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  1. Saint Johns Wort

    I never claimed that all antidepressants are Anxiolytic. SSRIs just happen to be one type that people are familiar with. As I said in an earlier post. Herbals work, but they are unregulated and much more difficult to properly dose. So why would you want to consume an extra gram of ground up...

  2. 9-MBC

    I need to look at that in detail. What is their measure of neurotoxic effects? Did they look at all cell lines? Was it just dopamine cells? Are you taking this stuff?

  3. 9-MBC

    I have not denied the effects on dopaminergic cells. Dopamine is a neuromodulator, meaning it helps regulate brain activity but does not directly drive it. You can lose up to almost 90% without experiencing deficits. It's not important enough to ingest a substance that is toxic to the neurons...

  4. 9-MBC

    This is the study that sold me at first. However the fact that it is neuroprotective of dopamine does NOT mean that it can not and will not kill other cell lines. How about this study? Phoneutria spider toxins block ischemia-induced glutamate release and neuronal death of cell layers of the...

  5. 9-MBC

    What does metabolism have to do with the effect of a drug? Most of the studies that found a positive effect were cell culture. Either way, I'm not trying to convince you that it is 100% toxic and not to take it. What I'm saying is that the evidence suggests that it is in fact a neurotoxin...

  6. 9-MBC

    I will post the title of the studies that state it is a neurotoxin. Synthesis, acute toxicities, and antitumor effects of novel 9-substituted β-carboline derivatives 9-Methyl-β-carboline up-regulates the appearance of differentiated dopaminergic neurones in primary mesencephalic culture...

  7. 9-MBC

    I literally cannot post links. It's not allowed. My account doesn't have enough posts. I had 7 links that I tried to post. Just read the articles that you're "reading". All but maybe one State that it's either neurotoxin or a cytotoxic.

  8. 9-MBC

    No, if it has amazing effects it MIGHT be ethical to research the effects of a compound that has neurotoxic effects in healthy himans. If it has a net effect of killing brain cells it really doesn't matter if it protects and help recover dopaminergic cells. Stop offering to help me understand...

  9. 9-MBC

    I read the studies. I thought it was an interesting compound at first glance but after reading all ive seen is that it prevents damage from mptp and mpp. These are dopaminergic neurotoxins. This is evidence that it can prevent and possibly reverse mitochondrial damage in dopaminergic cell lines...

  10. 9-MBC

    I'm sorry man I cant post links. Go to Google scholar, do a search an read the studies. All of these very clearly state that it is either an a) cytotoxin or b) neurotoxin I dont see a single convincing study. There was one study that I found interesting, I asked you about it and you didn't...

  11. 9-MBC

    Youre confusing me with someone else. I know exactly what it is and how it's different. Im an electrophysiologist, I study the midbrain dopamine system, with a current focus on Parkinson disease.

  12. 9-MBC

    So then how does it work. It's a known neurotoxin, it's very clearly dangerous despite the positive effect on dopaminergic cell lines. What was the % increase from baseline in the study on hippocampal based learning?

  13. Biohacking devices experiences?

    I drew up my own plans for it using a 9V battery, milli-ampmeter, in-series resistors with a variable resistor, and a simple on/off switch. I set the resistance so that a fully charged battery couldn't produce more than 2.5 milliamps current (for safety) , and adjusted the variable resistor for...

  14. Biohacking devices experiences?

    I've used it for enhancing Cognitive function, mostly for improving focus, energy & mood. The results are subtle at first but become more pronounced over the first week and they peak at about 2 weeks. It's less effective than prescription stimulants, yet more effective than caffeine. I've used...

  15. Biohacking devices experiences?

    I have have a bunch of experience with tdcs devices. They work very well.

  16. 9-MBC

    NeuroTropic Thanks. I have been reading a few of the studies. I didn't come across anything that said the effects were dose dependant however. I did see that these compounds are generally regarded as cytotoxic, and that they protect against mitochondrial damage. This may make them...

  17. Saint Johns Wort

    Antidepressants are Anxiolytic, as well as antihistamines being Anxiolytic too. Doctors will not easily prescribe Benzos for general anxoety for a multitude of reasons. The main reason being the side effect profile vs the effects. The effects are overkill for most cases of general anxiety and...

  18. 9-MBC

    Wow, Redman is shot. He has some basic knowledge, but not enough to form valid opinions. Is there any evidence for this compound actually causing a conformational change at the GABA a receptor? Does anyone know why there might be differences in the literature between 9-methyl-β-carboline and...

  19. 9-MBC

    This stuff looks cool. I'm going to have to read up in it a bit more before I believe the hype though.

  20. Nootropic to enhance psychological performance - 9-MBC @PredatorNutrition - Save 7%

    This stuff looks awesome
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