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  1. JakeAntaeus

    Tomatidine (potent natural anabolic?)

    Yeah, Endothil-CR. But wasn't it something like 5-10mg of a non-standardized green tomato extract per Endothil-CR tablet? If so, then of course it wouldn't do anything. There'd be micrograms-to-nanograms of tomatidine per tablet. But it's interesting to note that the mere existence of...
  2. JakeAntaeus

    Tomatidine (potent natural anabolic?)

    With respect to extraction vs. synthesis, the former is just more economical. You understand, I hope, that I can't go into more detail than that. Patents on natural phytochemicals are always extremely weak. At best. (Were they otherwise, patent US9387168 would not be possible!) Note that...
  3. JakeAntaeus

    Tomatidine (potent natural anabolic?)

    First of all, thanks for the support. It's truly appreciated, and I would really like to hear how the product works out for you, so I'd be much obliged if you would take the time to share your honest feedback. With that out of the way, a couple of comments on dosing: -That it was effective at...
  4. JakeAntaeus

    FOLLIDRONE 2.0 USER RESULTS

    Well, the way I see it, whether or not Pfizer is working on a monoclonal antibody for myostatin is rather irrelevant. In any case, there's no need for a battle of cherry-picked studies. I think that this is amenable to logical formalization: 1. Follistatin stimulates hypertrophy via...
  5. JakeAntaeus

    Tomatidine (potent natural anabolic?)

    Respectfully, "98% Tomatidine" doesn't exist. Look at the material from Sigma, Enzo, EMD Millipore, and Cayman. It's all, without exception, "85%+", "90%+". Not even those companies -- which charge hundreds of dollars for 100mg, and which always sell the highest purities they can get their...
  6. JakeAntaeus

    Tomatidine (potent natural anabolic?)

    Before releasing the product, we carefully tested tomatidine in cyclodextrin complexes, phospholipid complexes, and shilajit complexes. In terms of dissolution, the cyclodextrin (HPBCD) and shilajit complexes were roughly equal -- but the shilajit complex dissolved much more rapidly in water...
  7. JakeAntaeus

    The New Product Release Thread

    That product may have contained nanograms of tomatidine per serving, and that's likely a generous assessment. I think it was something like 5-10mg of a non-standardized green tomato extract per Endothil-CR tablet. Tomatidine extraction and purification is incredibly difficult, and there's no...
  8. JakeAntaeus

    3,5 T2

    In fairness, you asked what results you could expect, and I said that there's really no way to say, but that the paper may provide something of a benchmark. I should mention that there are all sorts of issues with that paper, though... Not solely limited to the small sample size, which, in...
  9. JakeAntaeus

    Ultimate Bulking Stack: would this work?

    Totally off-topic: Please free up some space in your PM inbox. Thank you!
  10. JakeAntaeus

    Best cutting supplement

    Two humans... and a heap of other studies, most of which are in no way inferior to the ones you posted yourself. 3,5-T2 has got more data backing it up, and more compelling data, than many other supplement ingredients. Fair enough, mate. I feel the same way. Readers of this thread can draw...
  11. JakeAntaeus

    Best cutting supplement

    Extrapolating data? They got noteworthy results in humans with 3,5-T2, at a moderate dose. There's nothing to "extrapolate." (In itself, it's not quite as strong or as conclusive as I'd have liked to see, but such is life.) One extrapolates from animal studies and in vitro data. One can...
  12. JakeAntaeus

    Best cutting supplement

    It's called a case report study. The results they obtained -- in humans, no less -- still attained statistical significance. This generally indicates that said results are promising, hence worthy of publication, rather than the opposite. Besides, what you're doing isn't cherry-picking? There...
  13. JakeAntaeus

    Best cutting supplement

    Are you referring to 3,5-T2? If so, your own post doesn't support this conclusion. You link to two studies; one goes so far as to say "the ability of T2 to increase metabolism is not in doubt", whereas the other concludes, in its bottom line, that "3,5-T2 (but not 3,3'-T2) seems to mimic the...
  14. JakeAntaeus

    Is prime nutrition legit?

    There are a couple of easy tests for taurine. Perhaps the easiest: Dissolve 2g of taurine in 40ml of freshly boiled and cooled water. Grab a pH stick. The pH of this solution should be right around 4.8. The solution should also be completely clear and colorless. In any case, I'm sure it's...
  15. JakeAntaeus

    What is the best legal estrogen inhibitor on the market !?

    No. The major 5a-reduced metabolites of formestane have been tested for aromatase inhibitory activity, and appear to be completely inactive. See: "Pharmacokinetics and metabolism of formestane in breast cancer patients", available at docdro.id/jtu0Ewl What's more, formestane's potency has...
  16. JakeAntaeus

    What is the best legal estrogen inhibitor on the market !?

    To the contrary. Seems as though it's fairly significant. See, for instance: docdro.id/yrwT4El & docdro.id/67l4uLz To sum up in a couple of sentences: Via the oral route, in humans, formestane and 4-OHT were indistinguishable -- they had the same exact metabolites -- which suggests ready...
  17. JakeAntaeus

    What is the best legal estrogen inhibitor on the market !?

    Incorrect. It's because a rather significant amount of formestane would convert to 4-hydroxy-testosterone, which is, of course, an androgen. Invalid Link Removed
  18. JakeAntaeus

    Antaeus Labs: 3,5 T2

    8 weeks should also be fine. There are no hard limits that are set in stone -- unless there's hard data that I'm unaware of, anything that anybody says would be conjecture -- but I believe that people who don't do regular bloodwork should go no further than an 8-weeks-on/4-weeks-off dosing...
  19. JakeAntaeus

    Antaeus Labs: 3,5 T2

    Clinical data suggests that it's not significantly suppressive. (See PMID 22217997: Antonelli et al. 3,5-diiodo-L-thyronine increases resting metabolic rate and reduces body weight without undesirable side effects. J Biol Regul Homeost Agents. 2011;25(4):655-60) ...But, with that said, I...
  20. JakeAntaeus

    Antaeus Labs Hydra Head 6 -- Ultimate Anticatabolic

    It should ship within 24 hours. It's in stock right now -- if retailers don't have it, it's because their orders are still in transit -- so our own small website has first availability.
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