I do think there are brands that are simply working with a larger markup than others. If you have an idea of what costs what from companies that are known quality operations you can then look and see who is simply making a larger mark-up. Take creatine mono pricing is all over the place on that one but a quick search for creapure shows three companies ranging from 17.99-26.99 for 500g. So when I see any brand selling 60 servings of 5g each for $20.00 I don't think it is a higher quality I think it is, put nicely expensive(talking mono only here.)
Same thing go for isolate: if it costs more per lb than say Now, Nutrabio and true nutrition I consider it overpriced, personally.
Often times boutique brands that market to specific crowds, not bodybuilders, and often women are very overpriced. Case in point look at Beam Dream: combo of reishi, theanine, mag citrate, hemp oil and melatonin 30 servings for $95.00, no chance in hell lol. They market heavy to crossfit and have many of the top athletes endorsing them, and you pay for that. I don't think there product is any better than say Irwin Naturals who makes a CBD sleep formula that is about a third of that price.
You get what you pay for to a point.