Recent content by furion

  1. furion

    The Arachidonic Acid Help Guide

    As a histamine receptor type 1 (H1) antagonist Diphenhydramine can reduce hyperemic responses to resistance exercise, which is imparted by an indirect antagonist action at the endothelium. It is to be noted that this despite being sustained after exercise, this action does not appear to effect...
  2. furion

    Best appetite suppressant/all day energy

    I'll preface this by stating that I'm not having a dig at you here (I value your contributions) and I've actually seen this recommended elsewhere...I don't agree with using cimetidine for this purpose. Cimetidine is like the St John's Wort of synthetic pharmaceuticals- care must be taken with...
  3. furion

    Enzymes

    For an enzyme supplement to have any sort of chance of therapeutic efficacy it would need to A) pass through the stomach intact-to the small intestine; the main catalytic site. The stomach acid (pH 2-4) would undoubtedly hydrolyze the specific peptide conformation so this is necessary B)...
  4. furion

    Citrulline + pycnogenol , erections and breathing

    It is interesting that the leukotriene antagonist didn't do anything for you- but to be honest I have only really seen reliable therapeutic benefit in children with these. If it is an inconveniencing problem (especially so with exercise) it would be worthwhile trying inhaled nedocromil. There...
  5. furion

    Still shut down after 2 years?

    As previously mentioned, this would best be sought (in Australia) with a knowledgeable endocrinologist with specific experience in andrology. Depending on your location I may be able to recommend via PM. If you are still seeing your current physician(s) regularly for this, as you have...
  6. furion

    Way to increase the bioavailability/absorption of Ursolic Acid?

    By the looks of that XRD- it appears you have used a wet complexing method. It's really good to see that a company is manufacturing this using a reliable complexing method and actually quantifying it as well. For anyone who values my opinion- this would be a very worthwhile product for this...
  7. furion

    The Arachidonic Acid Help Guide

    Sorry I read straight over your first question. I can’t see any reason why ARA would affect your blood phosphate levels. Saying that there is also no direct evidence testing exogenous ARA on phosphate levels or in any disease states that predispose hyper or hypophosphatemia. Endogenously...
  8. furion

    The Arachidonic Acid Help Guide

    I’ll do my best to answer this, but may I ask why you want to know this? Given the idiosyncrasies and volatile nature of serum creatinine, especially in those who regularly partake in resistant training and have a decent amount of skeletal muscle tissue, it would extremely difficult to test or...
  9. furion

    Wow: Terminalia arjuna beat nandrolone in bone healing rates (animal study)

    There is major overlooked limitations to this study 1) The interventions and analyses administered and conducted was only done so over 4 weeks- All research identifying the anti-osteopenic/osteogenic activity of nandrolone has been conducted at a minimal of one year (with administration...
  10. furion

    The Arachidonic Acid Help Guide

    Very unlikely. Realistically, as previously mentioned (twice now), you would have to have prior established pathology present. The induction of the inflammatory enzymes (that biotransform ARA) is not result of the ARA alone, rather and endogenous process. Do you have prior diagnosed cardiac...
  11. furion

    The Arachidonic Acid Help Guide

    I'm assuming that by 'the heart' you would mean cardiac (heart) muscle tissue. If this is the case, then once again- there would need to be (an almost ongoing or intermittent) injury present for any potential augmentation of inflammation. You could extrapolate hypothetical substantiation using...
  12. furion

    The Arachidonic Acid Help Guide

    Best available evidence suggests that induction of intracellular oxygenase enzymes (in muscle during and after resistance training), should promote exogenous ARA active transport and passively diffusion from the serum (bound to albumin) into the muscle cell- to then act as a substrate for the...
  13. furion

    Element nutriceuticals ara?

    The excipient ingredients suggest it is a powder- therefore the arachidonic acid would be either adsorbed onto a carrier or as an acid salt, so at most would contain 10% active ARA. So you're likely getting 35mg per capsule.
  14. furion

    topical yohimbine with carbs

    I would say this is correct, at least from theoretical perspective- as the only research for transdermal yohimbine didn't test any kinetic parameters. Irrespective, endogenous insulin (in non diabetics) has a very large and rapid volume of distribution. Yohimbine chemical properties (molecular...
  15. furion

    iforce Intimidate SRT and Fluoxetine?

    There is literally no reliable safety data on supplemental NMDA. Hence this advice/information of any potential interaction with fluoxetine is purely theoretical. On a macro level- under 'neurotrophic theory of depression'- a pharmacodynamic theoretical interaction may exist between NMDA and...
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