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  1. Kelt

    NMT Headaches... Anyone else?

    I do not dare to educate anyone within chemistry. I myself am educated within electrical engineering, currently trying to finish my Ph.D. studies within applied signal processing. However I do not mind to debate matters which I am interested in since also I am eager to learn. And what better way...
  2. Kelt

    DMAA Alternative

    No problem, I was just curious about your point of view, due to your years of experience.
  3. Kelt

    DMAA Alternative

    From what I could understand the definition of an tryptamine family of compounds is a molecular structure where the amine is attached to an indole with an ethyl chain, that is 3-(2-aminoethyl)indole. If we take the LSD as an example it also have the aminoethyl chain locked in a ring structure...
  4. Kelt

    DMAA Alternative

    As I understand it, only the 5-methoxytryptamine is an actual tryptamine. I never heard about the other two compounds. Alexander Shulgin wrote a really interesting book about tryptamines, called Tihkal. Many of the compounds are not legal, but the most interesting is his discussions about the...
  5. Kelt

    DMAA Alternative

    Thank you for the time to explaining this. Regarding yohimbine from the other thread, we could say that it is a sort of a tryptamine based stimulant? It has an indole, but do not know if the locked amine in that side position classifies to be considered as tryptamine. From what I could read it...
  6. Kelt

    NMT Headaches... Anyone else?

    What you are describing here does fit the descriptions for symptoms of serotonin syndrome. At least for the autonomic effect part.
  7. Kelt

    NMT Headaches... Anyone else?

    Could these adverse effects perhaps be because Yohimbine is a tryptamine related compound that fiddles with way too many types of 5-HT serotonergic receptors?
  8. Kelt

    DMAA Alternative

    Yes, I found a documentary on youtube about this. Apparently someone made an analog to LSD with a bromo (Br) atom attached to it. This “tweak” prevent this analog to be hallucinogenic, due to the size of the bromo atom, however the effect of eliminating cluster headaches is still there. I think...
  9. Kelt

    DMAA Alternative

    Yes, that is true. Dr. David E. Nichols has a nice lecture on youtube, where he does explain this phenomenon.
  10. Kelt

    DMAA Alternative

    Hmmm, would that be a possibility even if the compound is still fully legal? I do understand that the dosing is very critical, but I am surprised about the legality issues. Just out of the curiosity, when you investigated tryptamines, was it only theoretically or did you also made some...
  11. Kelt

    DMAA Alternative

    Well, from what I could dig up, the Psilocybin do not only give you the good feeling. Many do report increased focus, energy levels and productivity at work.
  12. Kelt

    DMAA Alternative

    I presume why LSD is so stimulatory is due to the fact that it also stimulates dopamine receptors and a whole bunch of other receptors.
  13. Kelt

    DMAA Alternative

    Yes, since tryptamines are serotonergic agonists, they will make you trip at higher doses. But I was just wondering, if there would still be a legal compound that stimulates same serotonergic receptors as Psilocybin, would it not be of an interest at very small doses? I do understand that you...
  14. Kelt

    DMAA Alternative

    Well Dr. Fadiman was experimenting with LSD in 25mcg doses, or rather he asked volunteers to report their experience with such a small doses. This due to the fact that LSD was already scheduled. The same effect has been reported from users of psilocybe mushrooms, where the definition of micro...
  15. Kelt

    DMAA Alternative

    On a side note, as I see that you also experimented with NMT which is a tryptamine with poor oral bioavailability (according Shulgin, #50 in Tihkal). Now I do not exactly know the laws around tryptamines, but did you researched the possibility of finding a legal and natural tryptamine with good...
  16. Kelt

    DMAA Alternative

    I presume that what is special with DMAA is that the molecule is methylated on the alpha position protecting the amine from MAO? Also due to only a partial phenyl ring structure it cannot be considered as amphetamine analog? The pity with most PEA analogs (including halostachine) is the lack...
  17. Kelt

    DMAA Alternative

    Interesting, is it not that essential amino acids in the free form are considered as pharmaceutics in Norway?
  18. Kelt

    DMAA Alternative

    +1 These are really good questions.
  19. Kelt

    DMAA Alternative

    Oh, I see, this is how it goes when I read something outside of my area after midnight.:ouch: However, I cannot stop wondering that the prediction in ACD/I-Lab can be so wrong. They use predictions of LogPS (rate of brain penetration), LogPB/LogBB (extent of brain penetration) and Log(PS*fu...
  20. Kelt

    DMAA Alternative

    So I reread the pointed out article. Now, biochemistry is only my hobby so I am sorry if my following speculation is totally wrong. The test in that article has been conducted on the heart muscle and I presume you ware referring to the results in influence of calcium ion channels by higenamine...
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