winter. The top of the bottle has a screw in plastic piece that restricts the opening to exactly the size of the syringe tip. I just shake the hell out of it for 30 seconds, and quickly flip it over and draw out the contents 4ml at a time. It seems to be working really well.Hey PC1, are you using this formula?
40% ISOPROPYL ALCOHOL( ISO )
15% ISOPROPYL MYRISTRATE( IPM )
15% ISOPROPYL PALMITATE( IPP )
10% OLEIC ACID( OA )
10% PROPYLENE GLYCOL( PG )
10% DMSO
Which is liquid, or are you using the gel?
Go to BB.com and look up 2 threads in the supliments part. they are called perfecting homebrew and homebrew perfected. They should answerall your questions. These threads were created about 1 year ago and started the whole homebrewing craze.. heheheh TTYOriginally posted by Your Endo
Chemo, this is in regards to my above post ^ I’m just curios to know if there are any web sites you recommend for me to check. I’m really interested in learning about the whole biological processes of these topic formulas. My basic science knowledge is pretty slim too, so any kind of generic information I could learn from the web would help a lot. Specifically; conversion charts, pH levels, solubility properties, molecular weights, reactions of various chemicals, ect. I’m still waiting for a response to my last post. Anyway thanks again to all. -Your Endo
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