Recent content by Jon_b

  1. Jon_b

    cAMP and ADHD - Best of both worlds?

    What dose are you on for Adderall? Are you a heavy caffeine user?
  2. Jon_b

    cAMP and ADHD - Best of both worlds?

    Touey where did you find that?
  3. Jon_b

    Coop's Corner #1: Forskolin + B-agonists

    Excessive cAMP does seem to impair working memory, and other functions of the PFC theoretically. But it's hard to tell what is excessive cAMP and if oral forskolin supplementation would cause this level of cAMP increase in the brain. PMID: 17448997 cAMP increases do have beneficial effects in...
  4. Jon_b

    cAMP and ADHD - Best of both worlds?

    Any thoughts on a peripheral-only cAMP increasing agent? Something that doesn't cross the BBB perhaps?
  5. Jon_b

    Coop's Corner #1: Forskolin + B-agonists

    I came across this website as well. It doesn't really prove anything negative about forskolin. Only study cited that is of real relevance (at least in my mind) is the human one in which it shows actual positive results on testosterone and body composition. Other studies are done on rodents in...
  6. Jon_b

    ATP supplementation

    Hmm only way to make it work would be some form of time release or just have a short lived effect I guess.
  7. Jon_b

    ATP supplementation

    Interesting. Isn't there a reason why most of the science has gone with creatine as a way to increase ATP stores? What would be the benefit/drawbacks to oral ATP compared to creatine supplementation? Seems like I have read something along the lines of it not being able to be stored well in the...
  8. Jon_b

    cAMP and ADHD - Best of both worlds?

    Here's one of the references. There's mention of this system being the target for development of new drugs, and the current alpha agonists that are sometimes given are not strong enough to inhibit the cAMP increase by something like supplemental forskolin. Alpha2A-adrenoceptors strengthen...
  9. Jon_b

    cAMP and ADHD - Best of both worlds?

    There is a fundamental opposition between ADHD treatment and bodybuilding/general health optimization. Brief summary here on the science - ADHD impairs function of the pre-frontal cortex in the brain. This controls executive function, organization, planning, etc... cAMP is a secondary...
  10. Jon_b

    The Anabolic Minds Supplement Roundtable

    Creatine's effect on DHT should be taken with a grain of salt. There have been conflicting studies on that characteristic
  11. Jon_b

    The Anabolic Minds Supplement Roundtable

    Thanks! - Easy to trust info info from PA
  12. Jon_b

    The Anabolic Minds Supplement Roundtable

    Awesome idea. I've had a creatine question for a while... Once mixed in water is it stable? Or do you have to drink it within a certain timeframe so it doesn't convert to creatinine?
  13. Jon_b

    Ephedrine and caffein desensitization

    Agreed - clean energy and focus is great
  14. Jon_b

    Ephedrine and caffein desensitization

    Quadzilla, Rhadam, I just started EC stack and I am VERY interested in long term use. Do you have any references for the lack of tolerance buildup? Want to learn more about how that works
  15. Jon_b

    Coop's Corner #4: Alpha-2 Antagonism? Yes Please.

    He wasn't saying he was sedentary necessarily, just that he wouldn't make any changes to his current training routine.
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