Ziquor
Well-known member
- Awards
- 1
I found this article on a German website:
The US DEA did in vivo testing with dienolone and boldione (DEA Agreement No. DEA-04-P0007.) Yesterday we reported that the American DEA completed a bill which concludes that DMT, boldione, and dienolone be considered anabolic steroids. The drug agency tested the effects of dienolone, aka 19-nor-4,9(10)-androstadienedione, and boldione, aka 1,4-androstadien-3,17-dione, on rats. The most striking outcome of that study: dienolone is strange stuff.
The research workers, Alvin Matsumoto and Brett Marck, administered rat implants which delivered steady levels of the steroid hormones, and also gave rats in a control group implants without active substances (placebo). Eight weeks after the operation, the researchers looked at the effects on the animals. Boldione raised the concentration of testosterone in the rats. Could the antibodies that the research workers used for the boldione analogue have been confused with testosterone? (See Diagram below) Dienolone raised the levels of estradiol in the animals. That is logical. Dienolone seems to convert fairly easily to estrogen.
The concentrations of LH and FSH, the two driving hormones which induce the testes to produce testosterone, were diminished by the administration of both hormones. Remarkably, after the administration of dienolone the weight of the testes increased. This is seen in the figure below.
Then the researchers tested the anabolic / androgenic properties of the two steroids shown via the sizing of the prostate and the levator ani muscle of the rats, as shown in the diagram below.
From the results you would think that dienolone was a more powerful anabolic / androgen than boldione. However this was not the case. The above figures are in relation to the relative weights: the weight of the levator ani muscle and the total body weight of the rats. The rats that received dienolone had gained less weight than the other animals, but mainly because they were less willing to eat. Below you see the weight increases of the test animals. The rats who received dienolone had a larger increase in the weight of the prostate and levator ani muscle, which was not surprising. The fact that the rats who were administered dienolone had an enlargement of the testes, could not be explained. The research workers think that dienolone decreased the appetite because it converted into estradiol. In 1978, researchers discovered that androgens which convert to estradiol especially decrease ones appetite. Weight changes are shown in the diagram below.
The US DEA did in vivo testing with dienolone and boldione (DEA Agreement No. DEA-04-P0007.) Yesterday we reported that the American DEA completed a bill which concludes that DMT, boldione, and dienolone be considered anabolic steroids. The drug agency tested the effects of dienolone, aka 19-nor-4,9(10)-androstadienedione, and boldione, aka 1,4-androstadien-3,17-dione, on rats. The most striking outcome of that study: dienolone is strange stuff.
The research workers, Alvin Matsumoto and Brett Marck, administered rat implants which delivered steady levels of the steroid hormones, and also gave rats in a control group implants without active substances (placebo). Eight weeks after the operation, the researchers looked at the effects on the animals. Boldione raised the concentration of testosterone in the rats. Could the antibodies that the research workers used for the boldione analogue have been confused with testosterone? (See Diagram below) Dienolone raised the levels of estradiol in the animals. That is logical. Dienolone seems to convert fairly easily to estrogen.
The concentrations of LH and FSH, the two driving hormones which induce the testes to produce testosterone, were diminished by the administration of both hormones. Remarkably, after the administration of dienolone the weight of the testes increased. This is seen in the figure below.
Then the researchers tested the anabolic / androgenic properties of the two steroids shown via the sizing of the prostate and the levator ani muscle of the rats, as shown in the diagram below.
From the results you would think that dienolone was a more powerful anabolic / androgen than boldione. However this was not the case. The above figures are in relation to the relative weights: the weight of the levator ani muscle and the total body weight of the rats. The rats that received dienolone had gained less weight than the other animals, but mainly because they were less willing to eat. Below you see the weight increases of the test animals. The rats who received dienolone had a larger increase in the weight of the prostate and levator ani muscle, which was not surprising. The fact that the rats who were administered dienolone had an enlargement of the testes, could not be explained. The research workers think that dienolone decreased the appetite because it converted into estradiol. In 1978, researchers discovered that androgens which convert to estradiol especially decrease ones appetite. Weight changes are shown in the diagram below.
