The effects of mesterolone on sperm count
in idiopathic oligospermia.
Bhathena RK, Jassawalla MJ, Patel DN.
Forty subfertile men with idiopathic
oligospermia were randomly treated with
mesterolone or with placebo for more than 4
months. Seminal analysis was performed
thrice before treatment, and twice after 16
weeks of treatment. There was a significant
increase of semen volume (P less than .05),
mean sperm concentration (P less than .01),
and mean total sperm count per ejaculate (P
less than .01) with mesterolone therapy.
Sperm motility and morphological
characteristics were not modified by
mesterolone therapy. Mesterolone was found
to be effective in improving the sperm
concentration in mild and moderate rather
than in severe idiopathic oligospermia.
Publication Types:
Clinical Trial
Randomized Controlled Trial
PMID: 2887529 [PubMed - indexed for
MEDLINE]