Can second this. I've enjoyed it every time I've ran it, solo oral first time while cutting, stacked transdermal while cutting. Always consistent bump in pumps, recovery, sleep and mood/ focus...
I think it's probably best run in a stack. I used transdermal and definitely never experienced any form of shut down. I had the opposite basically, morning wood every morning.
Estrogen protects against insulin resistance by stimulating the transport of insulin into muscle cells, improving insulin's effectiveness on the liver and adipose tissue.
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