Interesting, my brother used to take it and had no side effects but it depends on the person.
Having no side effects with accutane is rare. Very rare.
Here's a short list of side effects of accutane broken down by category:
Body
allergies
vasculitis
systemic hypersensitivity
edema
fatigue
lympadenopathy
Cardiovascular
palpitation
tachycardia
vascular thrombotic disease
stroke
Endocrine/Metabolic
hypertriglyceridemia (increases triglycerides)
altered blood sugar levels
Gastrointestinal
inflammatory bowel disease
hepatitis (yep, you cna develop a nonviral/nonbacterial form of hepatitis from it)
pancreatitis
bleeding and inflammation of gums
colitis
esophagitis/esophageal ulceration
ileitis
nausea
Hematologic
anemia
thrombocytopenia
neutropenia
Musculoskeletal
skeletal hyperstosis
calcification of tendons and ligaments
decreased bone mineral density
back pain
myalgia
arthralgia
transient chest pain
arthritis
tendonitis
other bone abnormalities
Neurological
pseudotumor cerebri
dizziness
drowsiness
headache
insomnia
lethargy
malaise
nervousness
paresthesias
seizures
syncope
weakness
Psychiatric
suicidal ideation
suicide attempts
suicide
depression
psychosis
aggression
violent behaviors
emotional instability
Respiratory
bronchospasma
Skin and Appendages
acne fulminans
alopecia
bruising
cheilitis (dry lips)
dry mouth
dry nose
dry skin
epistaxis
eruptive xanthomas
flushing
fragiolity of skin (your skin tears very easily)
hair abnormalities
hirsutism
hyperpigmentation and hypopigmentation (more commonly hypo; you can become almost like an albino while on it)
susceptibility to infections
nail dystrophy
paronychia
peeling of palms and soles
photoallergic/photosensitizing reactions
pruritus
pyogenic granuloma
rash
sunburn susceptibility increased (VASTLY)
sweating
urticaria
abnormal wound healing (delayed healing, crusting of wounds, excessive scarring)
Hearing
hearing impairment
Vision
corneal opacities
decreased night vision which may become permanent
cataracts
color vision disorder
conjunctivitis (makes you more susceptible to it)
dry eyes
eylid inflammation
keratitis
optic neuritis
photophobia
visual disturbance
Urinary
glomerulonephritis
nonspecific urogenital findings (EEK!)
Lab test findings
Elevated triglycerides
decrease in HDL cholesterol
increase in LDL cholesterol
Increased AST, ALT, GGTP, and LDH (messes with your liver BIGTIME)
increased blood sugar
decreased red blood cell count
decreased white blood cell count
increased platelet count
whit blood cells in urine
Accutane is some seriously nasty ****.