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  1. bigdavid

    T3, why some say yes it's awesome and some say don't touch it ?

    If no thyroid condition is present you will not have problems longterm. Emphasis on longterm. As stated above it can take weeks to get back to your normal levels. The thyroid is very resilient, though. You can suppress it for decades and it will still start back up again (assuming the only...
  2. bigdavid

    Best Nootropic For Mood And Happiness

    From Invalid Link Removed “Our results show that, though benfotiamine strongly increases thiamine levels in blood and liver, it has no significant effect in the brain. This would explain why beneficial effects of benfotiamine have only been observed in peripheral tissues, while sulbutiamine, a...
  3. bigdavid

    Best Nootropic For Mood And Happiness

    Looks like s good formulation. Though I don’t know why they put in benfotiamine. It’s a thiamine derivative that doesn’t readily cross the bbb like sulbutiamine does. Maybe it can give your body some benefit that can be indirectly felt cognitively. Idk.
  4. bigdavid

    Best Nootropic For Mood And Happiness

    And in terms of cognition there are several antidepressants that only alleviate mood and not the cognitive aspect. But ones that can actually increase cognition, slightly above baseline if you are currently even a little depressed, are Zoloft, mirtazapine (45-60mg dose not lower), trintellix...
  5. bigdavid

    Best Nootropic For Mood And Happiness

    So after flipping through this thread again I think it’s important to mention that re the topic (nootropic for MOOD/HAPPINESS) any compound that increases acetylcholine levels or augments them can lead to worsening of depressive symptoms. I can’t use acetylcholinesterase inhibitors for more than...
  6. bigdavid

    Best Nootropic For Mood And Happiness

    You should deff notice effects from that dose after only a few days if not the first day. It won’t always be super apparent. But you’ll make less “careless” mistakes if you were doing any type of math or computing. And you’ll feel sharper in general. It’s deff one of the most reliable nootropic...
  7. bigdavid

    Best Nootropic For Mood And Happiness

    It’s definitely a great compound but with anything that can affect chemicals in the brain (which is what the acetyl group does...and not just acetylcholine but also serotonin is increased) you want to start small if anything then go higher. High doses of ALCAR believe it or not have been...
  8. bigdavid

    T3, why some say yes it's awesome and some say don't touch it ?

    In that case just get the TSH and you can compare that to your future value and how you feel. Just assume your levels of T3 and T4 are normal and if you have problems after you use T3 then you can spend money on additional tests if you need to.
  9. bigdavid

    T3, why some say yes it's awesome and some say don't touch it ?

    Honestly people will disagree but as a “screening” tool TSH by itself is fine. If you don’t have symptoms and your TSH is normal then you are fine. If your TSH comes back abnormal or borderline then get more tests. But it’s not worth the $ since you are paying for it yourself
  10. bigdavid

    Best Nootropic For Mood And Happiness

    Yeah I’ve never heard of front loading ALCAR and don’t think it would even work in that fashion. Just do 2-3 g acutely or .5-1 gram (sub)chronically.
  11. bigdavid

    T3, why some say yes it's awesome and some say don't touch it ?

    TSH and free T4 should be fine. Some endos also do total T4 and T3. But TSH and Free T4 are adequate for diagnosing any thyroid issue usually. But to be comprehensive, assuming it doesn’t cost you extra if insurance covers it, do: TSH T4 Free T4 T3 (Free T3 If you want to be extra anal about...
  12. bigdavid

    Add anavar to first test e cycle?

    ^Agreed.
  13. bigdavid

    Antibiotics while on cycle?!

    They shouldn’t interfere with the cycle and they aren’t liver toxic to a degree that would hurt you. At least not from only two weeks. I think you should be good but also play it by ear if you get more side effects than you would expect from just the cycle alone.
  14. bigdavid

    Antibiotics while on cycle?!

    What antibiotic? Dose? How long will you be taking them?
  15. bigdavid

    Does anyone NOT take a preworkout before a workout?

    It has a similar neurological effect as the antidepressant mirtazapine (mirtazapine has other effects also). Y antagonizes alpha-2 receptors which causes an increased release of Norepinephrine and to a smaller extent serotonin in the brain regions responsible for mood and attention regulation...
  16. bigdavid

    Hi-Tech Pharma: Pro IGF-1 Blood Tests @ 20mcg/day

    kinky
  17. bigdavid

    bigdavid's AZOTH 2.0 log (sponsored)

    Just got back from a fantastic back/bis workout. Took my 3 caps preworkout with my usual preworkout stims (so I know how those affect me). And I can say I felt like contractions were easier. Like my arms would flex the weight up before my mind even registered that it had to be done. Not a rushed...
  18. bigdavid

    bigdavid's AZOTH 2.0 log (sponsored)

    Sorry for being MIA for the past few weeks. I finished my first bottle of AZOTH and had more consistent increase in focus and memory like I’ve noted in previous posts. I took about 2 weeks off from the first bottle and today I am going to start bottle #2. I’m interested to see if I get the...
  19. bigdavid

    bigdavid's AZOTH 2.0 log (sponsored)

    You deff can! The products have no overlapping ingredients, and the creatine, agmatine, And stimulant profile would deff add if not synergize with the ingredients in AZOTH. Preworkout cholinergic compounds can increase power output, I know a lot of guys that use 300-600 mg alpha-GPC preworkout...
  20. bigdavid

    Hi-Tech Pharma: Pro IGF-1 Blood Tests @ 20mcg/day

    Igf is a protein found in natural sources it can’t be targeted since it is a dietary supplement that has been in the food supply for ages.
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