The mechanism by which TUDCA can either prevent or excarberate alcohol-related liver damage is significantly different from how it would inhibit or accelerate steroid absorption into circulation.
What makes you think that?
Conditioning from the BB community, where none of the Injectible IGF-1 on the market is actually IGF-1?
Why do you expect doses that are a mere fraction of what medical studies indicate causes actual effects to work?
Because you'd be clearing that first pass faster. The goal is to get as much of a hormone into circulation as possible.
Cholestasis slows down absorption of substances that reach circulation through the hepatic portal vein.
Is 19-nor-DHEA an actual natural mammalian metabolite of DHEA?
The compliance case for 1-DHEA/4-DHEA has always been pretty abundantly clear to me, 19-nor-DHEA not so much.
The point of most methylated steroids isn't to be more effective by grinding the liver to a halt and drawing out their absorption over time.
The point of most methylated steroids is to survive that first pass metabolism at all.
I would actually expect the opposite, for TUDCA to accelerate absorption of methylated compounds into circulation if the person taking TUDCA was experiencing cholestasis.
Now, that might also increase clearance, but with most drugs the AUC is similar, and not having cholestasis is a good thing.
Got it, so roughly 7x the typical bro dose, but still much less than the medical dose.
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These guys are all getting doses in the numerous milligrams per day.
Circulating IGF-1 is in the multiple milligrams.
I'm really struggling to see the usefulness of 20mcg of IGF-1...
I'm interested in how a 20mcg dose increased circulating IGF-1 by more than 20mcg in 96 minutes.
Aside from this supplement, I'm also interested in why bodybuilders even use a 20mcg injected dose.
Has anyone posted their own bloods taking IGF-1 only with the usual 20mcg injected dose?
Because...
Why do they use that? Because the guy isn't actually a doctor or scientist and doesn't actually understand anything.
Nobody uses NNU for MPS because measuring nitrogen intake to urine excretion to determine MPS is not accurate.
You're vastly overanalyzing the scammy writings of a charlatan...
They've actually banned multiple nomenclatures of the same compounds on several occasions, because they apparently don't actually have anybody at the DEA that understands science.
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