Hypothyroidism can affect the entire body in many ways. Thyroid hormones act on virtually every cell you can think of - that is how important it is. There is a well known association between hypothyroidism and cardiovascular risk factors. There might also simply be a metabolic issue involved in...
Start simple and work towards more sophisticated assessments from there if necessary - blood pressure cuff, pulse oximeter, rule out orthostatic hypotension etc.
Low thyroid function (Primary Hypothyroidism). Can lead to elevated prolactin but so can other factors. Minocycline can affect thyroid directly - doxycycline doing the same thing is not unheard of. Possible dysbiosis from antibiotic can affect thyroid hormone metabolism, exacerbating underlying...
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