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  1. Powercage

    Unanswered Does no one have issues with companies copying formulas?

    People that are allergic to gluten are the pussies of the allergy world. Take it from us lactose people, eat it anyway.
  2. Powercage

    Unanswered NAC hinders muscle growth

    This is the exact reason we run studies. Placebo is powerful and we are all prone to it. Some of your claims have potential mechanisms, but take recovery for example. Just like glutamine, HMB, and BCAAs before it, we know it doesnt help with that. We have replicated, controlled studies on...
  3. Powercage

    Unanswered NAC hinders muscle growth

    Man made vs natural has no bearing on mechanisms in question. Both are ultimately chemicals that should be considered on a case by case basis. Both can have unwanted side effects. For a healthy, natural lifter, the benefits appear to be modest (non-existent?) at best. With causative risk...
  4. Powercage

    Unanswered NAC hinders muscle growth

    No one said to stop taking all anti-oxidants. What you are missing is that anti-oxidants are good in certain contexts, until they start hindering natural processes or act like pro-oxidants (or are flat out unnecessary). You are under the misconception that antioxidants are always beneficial...
  5. Powercage

    Unanswered NAC hinders muscle growth

    Because most formulators are your average gym guy
  6. Powercage

    Unanswered NAC hinders muscle growth

    I agree, it is best not used near exercise. Although its effects seem to be on the level of days, not hours.
  7. Powercage

    Unanswered NAC hinders muscle growth

    sigh, that's why I said "the first two". The third issue is why I said way back in post #18 "unless you are under liver assault", and again in post #28 when I mentioned taking it with PH's, and again in post #30 when I mentioned cycling, and a multitude of other times I have said NAC would be...
  8. Powercage

    Unanswered NAC hinders muscle growth

    Your first two claims aren't based on anything empirical. The livers of triathletes, marathon runners and Crossfit Games athletes don't fail at an increased rate. I think we are okay as far as exercise goes. I did say it would be good for people who take cycles.
  9. Powercage

    Unanswered NAC hinders muscle growth

    Raised liver enzymes from the breakdown of muscle protein due to exercise is not the same as true liver assault, neither is protein intake (outside of already having liver disease), neither is the metabolism of nearly all OTC dietary supplements. Your liver can very readily handle these...
  10. Powercage

    Unanswered Does no one have issues with companies copying formulas?

    Hydrox came before Oreo. Let that sink in.
  11. Powercage

    Unanswered NAC hinders muscle growth

    Muscle soreness following the first and last sessions was not different between groups. We conclude that neither HMB-Ca nor HMB-FA improved hypertrophy or reduced muscle damage in resistance-trained men undergoing resistance training ingesting optimal amounts of protein. - Invalid Link Removed...
  12. Powercage

    Unanswered NAC hinders muscle growth

    It’s crap. You are either experiencing placebo or you are really low in your daily protein intake. When you ignore the outlier studies by researchers that are known for ridiculous studies, it isn’t shown to be overly beneficial. It doesn’t perform better than free form Leucine, that’s why...
  13. Powercage

    Unanswered NAC hinders muscle growth

    NAC also potentially increases DOMS. I dont see a particularly compelling reason to take it regularly (outside of when you are under intense liver assault). It shouldn’t be a staple imo. Daily supplementation with 1 g of oral NAC for six days produced no adverse side effects, reduced muscle...
  14. Powercage

    Unanswered NAC hinders muscle growth

    Not enough good research on Betaine to believe it would actually counter this. Very poor quality studies on betaine overall, but it has potential. HMB is pointless. It’s no better than a Leucine control.
  15. Powercage

    Unanswered Ecdysterone-Anabolic effect of ecdysterone strong enough to put it on the doping list

    Do you have any research with the mech on hand? Mechanisms in murine models do not necessarily translate to humans. If you are referring to increased MPS via Akt phosphorylation in rats, we haven't seen that in humans yet. We can keep saying this, but that hasn't been shown to be the case...
  16. Powercage

    Unanswered Ecdysterone-Anabolic effect of ecdysterone strong enough to put it on the doping list

    Both really. Since they both readily end up excreted. But still, why is a 50% higher dose showing zero response in trained individuals? It would be nice to see an isoproteinic study done.
  17. Powercage

    Unanswered Ecdysterone-Anabolic effect of ecdysterone strong enough to put it on the doping list

    Im traveling and dont have the radiolabeled study on hand. The only time its been shown in human skeletal muscle is using myotubes. If I had to venture a guess on why it could work, I would think it might be due to potentially increasing protein utilization.
  18. Powercage

    Unanswered Ecdysterone-Anabolic effect of ecdysterone strong enough to put it on the doping list

    This is one of my big concerns. We have the recent study showing near AAS gains Then we have other studies with verified higher amounts of ecdy (50% more, I believe) in use showing no change: Invalid Link Removed If I recall, the aas-like study showed 40mg pure ecdy in use. So what is...
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