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  1. YUP, SHBG 82.4, HELP!!!!!!!

    My SHBG was in the 70s but my E2 was high. Your E2 seems on the low side for explaining this. I had some flakey labs so you may want to repeat for confirmation. You should give some effort to seeing if there is another reason for the high SHBG as the Matrix suggests before jumping on Aromasin...

  2. Free estrogen testing

    I'd be interested in a reference for this if you have one. This condition would prevent DHT from going back up but it shouldn't cause it to go down. Even if this applied to me, however, my previous DHT test result is bizarre. It is unheard of to be at 19 on a full dose of Avodart. I just...

  3. Anastrozole (tradename Arimidex) and its impact on CYP3A4 and liver function

    Great thread - very apropos for me now. Yeah, but watch out for Quest's ultra sensitive test. I heard that they sometimes screw it up and after my last results I really believe it. Fortunately at the same time I also got their free estradiol test which also reports a total E2. Check out...

  4. Free estrogen testing

    Free Estrogen Testing: New Labs!!! I just got back new lab results taken after lowering serum levels of Avodart by 22%. Some results were anomalous. Testosterone dropped from 929 (250-1100 ng/dL) down to 741. A drop was expected but this was a little more than expected although still...

  5. Anti-aging success stories

    This is not boring but it is also not a success story of the kind I am looking for. Some of us are not so lucky and either end up sick or simply suffering the effects of aging despite having a healthy lifestyle. This is an anti-aging forum so I was hoping someone managed to succeed in actually...

  6. Anti-aging success stories

    I'm interested in hearing anti-aging success stories. Something along the lines of I'm 50 years old and and tried xxxx and now I feel like I'm 20 years younger. It seems that people are more inclined to post when they have problems but I did see at least a few positive postings in looking...

  7. Lurker here... With test results and need opinion.

    The Matrix may be on to something because your TSH is on the highish side by more stringent standards. The E2 is more important than the DHT but the more you test the less likely something will be missed. Your story about gaining after a period of semi-starvation resonates with me. The only...

  8. Lurker here... With test results and need opinion.

    You really need to research this carefully before you start doing the more serious stuff like TRT. I understand you want to solve this quickly but you can make hard to reverse mistakes. Your T is clearly on the low side and your SHBG is also low. Your free T is in range probably because of...

  9. Free estrogen testing

    1) My SHBG is 72 (9-45 nmol/L). This makes it ambiguous as to whether my E2 at 28 is too high or too low. The high SHBG suggests too high but the E2 doesn't support that. 2) I think men vary on whether Avodart makes sense or not. I'm taking it to prevent BPH. The only downside I noticed...

  10. Free estrogen testing

    I presume that you still think that SHBG is a sufficient surrogate for these other estrogens. Anyway, I have done all I could for my gut and need to move on. I've read about your experience with Arimidex and can understand why you don't like AIs. Other people have similar troubles with this...

  11. Free estrogen testing

    Thanks for the response Matrix. I don't doubt there can be non-obvious gut issues. Nor do I believe that my gut is perfect now. The main point is that we were all over my gut for several years and did that to death. Any bug or parasite you can think of we already looked for. By the way, do...

  12. Free estrogen testing

    Just to be clear, when I said malabsorption is in my history I meant as manifested by food intolerances. This was a big issue for me about 10 years ago and it was a major focus of my doctors at the time. Food intolerances have long ago become practically a non-issue for me and my diet is much...

  13. Free estrogen testing

    Thanks for the tip on zinc and copper. I have been taking zinc regularly lately but copper only sporadically. I have no sense of what these do for me. Estrogen at 28 may or may not be fine. DragonRider as I recall says he needs to be below 15. This is not typical but people do vary and I...

  14. Free estrogen testing

    I have been more thoroughly evaluated than most. I feel that I've got the first 50% covered as best I can. There are no liver issues or insulin issues. Mal-absorption is in my history but controlled about as well as I can realistically expect for many years now. Mal-absorption was much worse...

  15. Free estrogen testing

    Quest sensitive test result was 28 pg/mL which is just below the reference range of <29 pg/mL. I'm not sure about REM sleep. All I can say is that sometimes I sleep better than others. As for wood, that is sometimes there and sometimes not. I feel like I am fluctuating on the borderline.

  16. from well endowed to shrunken penis / what would you do.???

    Your tests show adrenal issues which I would guess have to do with your being stressed out by this problem. The answers are not clear yet but in the mean time you should try to relax and convince yourself that you will figure this out. I'm not just saying this - I think you will figure it out...

  17. Free estrogen testing

    I did that already and my e2 was in the normal range (albeit at the top of it) and my SHBG is very high. So now I am not sure if my e2 is too high or too low. My symptoms tell me it is one or the other but the test results are ambiguous. It is possible that even if I get the free e2 test that...

  18. Free estrogen testing

    Free Estrogen Testing This thread is effectively a continuation of the thread called "Muscle injuries despite high T and IGF-1" Why doesn't anyone seem to talk about getting free estrogen testing like Quest's 36169X - ESTRADIOL, FREE, LC/MS/MS? After all isn't it the free estrogen that...

  19. Muscle injuries despite high T and IGF-1

    I'm wondering if I have been thinking about this wrong. I believe that the blood test that I got is for total E2. If so then with a very high SHBG and normal estrogen levels perhaps my free estrogen is in fact on the low side. Should I be getting a test for free estrogen? Is Quest's 36169X -...

  20. New on TRT.... High Estrogen - Arimidex Dosage advice

    That 1mg is 12 days worth at .25mg/3days. I'd wait this long before the next .25mg dose.
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