Recent content by capnpappy

  1. Matrix coming to a billboard near you :-)

    AMP has 90 servings per bottle, Matrix has one serving per bottle. At least an RTD is in a single serving can, even 2 or 3 wouldn't be harmful, but 90 servings per bottle such as AMP? well....I could see not mass marketing something like that in case of possible carelessness or whatever...

  2. What compunds have anti-cancer/tumor shrinking properties?

    Interferon beta is used and easily mixed in solution, here's a brief article that summarizes: Invalid Link Removed and Interleukin beta is also widely used. Interleukin beta and interferon are "off-patent" and very expensive. maybe someone else knows if these are available as research only.

  3. Oratropin 1 Info

    LMAO, yeah, maybe! I've never shot a gun in my life. My brother-in-law is an Army ranger and he almost passed out in laughter when I told him I'm a gun virgin. The question that i have regarding IGF-1 and the BBB is whether or not IGF-1 receptors in the brain would create an affinity to...

  4. Oratropin 1 Info

    btw, jrkarp, I am going to keep arguing with you because I don't think, "Peace" will be in my best interest, considering your avatar.

  5. Oratropin 1 Info

    Intranasal is a good comparison to oral administration, or absorption in the mouth because the mucosa are interconnected. it is a better comparison than injection, that's all I've been alluding to. That was my take on that posted reference that "I POSTED" originally. I am not necessarily...

  6. Oratropin 1 Info

    A shill? jrkarp, got no problems with you, just discussing IGF-1 and the BBB. I posted that the weight in da were similar just to show the close relation of insulin to IGF-1, hence, receptor mediated trancytosis. It's an interesting discussion, IGF-1 and the BBB. IGF-1, if crossing the BBB...

  7. Oratropin 1 Info

    I looked up IGF-1 and insulin in the Merck Index 13th ed. and they are as follows, pretty close in Da: IGF-1 = 7648Da Insulin = 6000Da

  8. Oratropin 1 Info

    If one were to show how IGF-1/oratropin crosses the BBB originating from the mouth, using intranasal would be a good comparison.

  9. Oratropin 1 Info

    The brain contains insulin receptors. Insulin and IGF-1 both bind to the same receptors, they compete. If IGF-1 is receptor mediated, it would cross the BBB much like Insulin does. Insulin and IGF-1 are very similar in amino acid sequence (hence, "Insulin-Like") not sure about weight in...

  10. Oratropin 1 Info

    Quote: EDIT: Yes, IGF can bypass the BBB. However, there is no connection between this method of bypassing the BBB and your technology. Intranasal, pulmonary and sublingual are buccal mucosa targeted drug delivery.

  11. Oratropin 1 Info

    Delivering a peptide drug intranasaly would require receptor mediated endo/transcytosis which nerves are receptor mediated. Also, the nose and mouth are all part of the buccal mucosa.

  12. Oratropin 1 Info

  13. FDA cleared inhalent form of insulin:

    The FDA letter pharmacist received stated the pulmonary Insulin must be only taken before meals and you still need to use the injected Insulin after meals. Here's a link: Invalid Link Removed
See more
Back
Top