Recent content by sdstealth

  1. IGF-1 and Exemestane: Any Consensus?

    I just got my MRI report. They only used a 1.5T magnet (vs the higher resolution 3T magnet), but there was no large/apparent tumor of any kind and the pituitary and sella appear normal. Here's what that section says: "The pituitary gland size is within normal limits. There is slightly...
  2. IGF-1 and Exemestane: Any Consensus?

    Just to circle back on this, I got the results of my oral glucose tolerance test today. Completely normal at all time intervals on the test, with a fully-suppressed GH level. So whatever the cause of my elevated IGF-1, it doesn't seem to be a pituitary tumor secreting growth hormone. My body...
  3. IGF-1 and Exemestane: Any Consensus?

    I've never done HGH or used mk677. I'm a long-term TRT patient. The issue may be a pituitary tumor that's unrelated to any substance use. We're evaluating to determine the cause of the elevated IGF-1 as there isn't a good explanation at this point. The most common cause of this is a pituitary...
  4. IGF-1 and Exemestane: Any Consensus?

    Yeah I'm in the middle of an oral glucose tolerance test right now to check for active acromegaly. My IGF-BP3 is also above the range (about 40% + ULN) so my body is sensing that something is up, but not clear what the deal is.
  5. IGF-1 and Exemestane: Any Consensus?

    Okay, here's a bit of research I found. Looks like in women with breast cancer, exemestane was associated with a 35% increase in IGF-1 levels after a 120-day window. Invalid Link Removed
  6. IGF-1 and Exemestane: Any Consensus?

    Interesting, thanks. It definitely resolves my high E2 symptoms but I have to figure out why my IGF levels are elevated, so I'm trying to rule this out.
  7. IGF-1 and Exemestane: Any Consensus?

    Great, thanks. That's good to know. I actually had bloodwork come back with IGF-1 over the range, and I've been concerned as I don't want to have acromegaly. I've been using exemestane to control my E2 on long-term TRT and am going to come off the Aromasin to see if that helps correct the IGF-1...
  8. IGF-1 and Exemestane: Any Consensus?

    Can anyone comment on whether there been consensus achieved on the connection between IGF-1 levels and use of exemestane/Aromasin? I've seen conflicting reports on the way that different AIs affect IGF-1, and I'm especially curious if anyone can share both anecdotal and research-based info on...
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