The purpose really is not round the clock hormone enhancement it's the anabolic shift that the body undergoes when in the prescence of high levels of hormones. Take it all at once or spread out your choice I think that in the long run it will make no difference. Even if you look at our natural test levels the levels dip and peak at different points in the day and night so why shouldnt the exogenous ones we are taking? Plus if the HALF life of anavar is 9 hours, which is possible though unlikely then even after 18 hours 1/4 of the dose is still active. Just some thoughts.