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  1. bigdavid

    TOO HUNGRY!!!

    Serotinergic agents always kill my appetite. Not saying to go on an ssri. But 5htp seems to work well for this purpose. Also low doses of citicoline can reduce appetite.
  2. bigdavid

    Cialis as estrogen control?

    Have read some journal articles mentioning a somewhat vague-mechanism for cialis improving test:e2 ratio, but nothing specific talking about it being an AI or serm or having any of those properties. I just wanted to give my experience of needing little if any e2 control while currently on test...
  3. bigdavid

    Looking worse after steroid cycle

    I agree with you here re: how long it takes to recover from AAS. A 4 week or even 8 week pct doesn’t really get you back to “normal”. It takes months for that to happen. Majority of guys I know just take 8 weeks off and go back on. I personally couldn’t deal with the ups and downs of pct so for...
  4. bigdavid

    Best Nootropic For Mood And Happiness

    Everyone likes to blame their problems on *something*. Some people latch on to the one theoretical example that makes sense to them in terms of causing all their problems, then they hold on and never let go...that is until they realize they were wrong and latch on to another false or exaggerated...
  5. bigdavid

    Best Nootropic For Mood And Happiness

    I can say that chronic usage causes slowing. And acute usage of over 3-400 causes slowing also. Honestly haven’t really experimented with less than 300 at one dose. Chronically though the slowing tends to get better after a few weeks of consistent dosing but it still isn’t really a go to...
  6. bigdavid

    Best Nootropic For Mood And Happiness

    I know the majority of individuals like this supplement, I myself find it beneficial in some instances. However, only in small doses (vs what others seem to be taking). If I take a full 600 mg dose of the standardized version, I feel almost zombified and mentally slow. Have you gotten this...
  7. bigdavid

    Best Nootropic For Mood And Happiness

    Something to keep in mind in regards to taking 5HTP for mood purposes, is that if you do want this effect you likely need to take the supplement (sub)chronically for any real changes to be noticed. Since the MOA of SSRIs is to nonspecifically increase serotonin in synapses, with no real receptor...
  8. bigdavid

    The Arachidonic Acid Help Guide

    You certainly are not alone in your experience. Having preexisting injuries and/or an established inflammatory based disease/condition can definitely lead to exacerbations with ARA supplementation. It’s important to remember that the studies showing no increase in inflammatory markers or...
  9. bigdavid

    The Arachidonic Acid Help Guide

    I am not sure if someone mentioned GLA supplementation in regards to ArA supplementation, so I thought I'd add this info to the thread. I have a bottle of borage oil in my cabinet and was considering trying it again for eczema (not proven to work here but I already have the oil so what the heck...
  10. bigdavid

    The Arachidonic Acid Help Guide

    If anything quite the opposite. The signaling that occurs from arachidonic acid during and after exercise increases insulin receptor sensitivity, as well as igf-1 receptor sensitivity, among others.
  11. bigdavid

    bigdavid's AZOTH 2.0 log (sponsored)

    Ahh. Man I would have sworn I had updated this log a few weeks ago. Just noticing that it didn’t go through. I’ll post up my remaining week or two of use of this product over the next day or two. I have most of my notes saved in a file on my computer. I’ll also give a final review both here and...
  12. bigdavid

    Making my own PWO From bulk

    In response to the creatine-agamatine interaction, that one is purely theoretical and at the nmda receptor. Creatine being an agonist, agmatine potentially being antagonistic. That receptor/pathway really has nothing to do with workouts, pump wise or even focus wise. And the influence of...
  13. bigdavid

    T3/T4

    Well unless you plan to stay on T4 indefinitely, or for a very long period of time, it’s much harder to recover normal thyroid function if you take T4 on top of T3. You will likely have little suppression if you only use a low dose of T3, but when you add T4 you are almost guaranteed suppression...
  14. bigdavid

    T3/T4

    Yeah man you don’t need T4 at all. My family has a long history of hypothyroidism and I was no exception when I hit my 20s. That’s why I take the T4. T3 I take for antidepressant effects so that’s why the dose may seem high in my specific case. Like everyone has been saying for physique purposes...
  15. bigdavid

    T3/T4

    I’ve used 150 mcg T3 and 200 Mcg T4 for months in between cycles not on any exogenous hormones and honestly I don’t think I lost any LBM or at least not more than I would have anyway. Recently I’ve dropped the dose to 50-100 mcg for T3 and am currently on a cycle. It gives me a slight bump in...
  16. bigdavid

    Making my own PWO From bulk

    When I first heard/read about using PDE5 inhibitors preworkout I too was very skeptical. But like you said after trying it once you realize it’s deff effective and not your buddy messing with you. Did a chest/shoulder workout the other day with cialis Pre, also had some citrulline and whatever...
  17. bigdavid

    Making my own PWO From bulk

    Yes if there is one thing to take away here it is that cellular assays do not carry over well to entire organisms...it’s only used to elucidate pathways and figure out details that might happen in certain situations but you can’t go from macrophages to human and expect carryover. So crohn isn’t...
  18. bigdavid

    Injection site

    You can actually use more than one site and I think they are both technically quads. Upper outer quadrant of the quad muscle is good since it’s not near any nerves. Also mid-thigh directly lateral is another spot. I think that one is vastus lateralis? Forget. Shoulders are fine too. But...
  19. bigdavid

    Best Nootropic For Mood And Happiness

    Yeah I deff understand. There is a trend today for physicians to not want to give benzos out, some don't give them at all, regardless of the reasoning. Thats why I said "reasonable physician", because any dr that generalizes those abusing a drug to those using it for medical purposes, and using...
  20. bigdavid

    Is this overkill?

    At this point id just stay on the clomid dose and get blood work and see where you are. It may be hard to gauge estrogen levels at this point because some fat gain could be from simply being off cycle and your body isn't as anabolic as it was before. Recovery is different for everyone obviously...
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